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Original Article

Effect of the Histamine-1 Antagonist Astemizole Alone or with Omeprazole on Rat Gastric Mucosa

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Pages 23-35 | Received 15 Mar 1990, Accepted 21 Jun 1990, Published online: 08 Jul 2009

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Read on this site (13)

Helge L. Waldum. (2020) Clinical consequences of controversies in gastric physiology. Scandinavian Journal of Gastroenterology 55:6, pages 752-758.
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Jens F. Rehfeld. (2015) Gastrointestinal hormone research – with a Scandinavian annotation. Scandinavian Journal of Gastroenterology 50:6, pages 668-679.
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Helge L Waldum, Per M Kleveland & Reidar Fossmark. (2015) Upper gastrointestinal physiology and diseases. Scandinavian Journal of Gastroenterology 50:6, pages 649-656.
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Helge L. Waldum, Gunnar Qvigstad, Reidar Fossmark, Per M. Kleveland & Arne K. Sandvik. (2010) Rebound acid hypersecretion from a physiological, pathophysiological and clinical viewpoint. Scandinavian Journal of Gastroenterology 45:4, pages 389-394.
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Helge L. Waldum, Per M. Kleveland, Eiliv Brenna, Ingunn Bakke, Gunnar Qvigstad, Tom Chr. Martinsen, Reidar Fossmark, Bjørn I. Gustafsson & Arne K. Sandvik. (2009) Interactions between gastric acid secretagogues and the localization of the gastrin receptor. Scandinavian Journal of Gastroenterology 44:4, pages 390-393.
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Arne K Sandvik, Helge L Waldum & Eiliv Brenna. (2002) Long-term safety of proton pump inhibitors: risks of gastric neoplasia and infections. Expert Opinion on Drug Safety 1:1, pages 29-38.
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H. Watanabe, T. Mochizuki & K. Maeyama. (1996) Transient Increase of Blood Histamine Level Induced by Pentagastrin Continuous Monitoring by in vivo Microdialysis. Scandinavian Journal of Gastroenterology 31:12, pages 1144-1150.
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Helge L. Waldum, Arne K. Sandvik, Unni Syversen & Eiliv Brenna. (1993) The Enterochromaffin-Like (ECL) Cell Physiological and pathophysiological role. Acta Oncologica 32:2, pages 141-147.
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Y. Tielemans, D. Chen, F. Sundler, R. Håkanson & G. Willems. (1992) Reversibility of the Cell Kinetic Changes Induced by Omeprazole in the Rat Oxyntic Mucosa: An Autoradiographic Study Using Tritiated Thymidine. Scandinavian Journal of Gastroenterology 27:2, pages 155-160.
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H. L. Waldum, M. Mignon, A. K. Sandvik & S. Bonfils. (1992) Biologic and Immunologic Gastrin Activity in Serum of Patients with Gastrinoma. Bioassay of Gastrin Activity in Serum. Scandinavian Journal of Gastroenterology 27:12, pages 1039-1044.
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H. L. Waldum, E. Brenna, A. K. Sandvik & H. Petersen. (1991) Session 5: Trophic Effect of Histamine on the Stomach. Scandinavian Journal of Gastroenterology 26:sup180, pages 137-142.
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H. L. Waldum, A. K. Sandvik, E. Brenna & B. Schulze Søgnen. (1991) Radioimmunoassay of Histamine. Scandinavian Journal of Gastroenterology 26:sup180, pages 32-39.
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E. Brenna, R. Håkanson, F. Sundler, A. K. Sandvik & H. L. Waldum. (1991) The Effect of Omeprazole-Induced Hypergastrinemia on the Oxyntic Mucosa of Mastomys. Scandinavian Journal of Gastroenterology 26:6, pages 667-672.
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Articles from other publishers (23)

Helge Waldum. 2020. Hormonal Signaling in Biology and Medicine. Hormonal Signaling in Biology and Medicine 341 359 .
Helge L. Waldum, Øystein F. Sørdal & Patricia G. Mjønes. (2019) The Enterochromaffin-like [ECL] Cell—Central in Gastric Physiology and Pathology. International Journal of Molecular Sciences 20:10, pages 2444.
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Michaël Rochoy, Sébastien Dubois, Raymond Glantenet, Sophie Gautier & Marc Lambert. (2018) Le rebond d’acidité gastrique après arrêt d’un inhibiteur de la pompe à protons : revue narrative de littérature. Therapies 73:3, pages 237-246.
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Kristin M. Aasarød, Astrid K. Stunes, Mats P. Mosti, Masoud Ramezanzadehkoldeh, Bjørn I. Viggaklev, Janne E. Reseland, Bjørn H. Skallerud, Reidar Fossmark & Unni Syversen. (2016) Effects of the Histamine 1 Receptor Antagonist Cetirizine on the Osteoporotic Phenotype in H + /K + ATPase Beta Subunit KO Mice . Journal of Cellular Biochemistry 117:9, pages 2089-2096.
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H. L. Waldum, Ø. Hauso & R. Fossmark. (2014) The regulation of gastric acid secretion - clinical perspectives. Acta Physiologica 210:2, pages 239-256.
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TD Barrett, G Lagaud, P Wagaman, JM Freedman, W Yan, L Andries, MC Rizzolio, MF Morton & NP Shankley. (2012) The cholecystokinin CCK2 receptor antagonist, JNJ-26070109, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat. British Journal of Pharmacology 166:5, pages 1684-1693.
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Helge L Waldum, Arne K Sandvik, Øyvind Hauso, Gunnar Qvigstad & Reidar Fossmark. (2012) Withdrawing PPI Therapy: Response to Metz et al.. American Journal of Gastroenterology 107:2, pages 325-326.
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Helge L. Waldum, Tom C. Martinsen, Øyvind Hauso & Gunnar Qvigstad. (2010) Oral proton-pump inhibitors and step-down therapy for nonulcer dyspepsia: is this the right approach?. Therapeutic Advances in Gastroenterology 3:2, pages 73-76.
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Reidar Fossmark. (2008) Gastric cancer: Animal studies on the risk of hypoacidity and hypergastrinemia. World Journal of Gastroenterology 14:11, pages 1646.
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R. Fossmark & H. Waldum. (2007) Rebound acid hypersecretion. Alimentary Pharmacology & Therapeutics 25:8, pages 999-1000.
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C. SCARPIGNATO & I. PELOSINI. (2006) Review article: the opportunities and benefits of extended acid suppression. Alimentary Pharmacology and Therapeutics 23:s2, pages 23-34.
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Gunnar Qvigstad & Helge Waldum. (2004) Rebound Hypersecretion after Inhibition of Gastric Acid Secretion. Basic & Clinical Pharmacology & Toxicology 94:5, pages 202-208.
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Giuseppina Morini, Daniela Grandi & Walter Schunack. (2002) Ligands for histamine H 3 receptors modulate cell proliferation and migration in rat oxyntic mucosa . British Journal of Pharmacology 137:2, pages 237-244.
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Sotirios Kolivas, Renee Dow, Ren Jie, Graham S Baldwin & Arthur Shulkes. (2008) Quantitative measurement of mRNA coding for the receptors controlling acid secretion in the ovine fundus and antrum by using RT‐PCR. Journal of Gastroenterology and Hepatology 15:11, pages 1257-1266.
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Sotirios Kolivas, Renee Dow, Ren Jie, Graham S Baldwin & Arthur Shulkes. (2000) Quantitative measurement of mRNA coding for the receptors controlling acid secretion in the ovine fundus and antrum by using RT-PCR 1. Journal of Gastroenterology and Hepatology 15:11, pages 1257-1266.
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Bakke, Qvigstad, Brenna, Sandvik & Waldum. (2001) Gastrin has a specific proliferative effect on the rat enterochromaffin‐like cell, but not on the parietal cell: A study by elutriation centrifugation. Acta Physiologica Scandinavica 169:1, pages 29-37.
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Waldum & Brenna. (2000) Personal review: is profound acid inhibition safe?. Alimentary Pharmacology & Therapeutics 14:1, pages 15-22.
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QVIGSTAD, BJØRGAAS, EIDE, SANDVIK & WALDUM. (2001) Vagal stimulation augments maximal (penta) gastrin‐stimulated acid secretion in humans. Acta Physiologica Scandinavica 165:3, pages 277-281.
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Hiroyuki MIKI, Hirotaka YAMADA, Nozomi YOSHIKAWA & Keiji MITAMURA. (1999) Effect of Omeprazole Ingestion on Healing of Gastric Ulcers and Serum Gastrin Concentration in Rats. The Showa University Journal of Medical Sciences 11:2, pages 105-114.
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I Scott, S.M Hodgkinson, D.E.B Lawton, S Khalaf, G.W Reynolds, W.E Pomroy & H.V Simpson. (1998) Infection of sheep with adult and larval Ostertagia circumcincta: gastrin. International Journal for Parasitology 28:9, pages 1393-1401.
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I Scott, S.M Hodgkinson, S Khalaf, D.E.B Lawton, M.G Collett, G.W Reynolds, W.E Pomroy & H.V Simpson. (1998) Infection of sheep with adult and larval Ostertagia circumcincta: abomasal morphology. International Journal for Parasitology 28:9, pages 1383-1392.
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H. L. WALDUM, E. BRENNA, P. M. KLEVELAND, A. K. SANDVIK & U. SYVERSEN. (2007) Review article: the use of gastric acid‐inhibitory drugs—physiological and pathophysiological considerations. Alimentary Pharmacology & Therapeutics 7:6, pages 589-596.
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E. BRENNA, H. L. WALDUM, A. K. SANDVIK, B. SCHULZE SØGNEN & A. KRISTENSEN. (2007) Effects on the rat oxyntic mucosa of the histamine 2 ‐antagonist loxtidine and the H + , K + ‐ATPase inhibitor omepvazole . Alimentary Pharmacology & Therapeutics 6:3, pages 335-349.
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