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Scandinavian Journal of Gastroenterology Volume 27, 1992 - Issue 3
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Original Article

Cimetidine On-Demand in Dyspepsia Experience with Randomized Controlled Single-Subject Trials

T. Johannessen Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
,
H. Petersen Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
,
P. Kristensen Dept. of Medicine, Trondheim Regional and University Hospital, Trondheim, Norway
,
D. Fosstvedt Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
,
P. M. Kleveland Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
,
J. Dybdahl & Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
&
I. Løge Dept. of Community Medicine and General Practice, University of Trondheim, and Section of Gastroenterology, Trondheim, Norway
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Pages 189-195 | Received 23 Aug 1991, Accepted 14 Oct 1991, Published online: 08 Jul 2009

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P. G. Farup, S. Wetterhus, M. Osnes & K. Ulshagen. (1997) Ranitidine Effectively Relieves Symptoms in a Subset of Patients with Functional Dyspepsia. Scandinavian Journal of Gastroenterology 32:8, pages 755-759.
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P. G. Farup, Ø Hovde & O. Breder. (1995) Are Frequent Short Gastro-Oesophageal Reflux Episodes the Cause of Symptoms in Patients with Non-Ulcer Dyspepsia Responding to Treatment with Ranitidine?. Scandinavian Journal of Gastroenterology 30:9, pages 829-832.
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Terje Johannessen, Hermod Petersen, Pål Kristensen, Per Martin Kleveland, Jan Dybdahl, Arne K. Sandvik, Eiliv Brenna And & Helge Waldum. (1993) The intensity and variability of symptoms in dyspepsia. Scandinavian Journal of Primary Health Care 11:1, pages 50-55.
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Articles from other publishers (20)

Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas & Jose De la Hoz-Valle. (2019) A Randomized Placebo-Controlled N -of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease . Canadian Journal of Gastroenterology and Hepatology 2019, pages 1-9.
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Larissa Shamseer, Margaret Sampson, Cecilia Bukutu, Christopher H. Schmid, Jane Nikles, Robyn Tate, Bradley C. Johnston, Deborah Zucker, William R. Shadish, Richard Kravitz, Gordon Guyatt, Douglas G. Altman, David Moher, Sunita Vohra, Douglas G. Altman, Cecilia Bukutu, Jocalyn Clark, Elise Cogo, Nicole B. Gabler, Gordon Guyatt, Richard Kravitz, Janine Janosky, Bradley C. Johnston, Bob Li, Jeff Mahon, Robin Marles, David Moher, Jane Nikles, Margaret Sampson, Christopher H. Schmid, William R. Shadish, Larissa Shamseer, Robyn Tate, Sunita Vohra & Deborah Zucker. (2016) CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration. Journal of Clinical Epidemiology 76, pages 18-46.
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Deborah R. Zucker, Robin Ruthazer & Christopher H. Schmid. (2010) Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: methodologic considerations. Journal of Clinical Epidemiology 63:12, pages 1312-1323.
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Deborah R. Zucker, Aneet Deo & Christopher H. Schmid. (2010) Dialysis Research and N-of-1 Trials: Made for Each Other?. American Journal of Kidney Diseases 55:4, pages 635-638.
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R Jones. (2008) Primary care research and clinical practice: gastroenterology. Postgraduate Medical Journal 84:995, pages 454-458.
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Jorgen Urnes, Per G. Farup, Stian Lydersen & Hermod Petersen. (2007) Patient education in gastro-oesophageal reflux disease: a randomized controlled trial. European Journal of Gastroenterology & Hepatology 19:12, pages 1104-1110.
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J. Zacny, M. Zamakhshary, I. Sketris & S. Veldhuyzen van Zanten. (2005) Systematic review: the efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients. Alimentary Pharmacology and Therapeutics 21:11, pages 1299-1312.
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L. G. Madsen, L. Wallin & P. Bytzer. (2004) Identifying response to acid suppressive therapy in functional dyspepsia using a random starting day trial - is gastro-oesophageal reflux important?. Alimentary Pharmacology & Therapeutics 20:4, pages 423-430.
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L. G. Madsen & P. Bytzer. (2002) Single subject trials as a research instrument in gastrointestinal pharmacology. Alimentary Pharmacology & Therapeutics 16:2, pages 189-196.
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H. A. Redstone, N. Barrowman & S. J. O. Veldhuyzen Van Zanten. (2001) H 2 -receptor antagonists in the treatment of functional (nonulcer) dyspepsia: a meta-analysis of randomized controlled clinical trials . Alimentary Pharmacology & Therapeutics 15:9, pages 1291-1299.
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Peter Bytzer & Nicholas J. Talley. (2001) Current indications for acid suppressants in dyspepsia. Best Practice & Research Clinical Gastroenterology 15:3, pages 385-400.
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P. Bytzer, J. M. Hansen, S. Rune, O. Bonnevie, H. Breinstrup, P. Funch‐Jensen, P. Matzen, V. Meineche‐Schmidt & O. B. Schaffalitzky De Muckadell. (2001) Identifying responders to acid suppression in dyspepsia using a random starting day trial. Alimentary Pharmacology & Therapeutics 14:11, pages 1485-1494.
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Christopher J Hawkey. (1999) Irritable bowel syndrome clinical trial design: future needs. The American Journal of Medicine 107:5, pages 98-102.
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Mark Pimentel & Henry C. Lin. 1999. Gastrointestinal Motility. Gastrointestinal Motility 285 294 .
P K Blustein, P L Beck, J B Meddings, G M A Van Rosendaal, R J Bailey, E Lalor, A B R Thomson, M J Verhoef & L R Sutherland. (1998) The utility of endoscopy in the management of patients with gastroesophageal reflux symptoms. American Journal of Gastroenterology 93:12, pages 2508-2512.
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J. S. Finney, N. Kinnersley, M. Hughes, C. G. O'Bryan-Tear & J. Lothian. (1998) Meta-Analysis of Antisecretory and Gastrokinetic Compounds in Functional Dyspepsia. Journal of Clinical Gastroenterology 26:4, pages 312-320.
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NICHOLAS J TALLEY, SK LAM, KL GOH & KM FOCK. (2008) Management guidelines for uninvestigated and functional dyspepsia in the Asia‐Pacific region: First Asian Pacific working party on functional dyspepsia. Journal of Gastroenterology and Hepatology 13:4, pages 335-353.
Crossref
Joseph Herman. (1996) The Law of Halves. Journal of Clinical Epidemiology 49:5, pages 595-598.
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GP Rubin, B Contractor & MG Bramble. (1995) THE USE OF LONG‐TERM ACID‐SUPPRESSION THERAPY. International Journal of Clinical Practice 49:3, pages 119-120.
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Michael G. Byas-Smith, Mitchell B. Max, Joanne Muir & Albert Kingman. (1995) Transdermal clonidine compared to placebo in painful diabetic neuropathy using a two-stage ‘enriched enrollment’ design. Pain 60:3, pages 267-274.
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