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Original Article

Procoagulant and Prothrombotic Responses of Human Endothelium to Indomethacin and Endotoxin in Vitro Relevance to Non-Steroidal Anti-Inflammatory Drug Enteropathy

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Pages 25-32 | Received 04 Dec 1993, Accepted 04 May 1994, Published online: 08 Jul 2009

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Tsutomu Yoshihara, Yosuke Oikawa, Takayuki Kato, Takaomi Kessoku, Takashi Kobayashi, Shingo Kato, Noboru Misawa, Keiichi Ashikari, Akiko Fuyuki, Hidenori Ohkubo, Takuma Higurashi, Yoko Tateishi, Yoshiki Tanaka, Shunji Nakajima, Hiroshi Ohno, Koichiro Wada & Atsushi Nakajima. (2020) The protective effect of Bifidobacterium bifidum G9-1 against mucus degradation by Akkermansia muciniphila following small intestine injury caused by a proton pump inhibitor and aspirin. Gut Microbes 11:5, pages 1385-1404.
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Stefania Mantarro, Marco Tuccori, Giuseppe Pasqualetti, Sara Tognini, Sabrina Montagnani, Fabio Monzani & Corrado Blandizzi. (2012) Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient. BMC Geriatrics 12:1.
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Abdul Wadood, Syed Abid Ali, Rabia Sattar, Muhammad Arif Lodhi & Zaheer Ul-Haq. (2012) A Novel Pharmacophore Model to Identify Leads for Simultaneous Inhibition of Anti-coagulation and Anti-inflammatory Activities of Snake Venom Phospholipase A2. Chemical Biology & Drug Design 79:4, pages 431-441.
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Nagendra Singh, Ramasamy Prem Kumar, Sanjit Kumar, Sujata Sharma, Rafia Mir, Punit Kaur, Alagiri Srinivasan & Tej P. Singh. (2009) Simultaneous inhibition of anti-coagulation and inflammation: crystal structure of phospholipase A 2 complexed with indomethacin at 1.4 Å resolution reveals the presence of the new common ligand-binding site . Journal of Molecular Recognition 22:6, pages 437-445.
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Ernst Eypasch, Edmund A.M. Neugebauer, F. Fischer, Hans Troidl, A.L. Blum, D. Collet, A. Cuschieri, B. Dallemagne, H. Feussner, K.-H. Fuchs, H. Glise, C.K. Kum, T. Lerut, L. Lundell, H.E. Myrvold, A. Peracchia, H. Petersen & J.J.B. van Lanschot. 2006. EAES Guidelines for Endoscopic Surgery. EAES Guidelines for Endoscopic Surgery 97 124 .
Karna Dev Bardhan. (2003) Intermittent and on-Demand Use of Proton Pump Inhibitors in The Management of Symptomatic Gastroesophageal Reflux Disease. American Journal of Gastroenterology 98, pages S40-S48.
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Nicholas J. Talley, Thomas L. Venables, Jonathan R. B. Green, David Armstrong, Kevin P. J. O'Kane, Mustafa Giaffer, Karna D. Bardhan, Rolf G. S. Carlsson, Samuel Chen & Göran S. Hasselgren. (2002) Esomeprazole 40 mg and 20 mg is efficacious in the long-term management of patients with endoscopy-negative gastro-oesophageal reflux disease: a placebo-controlled trial of on-demand therapy for 6 months. European Journal of Gastroenterology & Hepatology 14:8, pages 857-863.
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Joseph Romagnuolo, Michael A. Meier & Daniel C. Sadowski. (2002) Medical or Surgical Therapy for Erosive Reflux Esophagitis. Annals of Surgery 236:2, pages 191-202.
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Taylor Brandão Schnaider, Alcino Lázaro da Silva, Miriam de Fátima Brasil Engelman, Yara Juliano, Neil Ferreira Novo, Gabrielle Sormanti Schnaider & Caroline Sormanti Schnaider. (2002) Estudo morfométrico do efeito do tenoxicam com água bidestilada ou com cloreto de sódio a 0,9% no endotélio venoso, em coelhos. Acta Cirurgica Brasileira 17:2, pages 122-129.
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Taylor Brandão Schnaider, Carlos Henrique Vianna de Andrade, Yara Juliano, Neil Ferreira Novo, Miriam de Fátima Brasil Engelman, Gabrielle Sormanti Schnaider & Caroline Sormanti Schnaider. (2001) Estudo morfométrico do efeito do Tenoxicam e do seu diluente no endotélio venoso, em coelhos. Acta Cirurgica Brasileira 16:3, pages 122-127.
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Omar M.E. Abdel-Salam, József Czimmer, András Debreceni, János Szolcsányi & Gyula Mózsik. (2001) Gastric mucosal integrity: gastric mucosal blood flow and microcirculation. An overview. Journal of Physiology-Paris 95:1-6, pages 105-127.
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Taylor Brandão Schnaider, Carlos Henrique Vianna de Andrade, Yara Juliano, Neil Ferreira Novo, Miriam de Fátima Brasil Engelman, Gabrielle Sormanti Schnaider & Caroline Sormanti Schnaider. (2000) Estudo histopatológico do efeito do tenoxicam e do seu diluente no endotélio venoso, em coelhos. Acta Cirurgica Brasileira 15:2, pages 118-123.
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Hideki Koga, Kunihiko Aoyagi, Takayuki Matsumoto, Mitsuo Iida & Masatoshi Fujishima. (1999) Experimental enteropathy in athymic and euthymic rats: synergistic role of lipopolysaccharide and indomethacin. American Journal of Physiology-Gastrointestinal and Liver Physiology 276:3, pages G576-G582.
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O. M. E. Abdel Salam, J. Szolcsányi & Gy. Mózsik. 1997. Cell Injury and Protection in the Gastrointestinal Tract. Cell Injury and Protection in the Gastrointestinal Tract 95 105 .
O.M.E Abdel-Salam, J Szolcsányi & G Mózsik. (1996) Differences in action of topical and systemic cysteamine on gastric blood flow, gastric acid secretion and gastric ulceration in the rat. Journal of Physiology-Paris 90:2, pages 63-73.
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