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Research Article

What should be the optimal cut-off of serum 1,3-β-d-glucan for the detection of invasive pulmonary aspergillosis in patients with haematological malignancies?

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Pages 330-336 | Received 29 Jul 2011, Accepted 24 Oct 2011, Published online: 21 Dec 2011

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Guanghui Huang, Xin Ye, Xia Yang, Chuntang Wang, Licheng Zhang, Guangdong Ji, Kaixian Zhang, Huili Wang, Aimin Zheng, Wenhong Li, Jiao Wang, Xiaoying Han, Zhigang Wei, Min Meng & Yang Ni. (2018) Invasive pulmonary aspergillosis secondary to microwave ablation: a multicenter retrospective study. International Journal of Hyperthermia 35:1, pages 71-78.
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Daniele Roberto Giacobbe, Valerio Del Bono, Claudio Viscoli & Malgorzata Mikulska. (2017) Use of 1,3-β-D-glucan in invasive fungal diseases in hematology patients. Expert Review of Anti-infective Therapy 15:12, pages 1101-1112.
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Articles from other publishers (18)

Katherine Garnham, Catriona L. Halliday, Neela J. Rai, Menuk Jayawardena, Tasnim Hasan, Jen Kok, Vineet Nayyar, David J. Gottlieb, Nicole M. Gilroy & Sharon C.‐A. Chen. (2022) Introducing 1,3‐beta‐ d ‐glucan for screening and diagnosis of invasive fungal diseases in Australian high‐risk haematology patients: is there a clinical benefit? . Internal Medicine Journal 52:3, pages 426-435.
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Karl Dichtl, Johannes Forster, Steffen Ormanns, Heidi Horns, Sebastian Suerbaum, Ulrich Seybold & Johannes Wagener. (2020) Comparison of β-D-Glucan and Galactomannan in Serum for Detection of Invasive Aspergillosis: Retrospective Analysis with Focus on Early Diagnosis. Journal of Fungi 6:4, pages 253.
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Sandra K White, Robert L Schmidt, Brandon S Walker & Kimberly E Hanson. (2020) (1→3)-β-D-glucan testing for the detection of invasive fungal infections in immunocompromised or critically ill people. Cochrane Database of Systematic Reviews 2020:7.
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Sandra K White, Brandon S Walker, Kimberley E Hanson & Robert L Schmidt. (2019) Diagnostic Accuracy of β- d -Glucan (Fungitell) Testing Among Patients With Hematologic Malignancies or Solid Organ Tumors . American Journal of Clinical Pathology 151:3, pages 275-285.
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Lu Xiaoling, Tang Tingyu, Hu Caibao, Zhao Tian & Chen Changqin. (2018) Diagnostic efficacy of serum 1,3-β-D-glucan for invasive fungal infection: An update meta-analysis based on 37 case or cohort studies. Open Medicine 13:1, pages 329-337.
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R. Dobias, P. Jaworska, H. Tomaskova, M. Kanova, P. Lyskova, Z. Vrba, C. Holub, L. Svobodová, P. Hamal & M. Raska. (2018) Diagnostic value of serum galactomannan, (1,3)-β- d -glucan, and Aspergillus fumigatus -specific IgA and IgG assays for invasive pulmonary aspergillosis in non-neutropenic patients . Mycoses 61:8, pages 576-586.
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Mashook Ali. 2017. Molecular Markers in Mycology. Molecular Markers in Mycology 225 242 .
G. Metan & F. Elmali. (2016) The influence of the control group characteristics for the diagnostic performance of 1,3-beta-D-glucan in invasive aspergillosis. Journal de Mycologie Médicale 26:4, pages 408-410.
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Gülçin BÖLÜK, Esra KAZAK, Fahir ÖZKALEMKAŞ, Beyza ENER, Halis AKALIN, Harun AĞCA, Yıldız OKUTURLAR, Kürşad KESKİN, Başak BURGAZLIOĞLU & Rıdvan ALİ. (2016) Comparison of galactomannan, beta-D-glucan, and Aspergillus DNA in sera of high-risk adult patients with hematological malignancies for the diagnosis of invasive aspergillosis. TURKISH JOURNAL OF MEDICAL SCIENCES 46, pages 335-342.
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P. Lewis White, John R. Wingard, Stéphane Bretagne, Jürgen Löffler, Thomas F. Patterson, Monica A. Slavin, Rosemary A. Barnes, Peter G. Pappas & J. Peter Donnelly. (2015) Aspergillus Polymerase Chain Reaction: Systematic Review of Evidence for Clinical Use in Comparison With Antigen Testing . Clinical Infectious Diseases 61:8, pages 1293-1303.
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Gökhan Metan, Zeynep Türe, Çiğdem Pala, Leylagül Kaynar, Afra Yıldırım, Ferhan Elmalı, Nuri Tutar, Nuran Yozgat & Bülent Eser. (2014) A Single Center Experience for Antifungal Prophylaxis in Patients with Acute Myelogenous Leukemia. Indian Journal of Hematology and Blood Transfusion 31:3, pages 339-345.
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Anshula Ambasta, Julie Carson & Deirdre L Church. (2015) The use of biomarkers and molecular methods for the earlier diagnosis of invasive aspergillosis in immunocompromised patients. Medical Mycology 53:6, pages 531-557.
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Song He, Ju-Ping Hang, Ling Zhang, Fang Wang, De-Chun Zhang & Fang-Hong Gong. (2015) A systematic review and meta-analysis of diagnostic accuracy of serum 1,3-β-d-glucan for invasive fungal infection: Focus on cutoff levels. Journal of Microbiology, Immunology and Infection 48:4, pages 351-361.
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C. Farina, G. Lombardi, S. Andreoni, E. Manso, S. Perin, D. Panellis, P. Fazii, M. Conte, S. Sanna, P. Pini & E. Blasi. (2014) Routine Use of a Protease Zymogen-Based Colorimetric Assay for the Detection of Beta-Glucan and its Role in Clinical Practice. International Journal of Immunopathology and Pharmacology 27:4, pages 661-668.
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Marios Arvanitis, Theodora Anagnostou, Beth Burgwyn Fuchs, Angela M. Caliendo & Eleftherios Mylonakis. (2014) Molecular and Nonmolecular Diagnostic Methods for Invasive Fungal Infections. Clinical Microbiology Reviews 27:3, pages 490-526.
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Xuejiu Cai, Wentao Ni, Chuanqi Wei & Junchang Cui. (2014) Diagnostic Value of the Serum Galactomannan and (1, 3)-β-D-glucan Assays for Invasive Pulmonary Aspergillosis in Non-neutropenic Patients. Internal Medicine 53:21, pages 2433-2437.
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Nuri Tutar, Gokhan Metan, Ayşe Nedret Koç, Insu Yilmaz, Ilkay Bozkurt, Zuhal Ozer Simsek, Hakan Buyukoglan, Asiye Kanbay, Fatma Sema Oymak, Inci Gulmez & Ramazan Demir. (2013) Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Multidisciplinary Respiratory Medicine 8:1.
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Elitza S. Theel & Christopher D. Doern. (2013) Point-Counterpoint: β- d -Glucan Testing Is Important for Diagnosis of Invasive Fungal Infections . Journal of Clinical Microbiology 51:11, pages 3478-3483.
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