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Original Article

Imipenem/cilastatin (1.5 g daily) versus Meropenem (3.0 g daily) in Patients with Intra-abdominal Infections: Results of a Prospective, Randomized, Multicentre Trial

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Pages 503-508 | Received 07 Apr 1997, Accepted 08 Jul 1997, Published online: 08 Jul 2009

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Ioannis P Kioumis, Joseph L Kuti & David P Nicolau. (2007) Intra-abdominal infections: considerations for the use of the carbapenems. Expert Opinion on Pharmacotherapy 8:2, pages 167-182.
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Ceyda Karadeniz, Aynur Oguz, Berna Canter & Ayse Serdaroglu. (2000) INCIDENCE OF SEIZURES IN PEDIATRIC CANCER PATIENTS TREATED WITH IMIPENEM/CILASTATIN. Pediatric Hematology and Oncology 17:7, pages 585-590.
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Katerina Tori, Giannoula S. Tansarli, Diane M. Parente, Markos Kalligeros, Panayiotis D. Ziakas & Eleftherios Mylonakis. (2020) The cost-effectiveness of empirical antibiotic treatments for high-risk febrile neutropenic patients. Medicine 99:20, pages e20022.
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Lingyuan Chen, Xueyan Liang, Junsong Jiang, Xianshu Li & Yan Li. (2019) Carbapenems vs tigecycline for the treatment of complicated intra-abdominal infections. Medicine 98:40, pages e17436.
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Joan P. Cannon, Todd A. Lee, Nina M. Clark, Paul Setlak & Shellee A. Grim. (2014) The risk of seizures among the carbapenems: a meta-analysis. Journal of Antimicrobial Chemotherapy 69:8, pages 2043-2055.
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Kemal Turkyilmaz, Ali Kurt, Aziz R. Dilek, Berrak Sekeryapan & Ayse Erturk. (2012) A case of suture-related bacterial keratitis and its treatment with topical imipenem. Journal of Ocular Biology, Diseases, and Informatics 4:4, pages 141-144.
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John F. Mohr III. (2008) Update on the Efficacy and Tolerability of Meropenem in the Treatment of Serious Bacterial Infections. Clinical Infectious Diseases 47:s1, pages S41-S51.
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P. Kujath, M. Hoffmann & A. Rodloff. (2008) Antibiotika- und Pilztherapie bei intraabdominellen InfektionenAntimicrobial and antimycotic therapy of intra-abdominal infections. Der Chirurg 79:4, pages 295-305.
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Antonio Basoli, Piero Chirletti, Ercole Cirino, Nicola G. D’Ovidio, Giovanni Battista Doglietto, Domenico Giglio, Stefano M. Giulini, Alberto Malizia, Mario Taffurelli, Jelena Petrovic & Maurizio Ecari. (2007) A Prospective, Double-Blind, Multicenter, Randomized Trial Comparing Ertapenem 3 Vs ≥5 Days in Community-Acquired Intraabdominal Infection. Journal of Gastrointestinal Surgery 12:3, pages 592-600.
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M.-C. Monteiro, A. Danielou, Y. Piemont, Y. Hansmann & S. Rohr. (2007) Prélèvements microbiologiques et traitements antibiotiques probabilistes des péritonites secondaires communautaires. Journal de Chirurgie 144:6, pages 486-491.
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T. L. Husted, E. W. Mueller, T. M. Lasky, M. A. Jafri & J. S. Solomkin. 2007. Infectious Diseases in Critical Care. Infectious Diseases in Critical Care 494 508 .
Steven J. Edwards, Helen E. Campbell & Jonathan M. Plumb. (2006) Cost-utility analysis comparing meropenem with imipenem plus cilastatin in the treatment of severe infections in intensive care. The European Journal of Health Economics 7:1, pages 72-78.
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Jose M. TelladoSamuel E. Wilson. (2005) Empiric Treatment of Nosocomial Intra-Abdominal Infections: A Focus on the Carbapenems. Surgical Infections 6:3, pages 329-343.
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Peng F Wong, Andrew D Gilliam, Senthil Kumar, Jonathan Shenfine, Graham N O'Dair & David J Leaper. (2005) Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults. Cochrane Database of Systematic Reviews.
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Peter Fomin, Mircea Beuran, Audrius Gradauskas, Giedrius Barauskas, Alexey Datsenko, Nathalie Dartois, Evelyn Ellis-Grosse & Evan Loh. (2005) Tigecycline is efficacious in the treatment of complicated intra-abdominal infections. International Journal of Surgery 3:1, pages 35-47.
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Joseph S. Solomkin, John E. Mazuski, Ellen J. Baron, Robert G. Sawyer, Avery B. Nathens, Joseph T. DiPiro, Timothy Buchman, E. Patchen Dellinger, John Jernigan, Sherwood Gorbach, Anthony W. Chow & John Bartlett. (2003) Guidelines for the Selection of Anti-infective Agents for Complicated Intra-abdominal Infections. Clinical Infectious Diseases 37:8, pages 997-1005.
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John E. Mazuski, Robert G. Sawyer, Avery B. Nathens, Joseph T. DiPiro, Moshe Schein, Kenneth A. Kudsk & Charles Yowler. (2002) The Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-Abdominal Infections: Evidence for the Recommendations. Surgical Infections 3:3, pages 175-233.
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John E. Mazuski, Robert G. Sawyer, Avery B. Nathens, Joseph T. DiPiro, Moshe Schein, Kenneth A. Kudsk & Charles Yowler. (2002) The Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-Abdominal Infections: An Executive Summary. Surgical Infections 3:3, pages 161-173.
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Per Sandven, Hanne Qvist, Eva Skovlund & Karl E. Giercksky. (2002) Significance of Candida recovered from intraoperative specimens in patients with intra-abdominal perforations. Critical Care Medicine 30:3, pages 541-547.
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Eva Susanne Dietrich, Bj??rn Schubert, Winfried Ebner & Franz Daschner. (2001) Cost Efficacy of Tazobactam/Piperacillin versus Imipenem/Cilastatin in the Treatment of Intra-Abdominal Infection. PharmacoEconomics 19:1, pages 79-94.
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Matthew N. Lowe & Harriet M. Lamb. (2000) Meropenem. Drugs 60:3, pages 619-646.
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Lenore E. Asbel & Matthew E. Levison. (2000) CEPHALOSPORINS, CARBAPENEMS, AND MONOBACTAMS. Infectious Disease Clinics of North America 14:2, pages 435-447.
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Giorgio Zanetti, Stephan Jürgen Harbarth, Andrej Trampuz, Marcus Ganeo, François Mosimann, Roland Chautemps, Pierre Morel, Daniel Lew, Werner Zimmerli, Jochen Lange & Michel Glauser. (1999) Meropenem (1.5 g/day) is as effective as imipenem/cilastatin (2 g/day) for the treatment of moderately severe intra-abdominal infections. International Journal of Antimicrobial Agents 11:2, pages 107-113.
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Toni Darville. (1999) Imipenem and meropenem. Seminars in Pediatric Infectious Diseases 10:1, pages 38-44.
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Barry Sieger. (1998) Comparisons of Seizure Incidence and Adverse Experiences Between Imipenem and Meropenem. Critical Care Medicine 26:8, pages 1465-1466.
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Jennifer Schranz. (1998) Comparisons of Seizure Incidence and Adverse Experiences Between Imipenem and Meropenem. Critical Care Medicine 26:8, pages 1464-1465.
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