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Scandinavian Journal of Urology and Nephrology Volume 43, 2009 - Issue 5
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Clinical Research Articles

Cranberry juice for the prevention of recurrent urinary tract infections: A randomized controlled trial in children

Pietro Ferrara Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, ItalyCorrespondence[email protected]
,
Luciana Romaniello Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, Italy
,
Ottavio Vitelli Campus Bio-Medico University, Rome, Italy
,
Antonio Gatto Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, Italy
,
Martina Serva Campus Bio-Medico University, Rome, Italy
&
Luigi Cataldi Department of Pediatrics, Catholic University, A. Gemelli Hospital, Rome, Italy
Pages 369-372 | Received 30 Jan 2009, Published online: 18 Nov 2009

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Hye Won Kim & Min Suk Rhee. (2018) Response surface modeling of reductions in uropathogenic Escherichia coli biofilms on silicone by cranberry extract, caprylic acid, and thymol. Biofouling 34:6, pages 710-717.
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Rainer Nowack & Rainer Birck. (2015) Cranberry products in the prevention of urinary tract infections: examining the evidence. Botanics: Targets and Therapy 5, pages 45-54.
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Muhammad Awais, Abdul Rehman, Noor Ul-Ain Baloch, Farid Khan & Naseer Khan. (2015) Evaluation and management of recurrent urinary tract infections in children: state of the art. Expert Review of Anti-infective Therapy 13:2, pages 209-231.
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Jose Uberos, Mercedes Nogueras-Ocana, Verónica Fernandez-Puentes, Rocio Rodriguez-Belmonte, Eduardo Narbona-López, Antonio Molina-Carballo & Antonio Munoz-Hoyos. (2012) Cranberry syrup vs trimethoprim in the prophylaxis of recurrent urinary tract infections among children: a controlled trial. Open Access Journal of Clinical Trials 4, pages 31-38.
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Articles from other publishers (59)

Catalin Tufanaru, Didi Surian, Anna Mae Scott, Paul Glasziou & Enrico Coiera. (2024) The 2-week systematic review (2weekSR) method was successfully blind-replicated by another team: a case study. Journal of Clinical Epidemiology 165, pages 111197.
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Gabrielle Williams, Christopher I Stothart, Deirdre Hahn, Jacqueline H Stephens, Jonathan C Craig & Elisabeth M Hodson. (2023) Cranberries for preventing urinary tract infections. Cochrane Database of Systematic Reviews 2023:11.
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Tess E Cooper, Rabia Khalid, Samuel Chan, Jonathan C Craig, Carmel M Hawley, Martin Howell, David W Johnson, Allison Jaure, Armando Teixeira-Pinto & Germaine Wong. (2023) Synbiotics, prebiotics and probiotics for people with chronic kidney disease. Cochrane Database of Systematic Reviews 2023:10.
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Gabrielle Williams, Deirdre Hahn, Jacqueline H Stephens, Jonathan C Craig & Elisabeth M Hodson. (2023) Cranberries for preventing urinary tract infections. Cochrane Database of Systematic Reviews 2023:4.
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Cecilia Bukutu & Sunita Vohra. 2023. Pediatric Kidney Disease. Pediatric Kidney Disease 1987 2018 .
Christina B. Ching. (2022) Non-antibiotic Approaches to Preventing Pediatric UTIs: a Role for D-Mannose, Cranberry, and Probiotics?. Current Urology Reports 23:6, pages 113-127.
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Paulina Wigner, Michał Bijak & Joanna Saluk-Bijak. (2022) Clinical Potential of Fruit in Bladder Cancer Prevention and Treatment. Nutrients 14:6, pages 1132.
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Jitendra Meena, Christy C. Thomas, Jogender Kumar, Sumantra Raut & Pankaj Hari. (2021) Non-antibiotic interventions for prevention of urinary tract infections in children: a systematic review and meta-analysis of randomized controlled trials. European Journal of Pediatrics 180:12, pages 3535-3545.
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Jia-yue Xia, Chao Yang, Deng-feng Xu, Hui Xia, Li-gang Yang & Gui-ju Sun. (2021) Consumption of cranberry as adjuvant therapy for urinary tract infections in susceptible populations: A systematic review and meta-analysis with trial sequential analysis. PLOS ONE 16:9, pages e0256992.
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Dipika Dabas. (2020) In vitro Evidence of Dose-dependent Decrease of Uropathogenic E. coli after Consuming Commercial Cranberry Capsules in Type 2 Diabetic Premenopausal Adult Women: A Literature Review. Journal of Health Sciences & Research 11:2, pages 58-63.
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Sarita Das. (2020) Natural therapeutics for urinary tract infections—a review. Future Journal of Pharmaceutical Sciences 6:1.
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Stylianos Vagios, Helai Hesham & Caroline Mitchell. (2020) Understanding the potential of lactobacilli in recurrent UTI prevention. Microbial Pathogenesis 148, pages 104544.
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Shaomin Zhao, Haiyan Liu & Liwei Gu. (2018) American cranberries and health benefits – an evolving story of 25 years. Journal of the Science of Food and Agriculture 100:14, pages 5111-5116.
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Anna Mae Scott, Justin Clark, Chris Del Mar & Paul Glasziou. (2020) Increased fluid intake to prevent urinary tract infections: systematic review and meta-analysis. British Journal of General Practice 70:692, pages e200-e207.
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R. Beetz. (2020) Ist die antibakterielle Langzeitprophylaxe immer noch alternativlos?Is there still no alternative to long-term antibacterial prophylaxis?. Der Urologe 59:3, pages 255-260.
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Thomas Brendler & Amy Howell. 2020. Medicinal and Aromatic Plants of North America. Medicinal and Aromatic Plants of North America 81 117 .
Néha Sihra, Anna Goodman, Rhana Zakri, Arun Sahai & Sachin Malde. (2018) Nonantibiotic prevention and management of recurrent urinary tract infection. Nature Reviews Urology 15:12, pages 750-776.
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Anyanwu Matthew, Nyan O, Gai B & Thompson D. (2018) HIV infection: the course and outcome of pregnancy in the Gambia between 2005 and June 2011. International Journal of Pregnancy & Child Birth 4:6.
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Niko Paalanne, Aleksi Husso, Jarmo Salo, Oskari Pieviläinen, Mysore V. Tejesvi, Pirjo Koivusaari, Anna Maria Pirttilä, Tytti Pokka, Sampo Mattila, Juha Jyrkäs, Ari Turpeinen, Matti Uhari, Marjo Renko & Terhi Tapiainen. (2018) Intestinal microbiome as a risk factor for urinary tract infections in children. European Journal of Clinical Microbiology & Infectious Diseases 37:10, pages 1881-1891.
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Zeynep Temiz & Ikbal Cavdar. (2018) The effects of training and the use of cranberry capsule in preventing urinary tract infections after urostomy. Complementary Therapies in Clinical Practice 31, pages 111-117.
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Juan Canales & Gabriel Rada. (2018) Are probiotics effective in preventing urinary tract infection?. Medwave 18:02, pages e7185-e7185.
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Hyun-Sop Choe, Seung-Ju Lee, Stephen S Yang, Ryoichi Hamasuna, Shingo Yamamoto, Yong-Hyun Cho & Tetsuro Matsumoto. (2018) Summary of the UAA-AAUS guidelines for urinary tract infections. International Journal of Urology 25:3, pages 175-185.
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Ângelo Luís, Fernanda Domingues & Luísa Pereira. (2017) Can Cranberries Contribute to Reduce the Incidence of Urinary Tract Infections? A Systematic Review with Meta-Analysis and Trial Sequential Analysis of Clinical Trials. Journal of Urology 198:3, pages 614-621.
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Tycho Jan Zuzak. (2016) Use of Complementary and Alternative Medicine by Children in Italy - A Status Quo. International Journal of Complementary & Alternative Medicine 4:1.
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DeAnn J Liska, Hua J Kern & Kevin C Maki. (2016) Cranberries and Urinary Tract Infections: How Can the Same Evidence Lead to Conflicting Advice?. Advances in Nutrition 7:3, pages 498-506.
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Prachi Gupta, Biqin Song, Catherine Neto & Terri A. Camesano. (2016) Atomic force microscopy-guided fractionation reveals the influence of cranberry phytochemicals on adhesion of Escherichia coli. Food & Function 7:6, pages 2655-2666.
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Cecilia Bukutu & Sunita Vohra. 2016. Pediatric Kidney Disease. Pediatric Kidney Disease 1949 1974 .
Elisabeth M. Hodson & Jonathan C. Craig. 2016. Pediatric Nephrology. Pediatric Nephrology 1695 1714 .
Erin M Schwenger, Aaron M Tejani & Peter S Loewen. (2015) Probiotics for preventing urinary tract infections in adults and children. Cochrane Database of Systematic Reviews 2015:12.
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Spencer H. Durham, Pamela L. Stamm & Lea S. Eiland. (2015) Cranberry Products for the Prophylaxis of Urinary Tract Infections in Pediatric Patients. Annals of Pharmacotherapy 49:12, pages 1349-1356.
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J. Uberos, R. Rodríguez-Belmonte, C. Rodríguez-Pérez, M. Molina-Oya, E. Blanca-Jover, E. Narbona-Lopez & A. Muñoz-Hoyos. (2015) Phenolic acid content and antiadherence activity in the urine of patients treated with cranberry syrup (Vaccinium macrocarpon) vs. trimethoprim for recurrent urinary tract infection. Journal of Functional Foods 18, pages 608-616.
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V. Fernández-Puentes, J. Uberos, R. Rodríguez-Belmonte, M. Nogueras-Ocaña, E. Blanca-Jover & E. Narbona-López. (2015) Eficacia y perfil de seguridad del arándano americano en lactantes y niños con infección urinaria recurrente. Anales de Pediatría 82:6, pages 397-403.
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V. Fernández-Puentes, J. Uberos, R. Rodríguez-Belmonte, M. Nogueras-Ocaña, E. Blanca-Jover & E. Narbona-López. (2015) Efficacy and safety profile of cranberry in infants and children with recurrent urinary tract infection. Anales de Pediatría (English Edition) 82:6, pages 397-403.
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Peter Marquardt, Karin Kaft & Karen Nieber. (2015) Clinical trials with herbal medicinal products in children: a literature analysisKlinische Studien mit pflanzlichen Arzneimitteln bei Kindern – eine Literaturrecherche. Wiener Medizinische Wochenschrift 165:11-12, pages 236-242.
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E. Gardner. (2014) The health properties of cranberry juice. Nutrition Bulletin 39:2, pages 223-230.
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D. M. B. T. Disaanayake, Joan Faoagali, Hans Laroo, Gerald Hancock & Michael Whitehouse. (2014) Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis. Inflammopharmacology 22:2, pages 73-77.
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H. S. Rane, S. M. Bernardo, A. B. Howell & S. A. Lee. (2013) Cranberry-derived proanthocyanidins prevent formation of Candida albicans biofilms in artificial urine through biofilm- and adherence-specific mechanisms. Journal of Antimicrobial Chemotherapy 69:2, pages 428-436.
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Elisabeth M. Hodson & Jonathan C. Craig. 2014. Pediatric Nephrology. Pediatric Nephrology 1 22 .
Kiyah Duffey & Lisa Sutherland. (2013) Adult Cranberry Beverage Consumers Have Healthier Macronutrient Intakes and Measures of Body Composition Compared to Non-Consumers: National Health and Nutrition Examination Survey (NHANES) 2005–2008. Nutrients 5:12, pages 4938-4949.
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Jeffrey B. Blumberg, Terri A. Camesano, Aedin Cassidy, Penny Kris-Etherton, Amy Howell, Claudine Manach, Luisa M. Ostertag, Helmut Sies, Ann Skulas-Ray & Joseph A. Vita. (2013) Cranberries and Their Bioactive Constituents in Human Health. Advances in Nutrition 4:6, pages 618-632.
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P. Minodier, J. Bréaud & E. Bérard. (2012) Pyélonéphrites à E. coli : stratégies prophylactiques. Archives de Pédiatrie 19, pages S117-S123.
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Ruth G Jepson, Gabrielle Williams & Jonathan C Craig. (2012) Cranberries for preventing urinary tract infections. Cochrane Database of Systematic Reviews 2014:6.
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Richard Grady. (2012) Editorial Comment. Journal of Urology 188:4S, pages 1587-1587.
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Stefan Weichert, Horst Schroten & Rüdiger Adam. (2012) The Role of Prebiotics and Probiotics in Prevention and Treatment of Childhood Infectious Diseases. Pediatric Infectious Disease Journal 31:8, pages 859-862.
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Hatice Mutlu & Zelal Ekinci. (2012) Urinary Tract Infection Prophylaxis in Children with Neurogenic Bladder with Cranberry Capsules: Randomized Controlled Trial. ISRN Pediatrics 2012, pages 1-4.
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Marcelo Hisano, Homero Bruschini, Antonio Carlos Nicodemo & Miguel Srougi. (2012) Cranberries and lower urinary tract infection prevention. Clinics 67:6, pages 661-667.
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Ahizechukwu C Eke, Sally N Akarolo-Anthony & Adaeze P Enumah. (2012) Cranberries for treating asymptomatic bacteriuria during pregnancy. Cochrane Database of Systematic Reviews.
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C.C. Cowan, C. Hutchison, T. Cole, S.J.E. Barry, J. Paul, N.S. Reed & J.M. Russell. (2012) A Randomised Double-blind Placebo-controlled Trial to Determine the Effect of Cranberry Juice on Decreasing the Incidence of Urinary Symptoms and Urinary Tract Infections in Patients Undergoing Radiotherapy for Cancer of the Bladder or Cervix. Clinical Oncology 24:2, pages e31-e38.
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Stephen Shei-Dei Yang, I-Ni Chiang, Chia-Da Lin & Shang-Jen Chang. (2011) Advances in non-surgical treatments for urinary tract infections in children. World Journal of Urology 30:1, pages 69-75.
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Ihsan Iswaldi, Ana María Gómez-Caravaca, David Arráez-Román, José Uberos, Marita Lardón, Antonio Segura-Carretero & Alberto Fernández-Gutiérrez. (2012) Characterization by high-performance liquid chromatography with diode-array detection coupled to time-of-flight mass spectrometry of the phenolic fraction in a cranberry syrup used to prevent urinary tract diseases, together with a study of its antibacterial activity. Journal of Pharmaceutical and Biomedical Analysis 58, pages 34-41.
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Richard W. Grady. 2012. Essential Urology. Essential Urology 15 26 .
Peter C. Wootton-Beard & Lisa Ryan. (2011) Improving public health?: The role of antioxidant-rich fruit and vegetable beverages. Food Research International 44:10, pages 3135-3148.
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Catherine Neto & Joe Vinson. 2011. Herbal Medicine. Herbal Medicine 107 130 .
C. Barbosa-Cesnik, M. B. Brown, M. Buxton, L. Zhang, J. DeBusscher & B. Foxman. (2011) Cranberry Juice Fails to Prevent Recurrent Urinary Tract Infection: Results From a Randomized Placebo-Controlled Trial. Clinical Infectious Diseases 52:1, pages 23-30.
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D.E. Coplen. (2010) Cranberry juice for the prevention of recurrent urinary tract infections: A randomized controlled trial in children. Yearbook of Urology 2010, pages 225-226.
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