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Xenobiotica

the fate of foreign compounds in biological systems

Volume 40, 2010 - Issue 7

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General Xenobiochemistry

In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity

K.H. TiongSchool of Pharmacy and Health Sciences, International Medical University 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, Malaysia

B.C. YiapSchool of Pharmacy and Health Sciences, International Medical University 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, Malaysia

E.L. TanSchool of Pharmacy and Health Sciences, International Medical University 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, Malaysia

R. IsmailPharmacogenetics Research Group, Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia

C.E. OngSchool of Medicine and Health Sciences, Monash University Sunway Campus, Jalan Lagoon Selatan, Bandar Sunway, Selangor, MalaysiaCorrespondence[email protected]

Pages 458-466 | Received 11 Jan 2010, Accepted 17 Mar 2010, Published online: 19 Apr 2010

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https://doi.org/10.3109/00498251003786749

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Sanmuga Priya Ekambaram, Senthamil Selvan Perumal & Sivasakthi Paramasivam. 2023. Handbook of Dietary Flavonoids. Handbook of Dietary Flavonoids 1 59 .

Mirza Bojić, Martin Kondža, Hrvoje Rimac, Goran Benković & Željan Maleš. (2019) The Effect of Flavonoid Aglycones on the CYP1A2, CYP2A6, CYP2C8 and CYP2D6 Enzymes Activity. Molecules 24:17, pages 3174.
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Elias Begas, Maria Bounitsi, Thomas Kilindris, Evangelos Kouvaras, Konstantinos Makaritsis, Demetrios Kouretas & Eftihia K. Asprodini. (2019) Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food and Chemical Toxicology 130, pages 32-43.
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Xiaoyi Qi, Tongyi Dou, Zhongqiong Wang, Jianming Wu, Ling Yang, Su Zeng, Mingming Deng, Muhan Lü & Sicheng Liang. (2019) Inhibition of human cytochrome P450 2A6 by 7-hydroxycoumarin analogues: Analysis of the structure-activity relationship and isoform selectivity. European Journal of Pharmaceutical Sciences 136, pages 104944.
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Elias Begas, Thomas Kilindris, Evangelos Kouvaras, Agoritsa Tsioutsioumi, Demetrios Kouretas & Eftihia K. Asprodini. (2018) Dietary effects of Sideritis scardica “mountain tea” on human in vivo activities of xenobiotic metabolizing enzymes in healthy subjects. Food and Chemical Toxicology 122, pages 38-48.
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Elias Begas, Athanasia Tsioutsiouliti, Evangelos Kouvaras, Serkos A. Haroutounian, Konstantinos M. Kasiotis, Dimitrios Kouretas & Eftihia Asprodini. (2017) Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers. Food and Chemical Toxicology 100, pages 80-89.
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Robert Domitrović & Iva Potočnjak. (2015) A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives. Archives of Toxicology 90:1, pages 39-79.
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F. Peter Guengerich. 2015. Cytochrome P450. Cytochrome P450 523 785 .

Haydar Çelik, Müberra Koşar & Emel Arinç. (2013) In vitro effects of myricetin, morin, apigenin, (+)-taxifolin, (+)-catechin, (−)-epicatechin, naringenin and naringin on cytochrome b5 reduction by purified NADH-cytochrome b5 reductase. Toxicology 308, pages 34-40.
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Wenjing Zhang, Bo Tang, Qilai Huang & Zichun Hua. (2012) Galangin inhibits tumor growth and metastasis of B16F10 melanoma. Journal of Cellular Biochemistry 114:1, pages 152-161.
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Guanyu Wang, Jiawei Zhang, Luying Liu, Sherven Sharma & Qinghua Dong. (2012) Quercetin Potentiates Doxorubicin Mediated Antitumor Effects against Liver Cancer through p53/Bcl-xl. PLoS ONE 7:12, pages e51764.
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Alexander V. LyubimovBill Gurley, Kim E. Fifer & Zöe Gardner. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 79 .

Chia Yong Pang, Joon Wah Mak, Rusli Ismail & Chin Eng Ong. (2012) In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8). Naunyn-Schmiedeberg's Archives of Pharmacology 385:5, pages 495-502.
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D.K. Patel, K. Patel, M. Gadewar & V. Tahilyani. (2012) Pharmacological and bioanalytical aspects of galangin-a concise report. Asian Pacific Journal of Tropical Biomedicine 2:1, pages S449-S455.
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G Bobe, G Murphy, P S Albert, L B Sansbury, E Lanza, A Schatzkin, N H Colburn & A J Cross. (2010) Serum cytokine concentrations, flavonol intake and colorectal adenoma recurrence in the Polyp Prevention Trial. British Journal of Cancer 103:9, pages 1453-1461.
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In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity

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In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity

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