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Jose Serrano, Mark A. Tapper, Richard C. Kolanczyk, Barbara R. Sheedy, Tylor Lahren, Dean E. Hammermeister, Jeffrey S. Denny, Michael W. Hornung, Alena Kubátová, Patricia A. Kosian, Jessica Voelker & Patricia K. Schmieder. (2020) Metabolism of cyclic phenones in rainbow trout in vitro assays. Xenobiotica 50:2, pages 115-131.
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Rodrigo F. Alves, Eduardo Rocha & Tânia V. Madureira. (2022) Fish hepatocyte spheroids – A powerful (though underexplored) alternative in vitro model to study hepatotoxicity. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 262, pages 109470.
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Inês L. Pereira, Célia Lopes, Eduardo Rocha & Tânia V. Madureira. (2022) Establishing brown trout primary hepatocyte spheroids as a new alternative experimental model—Testing the effects of 5α-dihydrotestosterone on lipid pathways. Aquatic Toxicology 253, pages 106331.
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Maurice Tust, Maxie Kohler, Andreas Lagojda & Marc Lamshoeft. (2021) Comparison of the in vitro assays to investigate the hepatic metabolism of seven pesticides in Cyprinus carpio and Oncorhynchus mykiss. Chemosphere 277, pages 130254.
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Toshiyuki Katagi. (2020) <i>In vitro</i> metabolism of pesticides and industrial chemicals in fish. Journal of Pesticide Science 45:1, pages 1-15.
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Tobias Lammel, Georgia Tsoukatou, Johanna Jellinek & Joachim Sturve. (2019) Development of three-dimensional (3D) spheroid cultures of the continuous rainbow trout liver cell line RTL-W1. Ecotoxicology and Environmental Safety 167, pages 250-258.
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Jennifer J. Trowell, Frank A. P. C. Gobas, Margo M. Moore & Christopher J. Kennedy. (2018) Estimating the Bioconcentration Factors of Hydrophobic Organic Compounds from Biotransformation Rates Using Rainbow Trout Hepatocytes. Archives of Environmental Contamination and Toxicology 75:2, pages 295-305.
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Laura M. Langan, Stewart F. Owen & Awadhesh N. Jha. (2018)
Establishment and long-term maintenance of primary intestinal epithelial cells cultured from the rainbow trout,
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Julita Stadnicka-Michalak, Frederik T. Weiss, Melanie Fischer, Katrin Tanneberger & Kristin Schirmer. (2018)
Biotransformation of Benzo[
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Kellie A. Fay, Patrick N. Fitzsimmons, Alex D. Hoffman & John W. Nichols. (2017) Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. Environmental Toxicology and Chemistry 36:2, pages 463-471.
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Matthew G. Baron, Kate S. Mintram, Stewart F. Owen, Malcolm J. Hetheridge, A. John Moody, Wendy M. Purcell, Simon K. Jackson & Awadhesh N. Jha. (2017) Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance. PLOS ONE 12:1, pages e0168837.
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Adam Lillicrap, Tim Springer & Charles R. Tyler. (2016) A tiered assessment strategy for more effective evaluation of bioaccumulation of chemicals in fish. Regulatory Toxicology and Pharmacology 75, pages 20-26.
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Lucy C. Stott, Sabine Schnell, Christer Hogstrand, Stewart F. Owen & Nic R. Bury. (2015) A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: Evidence for passive and facilitated transport. Aquatic Toxicology 159, pages 127-137.
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Chibuzor Uchea, Stewart F. Owen & J. Kevin Chipman. (2015) Functional xenobiotic metabolism and efflux transporters in trout hepatocyte spheroid cultures. Toxicology Research 4:2, pages 494-507.
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Heike Laue, Hans Gfeller, Karen J. Jenner, John W. Nichols, Susanne Kern & Andreas Natsch. (2014)
Predicting the Bioconcentration of Fragrance Ingredients by Rainbow Trout Using Measured Rates of
in Vitro
Intrinsic Clearance
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Yung-Shan Lee, Danny H.Y. Lee, Maximilien Delafoulhouze, S. Victoria Otton, Margo M. Moore, Chris J. Kennedy & Frank A.P.C. Gobas. (2014) In vitro biotransformation rates in fish liver S9: Effect of dosing techniques. Environmental Toxicology and Chemistry 33:8, pages 1885-1893.
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Mariann Rand-Weaver, Luigi Margiotta-Casaluci, Alpa Patel, Grace H. Panter, Stewart F. Owen & John P. Sumpter. (2013) The Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals. Environmental Science & Technology 47:20, pages 11384-11395.
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