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Risto O. Juvonen, Olli Pentikäinen, Juhani Huuskonen, Juri Timonen, Olli Kärkkäinen, Aki Heikkinen, Muluneh Fashe & Hannu Raunio. (2020) In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species. Xenobiotica 50:8, pages 885-893.
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Markus Koponen, Jaana Rysä, Anna-Kaisa Ruotsalainen, Olli Kärkkäinen & Risto O. Juvonen. (2023) Western Diet Decreases Hepatic Drug Metabolism in Male LDLr−/−ApoB100/100 Mice. Journal of Nutrition and Metabolism 2023, pages 1-12.
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Zhenhao Tian, Jiayue Wang, Yidan Gao, Xiaokui Huo, Zhenlong Yu, Yan Wang, Chao Wang, Lei Feng, Jingnan Cui & Xiangge Tian. (2022) “Domain Directional Optimization” strategy for the development of UGT1A1-activated fluorescent probe and the application in living systems. Sensors and Actuators B: Chemical 369, pages 132342.
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Qiang Jin, JingJing Wu, Yue Wu, Hongxin Li, Moshe Finel, Dandan Wang & Guangbo Ge. (2022) Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives. Acta Pharmaceutica Sinica B 12:3, pages 1068-1099.
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Hannu Raunio, Olli Pentikäinen & Risto O. Juvonen. (2020) Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro. International Journal of Molecular Sciences 21:13, pages 4708.
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Monika Pawłowska, Anna Kwaśniewska, Zofia Mazerska & Ewa Augustin. (2020) Enhanced Activity of P4503A4 and UGT1A10 Induced by Acridinone Derivatives C-1305 and C-1311 in MCF-7 and HCT116 Cancer Cells: Consequences for the Drugs’ Cytotoxicity, Metabolism and Cellular Response. International Journal of Molecular Sciences 21:11, pages 3954.
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Risto O. Juvonen, Aki T. Heikkinen, Olli Kärkkäinen, Rabia Jehangir, Juhani Huuskonen, Johanna Troberg, Hannu Raunio, Olli T. Pentikäinen & Moshe Finel. (2020) In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs. European Journal of Pharmaceutical Sciences 141, pages 105118.
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Ya-Yu Yang & Tung-Hu Tsai. (2019) Enterohepatic Circulation and Pharmacokinetics of Genistin and Genistein in Rats. ACS Omega 4:19, pages 18428-18433.
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Lei Feng, Jing Ning, Xiangge Tian, Chao Wang, Liyuan Zhang, Xiaochi Ma & Tony D. James. (2019) Fluorescent probes for bioactive detection and imaging of phase II metabolic enzymes. Coordination Chemistry Reviews 399, pages 213026.
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Xia Lv, Jian-Bin Zhang, Jie Hou, Tong-Yi Dou, Guang-Bo Ge, Wen-Zhong Hu & Ling Yang. (2019) Chemical Probes for Human UDP-Glucuronosyltransferases: A Comprehensive Review. Biotechnology Journal 14:1, pages 1800002.
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Risto O. Juvonen, Sanna Rauhamäki, Sami Kortet, Sanna Niinivehmas, Johanna Troberg, Aleksanteri Petsalo, Juhani Huuskonen, Hannu Raunio, Moshe Finel & Olli T. Pentikäinen. (2018) Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10. Molecular Pharmaceutics 15:3, pages 923-933.
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Thomas ZielinskiMelvin ReichmanPreston S. DonoverRobert G. Lowery. (2016) Development and Validation of a Universal High-Throughput UDP-Glycosyltransferase Assay with a Time-Resolved FRET Signal. ASSAY and Drug Development Technologies 14:4, pages 240-251.
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Aki T. Heikkinen, Arno Friedlein, Mariette Matondo, Oliver J. D. Hatley, Aleksanteri Petsalo, Risto Juvonen, Aleksandra Galetin, Amin Rostami-Hodjegan, Ruedi Aebersold, Jens Lamerz, Tom Dunkley, Paul Cutler & Neil Parrott. (2014) Quantitative ADME Proteomics – CYP and UGT Enzymes in the Beagle Dog Liver and Intestine. Pharmaceutical Research 32:1, pages 74-90.
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Erik Sjögren, Bertil Abrahamsson, Patrick Augustijns, Dieter Becker, Michael B. Bolger, Marcus Brewster, Joachim Brouwers, Talia Flanagan, Matthew Harwood, Christian Heinen, René Holm, Hans-Paul Juretschke, Marlies Kubbinga, Anders Lindahl, Viera Lukacova, Uwe Münster, Sibylle Neuhoff, Mai Anh Nguyen, Achiel van Peer, Christos Reppas, Amin Rostami Hodjegan, Christer Tannergren, Werner Weitschies, Clive Wilson, Patricia Zane, Hans Lennernäs & Peter Langguth. (2014) In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects. European Journal of Pharmaceutical Sciences 57, pages 99-151.
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