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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 8
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Research Article

Identification of saturated and unsaturated fatty acids released during microsomal incubations

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Pages 687-695 | Received 15 Nov 2013, Accepted 13 Jan 2014, Published online: 06 Feb 2014

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Gurinder Walia, Alexander D. Smith, Zoe Riches, Abby C. Collier & Michael W. H. Coughtrie. (2018) The effects of UDP-sugars, UDP and Mg2+on uridine diphosphate glucuronosyltransferase activity in human liver microsomes. Xenobiotica 48:9, pages 882-890.
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John O. Miners, Andrew Rowland, Jonathan J. Novak, Kimberly Lapham & Theunis C. Goosen. (2021) Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping. Pharmacology & Therapeutics 218, pages 107689.
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Priyanka R. Kulkarni, Amir S. Youssef & Aneesh A. Argikar. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 369 417 .
Jin Zhou, Upendra A. Argikar & John O. Miners. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 301 338 .
Steffen Landerer, Sandra Kalthoff, Stefan Paulusch & Christian P. Strassburg. (2020) A Gilbert syndrome-associated haplotype protects against fatty liver disease in humanized transgenic mice. Scientific Reports 10:1.
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Rasa Santockyte, Hamza Kandoussi, Weiqi Chen, Naiyu Zheng, Lata Venkatarangan, Jinping Gan, Hong Shen, Samuel J Bonacorsi, John Easter, Richard Burrell, Yan J Zhang & Jianing Zeng. (2018) LC–MS/MS bioanalysis of plasma 1, 14-tetradecanedioic acid and 1, 16-hexadecanedioic acid as candidate biomarkers for organic anion-transporting polypeptide mediated drug–drug interactions. Bioanalysis 10:18, pages 1473-1485.
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Raghava Choudary Palacharla, Venkatesham Uthukam, Arunkumar Manoharan, Ranjith Kumar Ponnamaneni, Nagasurya Prakash Padala, Rajesh Kumar Boggavarapu, Gopinadh Bhyrapuneni, Devender Reddy Ajjala & Ramakrishna Nirogi. (2017) Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro – in vivo extrapolation of hepatic clearance. European Journal of Pharmaceutical Sciences 101, pages 80-89.
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Upendra A. Argikar, Philip M. Potter, J. Matthew Hutzler & Punit H. Marathe. (2016) Challenges and Opportunities with Non-CYP Enzymes Aldehyde Oxidase, Carboxylesterase, and UDP-Glucuronosyltransferase: Focus on Reaction Phenotyping and Prediction of Human Clearance. The AAPS Journal 18:6, pages 1391-1405.
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