Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 2
414
Views
24
CrossRef citations to date
0
Altmetric
Animal pharmacokinetics and metabolism

Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus)

, , , , , , & show all
Pages 163-168 | Received 13 May 2015, Accepted 28 May 2015, Published online: 26 Jun 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Shogo Matsumoto, Shotaro Uehara, Hidetaka Kamimura, Hiroshi Ikeda, Satoshi Maeda, Machiko Hattori, Megumi Nishiwaki, Kazuhiko Kato & Hiroshi Yamazaki. (2021) Human total clearance values and volumes of distribution of typical human cytochrome P450 2C9/19 substrates predicted by single-species allometric scaling using pharmacokinetic data sets from common marmosets genotyped for P450 2C19. Xenobiotica 51:4, pages 479-493.
Read now
Takashi Kusama, Akiko Toda, Makiko Shimizu, Shotaro Uehara, Takashi Inoue, Yasuhiro Uno, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki. (2018) Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models. Xenobiotica 48:10, pages 1072-1077.
Read now
Akiko Toda, Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Takashi Kusama, Makiko Shimizu, Yasuhiro Uno, Masayuki Mogi, Erika Sasaki & Hiroshi Yamazaki. (2018) Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. Xenobiotica 48:7, pages 720-726.
Read now
Shotaro Uehara, Yukako Yuki, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2018) Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines. Xenobiotica 48:4, pages 342-347.
Read now
Shotaro Uehara, Yasuhiro Uno, Sakura Ishii, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Marmoset cytochrome P450 4A11, a novel arachidonic acid and lauric acid ω-hydroxylase expressed in liver and kidney tissues. Xenobiotica 47:7, pages 553-561.
Read now
Masahiro Utoh, Hiroshi Suemizu, Marina Mitsui, Mirai Kawano, Akiko Toda, Shotaro Uehara, Yasuhiro Uno, Makiko Shimizu, Erika Sasaki & Hiroshi Yamazaki. (2016) Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling. Xenobiotica 46:12, pages 1049-1055.
Read now
Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Eriko Okamoto, Erika Sasaki & Hiroshi Yamazaki. (2016) Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine. Xenobiotica 46:11, pages 977-985.
Read now
Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Takako Suzuki, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki. (2016) Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets. Xenobiotica 46:7, pages 573-578.
Read now

Articles from other publishers (15)

Kanako Muta, Junichi Hata, Naoki Kawaguchi, Yawara Haga, Daisuke Yoshimaru, Kei Hagiya, Takaaki Kaneko, Takako Miyabe-Nishiwaki, Yuji Komaki, Fumiko Seki, Hirotaka James Okano & Hideyuki Okano. (2023) Effect of sedatives or anesthetics on the measurement of resting brain function in common marmosets. Cerebral Cortex 33:9, pages 5148-5162.
Crossref
Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary 329 364 .
Jessica Ann Herrod, Janelle Arcey Avelino, Kayla Marie Schonvisky, Jessica Kay Lynch, Eric Kenneth Hutchinson & Jessica Marie Izzi. (2021) The use of midazolam as an appetite stimulant and anxiolytic in the common marmoset ( Callithrix jacchus ) . Journal of Medical Primatology 50:5, pages 249-258.
Crossref
Shotaro Uehara, Yasuhiro Uno & Hiroshi Yamazaki. (2020) The marmoset cytochrome P450 superfamily: Sequence/phylogenetic analyses, genomic structure, and catalytic function. Biochemical Pharmacology 171, pages 113721.
Crossref
Shotaro Uehara, Toru Oshio, Kazuyuki Nakanishi, Etsuko Tomioka, Miyu Suzuki, Takashi Inoue, Yasuhiro Uno, Erika Sasaki & Hiroshi Yamazaki. (2019) Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model. Current Drug Metabolism 20:2, pages 103-113.
Crossref
Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2018) Genetic polymorphisms of drug-metabolizing cytochrome P450 enzymes in cynomolgus and rhesus monkeys and common marmosets in preclinical studies for humans. Biochemical Pharmacology 153, pages 184-195.
Crossref
Kazuyuki Nakanishi, Shotaro Uehara, Takashi Kusama, Takashi Inoue, Kanami Shimura, Yusuke Kamiya, Norie Murayama, Makiko Shimizu, Yasuhiro Uno, Erika Sasaki & Hiroshi Yamazaki. (2018) In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants. Biochemical Pharmacology 152, pages 272-278.
Crossref
Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metabolism and Disposition 45:5, pages 457-467.
Crossref
Hiroshi Yamazaki. (2016) Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes. Chemical Research in Toxicology 30:1, pages 53-60.
Crossref
H. Yamazaki. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 45 50 .
Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. (2016) Utility of non-human primates in drug development: Comparison of non-human primate and human drug-metabolizing cytochrome P450 enzymes. Biochemical Pharmacology 121, pages 1-7.
Crossref
Shotaro Uehara, Mirai Kawano, Norie Murayama, Yasuhiro Uno, Masahiro Utoh, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2016) Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets. Biochemical Pharmacology 120, pages 56-62.
Crossref
S. Uehara, Y. Uno, T. Inoue, M. Kawano, M. Shimizu, A. Toda, M. Utoh, E. Sasaki & H. Yamazaki. (2016) Individual Differences in Metabolic Clearance of S-Warfarin Efficiently Mediated by Polymorphic Marmoset Cytochrome P450 2C19 in Livers. Drug Metabolism and Disposition 44:7, pages 911-915.
Crossref
S. Uehara, Y. Uno, Y. Yuki, T. Inoue, E. Sasaki & H. Yamazaki. (2016) A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine. Drug Metabolism and Disposition 44:6, pages 833-841.
Crossref
Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki. (2015) Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S -Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole . Drug Metabolism and Disposition 43:10, pages 1408-1416.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.