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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 12
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Review Article

Techniques for microfloral and associated metabolic studies in relation to the absorption and enterohepatic circulation of drugs

Pages 815-830 | Received 03 Nov 1981, Published online: 30 Sep 2009

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P. W. Slattum, A. E. Cato, G. M. Pollack & K. L. R. Brouwer. (1995) Age-dependent intestinal hydrolysis of valproate glucuronide in rat. Xenobiotica 25:3, pages 229-237.
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R. Perego, P. Beccaglia, M. Angelini, P. Villa & D. Cova. (1993) Pharmacokinetic studies of diosmin and diosmetin in perfused rat liver. Xenobiotica 23:12, pages 1345-1352.
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L. R. Kao & L. S. Birnbaum. (1986) Disposition of o‐benzyl‐p‐chlorophenol in male rats. Journal of Toxicology and Environmental Health 18:3, pages 441-458.
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Articles from other publishers (22)

Xue Liang & Garret A. FitzGerald. (2017) Timing the Microbes: The Circadian Rhythm of the Gut Microbiome. Journal of Biological Rhythms 32:6, pages 505-515.
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Ian D. Wilson & Jeremy K. Nicholson. (2017) Gut microbiome interactions with drug metabolism, efficacy, and toxicity. Translational Research 179, pages 204-222.
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Angeliki Balasopoulou, George P. Patrinos & Theodora Katsila. (2016) Pharmacometabolomics Informs Viromics toward Precision Medicine. Frontiers in Pharmacology 7.
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Shiyu Ma, Lan Shen, Meiwan Chen, Xiao Lin, Qiang Wang, Ruofei Du & Yi Feng. (2015) The study of metabonomics combined with diversity of intestinal flora in LDP intervention in kidney-yin deficiency hyperthyroid rats. RSC Advances 5:71, pages 57975-57983.
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Ian D. Wilson & Jeremy K. Nicholson. 2015. Metabonomics and Gut Microbiota in Nutrition and Disease. Metabonomics and Gut Microbiota in Nutrition and Disease 323 341 .
Chunyan Zhao, Runbin Sun, Bei Cao, Shenghua Gu, Jieyu Zhao, Linsheng Liu, Xinwen Wang, Weibin Zha, Xiaoyi Yu, Wenjing Xiao, Yong Mao, Chun Ge, Jiaqi Ju, Lixiang Aa, Fei Fei, Yi Ding, Jiye Aa & Guangji Wang. (2013) An in vitro metabolic system of gut flora and the metabolism of ginsenoside Rg3 and cholic acid. European Journal of Drug Metabolism and Pharmacokinetics 39:2, pages 129-137.
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Jeremy K. Nicholson, Elaine Holmes & Ian D. Wilson. (2005) Gut microorganisms, mammalian metabolism and personalized health care. Nature Reviews Microbiology 3:5, pages 431-438.
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AP Moghaddam, R. Abbas, JW Fisher & JC Lipscomb. (2016) The role of mouse intestinal microflora in the metabolism of trichloroethylene, an in vivo study. Human & Experimental Toxicology 16:11, pages 629-635.
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Janice Hunter & Barry H. Hirst. (1997) Intestinal secretion of drugs. The role of P-glycoprotein and related drug efflux systems in limiting oral drug absorption. Advanced Drug Delivery Reviews 25:2-3, pages 129-157.
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Bruce J. Aungst. (1993) Novel Formulation Strategies for Improving Oral Bioavailability of Drugs with Poor Membrane Permeation or Presystemic Metabolism. Journal of Pharmaceutical Sciences 82:10, pages 979-987.
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Michael J. Skibic, K.Wayne Taylor, John L. Occolowitz, Monte W. Collins, John W. Paschal, Leslie J. Lorenz, Larry A. Spangle, Douglas E. Dorman & Steven W. Baertschi. (1993) Aqueous Acidic Degradation of the Carbacephalosporin Loracarbef. Journal of Pharmaceutical Sciences 82:10, pages 1010-1017.
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M.Abu Shamat. (1993) The role of the gastrointestinal microflora in the metabolism of drugs. International Journal of Pharmaceutics 97:1-3, pages 1-13.
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Satoshi Takeno & Takeshi Sakai. (2005) Involvement of the intestinal microflora in nitrazepam‐induced teratogenicity in rats and its relationship to nitroreduction. Teratology 44:2, pages 209-214.
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Sen Kau, Christopher Yochim, My Linh Do, Krystyna Leszczynska, Chester Andruskiewicz, Jaek Schwartz, Jack Li & Burton Howe. (1991) ICI 181,037: A Novel Eukalemic Diuretic with Antiarrhythmic Activity. Japanese Journal of Pharmacology 57:3, pages 263-277.
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M.P. Hazenberg, W.W. Herder & T.J. Visser. (1988) Hydrolysis of iodothyronine conjugates by intestinal bacteria. FEMS Microbiology Letters 54:1, pages 9-16.
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M.E. COATES, B.S. DRASAR, A.K. MALLETT & I.R. ROWLAND. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 1 21 .
C.E. Carnovale, R.A. Marinelli & E.A.Rodriguez Garay. (1987) Toxic effect of streptozotocin on the biliary secretion of nicotinamide-treated rats. Toxicology Letters 36:3, pages 259-265.
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J. van Eldere, G. Parmentier, J. Robben & H. Eyssen. (1987) Influence of an estrone-desulfating intestinal flora on the enterohepatic circulation of estrone-sulfate in rats. Journal of Steroid Biochemistry 26:2, pages 235-239.
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Cristina E. Carnovale, Raúl A. Marinelli & E.A.Rodrlguez Garay. (1986) Bile flow decrease and altered bile composition in streptozotocin-treated rats. Biochemical Pharmacology 35:15, pages 2625-2628.
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Michele A. Medinsky, Heather Shelton, James A. Shelton & Roger O. McClellan. (1985) Biliary excretion and enterohepatic circulation of 1-nitropyrene metabolites in fischer-344 rats. Biochemical Pharmacology 34:13, pages 2325-2330.
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Peter C. Ruenitz & Jerome R. Bagley. (1983) Formation of benzophenone and α,α-diarylacetophenone metabolites of the antiestrogen nitromiphene (CI628) in the presence of rat cecal contents. Life Sciences 33:11, pages 1051-1056.
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Si Mui Sim, Suzanne Huijghebaert, D.J. Back & H.J. Eyssen. (1983) Gastrointestinal absorption of estrone sulfate in germfree and conventional rats. Journal of Steroid Biochemistry 18:4, pages 499-503.
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