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Xenobiotica
the fate of foreign compounds in biological systems
Volume 16, 1986 - Issue 6
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Original Article

Enzyme activities of the hindgut microflora of laboratory animals and man

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Pages 519-523 | Received 06 May 1985, Published online: 30 Sep 2009

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Min Zhao, Jun Xu, Dawei Qian, Jianming Guo, Shu Jiang, Er-xin Shang, Jin-ao Duan & Leyue Du. (2014) Characterization of in Vitro Metabolism of Loganin by Human Intestinal Microflora Using Ultra-High Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry. Analytical Letters 47:9, pages 1500-1512.
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Myra L. Weiner. (2014) Food additive carrageenan: Part II: A critical review of carrageenan in vivo safety studies. Critical Reviews in Toxicology 44:3, pages 244-269.
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Hee Ji Lee, Hu Zhang, David A. Orlovich & J. Paul Fawcett. (2012) The influence of probiotic treatment on sulfasalazine metabolism in rat. Xenobiotica 42:8, pages 791-797.
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Ines A Pieper & Martin Bertau. (2010) Predictive tools for the evaluation of microbial effects on drugs during gastrointestinal passage. Expert Opinion on Drug Metabolism & Toxicology 6:6, pages 747-760.
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Rolf Gebhardt, Jan G. Hengstler, Dieter Müller, Reinhild Glöckner, Peter Buenning, Britta Laube, Eva Schmelzer, Martina Ullrich, Dietmar Utesch, Nicola Hewitt, Michael Ringel, Beate Reder Hilz, Augustinus Bader, Angelika Langsch, Thomas Koose, Hans-Jörg Burger, Jochen Maas & Franz Oesch. (2003) New Hepatocyte In Vitro Systems for Drug Metabolism: Metabolic Capacity and Recommendations for Application in Basic Research and Drug Development, Standard Operation Procedures. Drug Metabolism Reviews 35:2-3, pages 145-213.
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King‐Thom Chung. (2000) Mutagenicity and carcinogenicity of aromatic amines metabolically produced from Azo Dyes. Journal of Environmental Science and Health, Part C 18:1, pages 51-74.
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A. J. McBain & G. T. Macfarlane. (1997) Investigations of Bifidobacterial Ecology and Oligosaccharide Metabolism in a Three-Stage Compound Continuous Culture System. Scandinavian Journal of Gastroenterology 32:sup222, pages 32-40.
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M. Tamura, K. Hirayama & K. Itoh. (1996) Comparison of Colonic Bacterial Enzymes in Gnotobiotic Mice Monoassociated with Different Intestinal Bacteria. Microbial Ecology in Health and Disease 9:6, pages 287-294.
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ElainaM. Kenyon & EdwardJ. Calabrese. (1994) Comparison of three methods of expressing ß‐glucuronidase activity in intestinal contents. Journal of Environmental Science and Health . Part A: Environmental Science and Engineering and Toxicology 29:7, pages 1305-1315.
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Walter Majak. (1992) Mammalian Metabolism of Toxic Glycosides from Plants. Journal of Toxicology: Toxin Reviews 11:1, pages 1-40.
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King-Thorn Chung, S. Edward Stevens & Carl E. Cerniglia. (1992) The Reduction of Azo Dyes by the Intestinal Microflora. Critical Reviews in Microbiology 18:3, pages 175-190.
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Robert W. Chadwick, S. Elizabeth George & Larry D. Claxton. (1992) Role of the Gastrointestinal Mucosa and Microflora in the Bioactivation of Dietary and Environmental Mutagens or Carcinogens. Drug Metabolism Reviews 24:4, pages 425-492.
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CorinneJ. Rumney & IanR. Rowland. (1992) In vivo and in vitro models of the human colonic flora. Critical Reviews in Food Science and Nutrition 31:4, pages 299-331.
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KathleenW. Nolan, EdwardJ. Calabrese & Elaina Kenyon. (1990) Effect of ascorbic acid supplementation on beta‐glucuronidase activity in urine, intestinal, and cecal contents of rats. Journal of Environmental Science and Health . Part A: Environmental Science and Engineering and Toxicology 25:3, pages 299-316.
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I. R. Rowland. (1988) Factors Affecting Metabolic Activity of the Intestinal Microflora. Drug Metabolism Reviews 19:3-4, pages 243-261.
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Jacinta Walsh, Loreto Olavarria-Ramirez, Gilliard Lach, Marcus Boehme, Timothy G. Dinan, John F. Cryan, Brendan T. Griffin, Niall P. Hyland & Gerard Clarke. (2020) Impact of host and environmental factors on β-glucuronidase enzymatic activity: implications for gastrointestinal serotonin. American Journal of Physiology-Gastrointestinal and Liver Physiology 318:4, pages G816-G826.
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Xue Liang & Garret A. FitzGerald. (2017) Timing the Microbes: The Circadian Rhythm of the Gut Microbiome. Journal of Biological Rhythms 32:6, pages 505-515.
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Keumhan Noh, You Ra Kang, Mahesh Raj Nepal, Rajina Shakya, Mi Jeong Kang, Wonku Kang, Sangkyu Lee, Hye Gwang Jeong & Tae Cheon Jeong. (2017) Impact of gut microbiota on drug metabolism: an update for safe and effective use of drugs. Archives of Pharmacal Research 40:12, pages 1345-1355.
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Jin-hua Tao, Jin-ao Duan, Yi-yun Qian, Da-wei Qian & Jian-ming Guo. (2016) Investigation of the interactions between Chrysanthemum morifolium flowers extract and intestinal bacteria from human and rat . Biomedical Chromatography 30:11, pages 1807-1819.
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Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie & Yongmei Li. (2015) Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies. Drug Metabolism and Disposition 43:10, pages 1612-1618.
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Shayne Gad, Charlie Clifford & Dawn Goodman. 2015. Animal Models in Toxicology, Third Edition. Animal Models in Toxicology, Third Edition 21 151 .
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Min Zhao, Leyue Du, Jinhua Tao, Dawei Qian, Jianming Guo, Shu Jiang, Er-xin Shang, Jin-ao Duan & Chen Wu. (2015) Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry for rapid analysis of the metabolites of morroniside produced by human intestinal bacteria. Journal of Chromatography B 976-977, pages 61-67.
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Chaowalit Yuajit, Chatchai Muanprasat, Anna-Rachel Gallagher, Sorin V. Fedeles, Suticha Kittayaruksakul, Sureeporn Homvisasevongsa, Stefan Somlo & Varanuj Chatsudthipong. (2014) Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease. Biochemical Pharmacology 88:3, pages 412-421.
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Suzanne M. Snedeker & Anthony G. Hay. (2012) Do Interactions Between Gut Ecology and Environmental Chemicals Contribute to Obesity and Diabetes?. Environmental Health Perspectives 120:3, pages 332-339.
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E.M. Kenyon & M.F. Hughes. 2010. Comprehensive Toxicology. Comprehensive Toxicology 61 74 .
Tiago Sousa, Ronnie Paterson, Vanessa Moore, Anders Carlsson, Bertil Abrahamsson & Abdul W. Basit. (2008) The gastrointestinal microbiota as a site for the biotransformation of drugs. International Journal of Pharmaceutics 363:1-2, pages 1-25.
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Hirokazu Sakamoto, Hiroshi Yokota, Ryoko Kibe, Yoshikatu Sayama & Akira Yuasa. (2002) Excretion of bisphenol A-glucuronide into the small intestine and deconjugation in the cecum of the rat. Biochimica et Biophysica Acta (BBA) - General Subjects 1573:2, pages 171-176.
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David A. Flockhart & Jessica R. Oesterheld. (2000) Cytochrome P450-Mediated Drug Interactions. Child and Adolescent Psychiatric Clinics of North America 9:1, pages 43-76.
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Kazuhiro HIRAYAMA. (1999) Ex-Germfree Mice Harboring Intestinal Microbiota Derived from Other Animal Species as an Experimental Model for Ecology and Metabolism of Intestinal Bacteria.. Experimental Animals 48:4, pages 219-227.
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