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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 2
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Original Article

The metabolism of some pentachlorodibenzofurans in the rat

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Pages 209-216 | Received 24 Feb 1986, Published online: 30 Sep 2009

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Martin Van den Berg, Joost De Jongh, Hermann Poiger & James R. Olson. (1994) The Toxicokinetics and Metabolism of Polychlorinated Dibenzo-p-Dioxins (PCDDs) and Dibenzofurans (PCDFs) and Their Relevance for Toxicity. Critical Reviews in Toxicology 24:1, pages 1-74.
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J. de Jongh, H. R. Buser & H. Poiger. (1993) The metabolism of 2,3,7,8-tetrabromodibenzodioxin in the rat. Xenobiotica 23:1, pages 19-26.
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H. Kamimura, N. Koga, K. Oguri, H. Yoshimura, Y. Honda & M. Nakano. (1988) Enhanced faecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats by a long-term treatment with activated charcoal beads. Xenobiotica 18:5, pages 585-592.
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Articles from other publishers (24)

Yan Bao, Lei Zhang, Xin Liu, Lei Shi, Jingguang Li, Guimin Meng, Yunfeng Zhao & Yongning Wu. (2020) Dioxin-like compounds in paired maternal serum and breast milk under long sampling intervals. Ecotoxicology and Environmental Safety 194, pages 110339.
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Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Peter Fürst, Helen Håkansson, Thorhallur Halldorsson, Anne‐Katrine Lundebye, Raimo Pohjanvirta, Lars Rylander, Andrew Smith, Henk van Loveren, Ine Waalkens‐Berendsen, Marco Zeilmaker, Marco Binaglia, José Ángel Gómez Ruiz, Zsuzsanna Horváth, Eugen Christoph, Laura Ciccolallo, Luisa Ramos Bordajandi, Hans Steinkellner & Laurentius (Ron) Hoogenboom. (2018) Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food. EFSA Journal 16:11.
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F. Girolami, V. Spalenza, A. Benedetto, L. Manzini, P. Badino, M.C. Abete & C. Nebbia. (2016) Comparative liver accumulation of dioxin-like compounds in sheep and cattle: Possible role of AhR-mediated xenobiotic metabolizing enzymes. Science of The Total Environment 571, pages 1222-1229.
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Chia-Yang Chen, Jonathan T. Hamm, J.Ronald Hass & Linda S. Birnbaum. (2001) Disposition of Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and non-ortho Polychlorinated Biphenyls in Pregnant Long Evans Rats and the Transfer to Offspring. Toxicology and Applied Pharmacology 173:2, pages 65-88.
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A K D Liem, C E J Cuijpers & M J Zeilmaker. 2001. Persistent Organic Pollutants. Persistent Organic Pollutants 105 144 .
Elena Fattore, Christina Trossvik & Helen Håkansson. (2000) Relative Potency Values Derived from Hepatic Vitamin A Reduction in Male and Female Sprague–Dawley Rats Following Subchronic Dietary Exposure to Individual Polychlorinated Dibenzo-p-dioxin and Dibenzofuran Congeners and a Mixture Thereof. Toxicology and Applied Pharmacology 165:3, pages 184-194.
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Janet J. Diliberto, Deborah E. Burgin & Linda S. Birnbaum. (1999) Effects of CYP1A2 on Disposition of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-Pentachlorodibenzofuran, and 2,2′,4,4′,5,5′-Hexachlorobiphenyl in CYP1A2 Knockout and Parental (C57BL/6N and 129/Sv) Strains of Mice. Toxicology and Applied Pharmacology 159:1, pages 52-64.
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J.K. Huwe, V.J. Feil, G.L. Larsen & C. Wiener. (1998) Metabolism and disposition of 1,4,7,8-tetrachlorodibenzo p-dioxin in rats. Chemosphere 37:9-12, pages 1885-1893.
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Rolf-Michael Wittich. 1998. Biodegradation of Dioxins and Furans. Biodegradation of Dioxins and Furans 125 133 .
Marcellino J.C. Rozemeijer, Nick Green, Begoña Jiménez, Marco A. Adrichem, Kees Olie & Pim de Voogt. (1996) Integrating gel permeation chromatography clean-up in the analysis of metabolites of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans extracted from a microsomal assay A comparison of different mobile phases. Journal of Chromatography A 755:1, pages 57-66.
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H. Loonen, M. Tonkes, J.R. Parsons & H.A.J. Govers. (1994) Bioconcentration of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in guppies after aqueous exposure to a complex PCDD/PCDF mixture: relationship with molecular structure. Aquatic Toxicology 30:2, pages 153-169.
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Ulf G. Ahlborg, Abraham Brouwer, Marilyn A. Fingerhut, Joseph L. Jacobson, Sandra W. Jacobson, Sean W. Kennedy, Antonius A.F. Kettrup, Jan H. Koeman, Hermann Poiger, Christoffer Rappe, Stephen H. Safe, Richard F. Seegal, Jouko Tuomisto & Martin van den Berg. (1992) Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. European Journal of Pharmacology: Environmental Toxicology and Pharmacology 228:4, pages 179-199.
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Seishiro Hirano, Chiharu Tohyama, Fumiyuki Mitsumori, Hiroyasu Ito & Kazuo T. Suzuki. (1991) Identification of metabolites of 2-chlorodibenzofuran in the rat. Archives of Environmental Contamination and Toxicology 20:1, pages 67-72.
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H. Kuroki, K. Haraguchi & Y. Masuda. (1990) Metabolism of polychlorinated dibenzofurans (PCDFs) in rats. Chemosphere 20:7-9, pages 1059-1064.
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M. van den Berg, J. van Wijnen, H. Wever & W. Seinen. (1989) Selective retention of toxic polychlorinated dibenzo-p-dioxins and dibenzofurans in the liver of the rat after intravenous administration of a mixture. Toxicology 55:1-2, pages 173-182.
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Peter Kovacic, James R. Ames, Douglas L. Rector, Mikolaj Jawdosiuk & Michael D. Ryan. (1989) Reduction potentials of anthelmintic drugs: Possible relationship to activity. Free Radical Biology and Medicine 6:2, pages 131-139.
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H. Kuroki, R. Hattori, K. Haraguchi & Y. Masuda. (1989) Metabolism of 2,8-dichlorodibenzofuran in rats. Chemosphere 19:1-6, pages 803-808.
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Martin Van den Berg, Carolien Bouwman & Willem Seinen. (1989) Hepatic retention of PCDDs and PCDFs in C57BI/6 and DBA/2 Mice. Chemosphere 19:1-6, pages 795-802.
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Martin van den Berg & Hermann Poiger. (1989) Selective retention of PCDDs and PCDFs in mammals: A multiple cause problem. Chemosphere 18:1-6, pages 677-680.
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Martin Van den Berg, Joost de Jongh, Petra Eckhart & Frans W.M. Van der Wielen. (1989) The elimination and absence of pharmacokinetic interaction of some polychlorinated dibenzofurans (PCDFs) in the liver of the rat. Chemosphere 18:1-6, pages 665-675.
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H. Poiger, N. Pluess & H.R. Buser. (1989) The metabolism of selected PCDFs in the rat. Chemosphere 18:1-6, pages 259-264.
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David W. Brewster & Linda S. Birnbaum. (1988) Disposition of 1,2,3,7,8-pentachlorodibenzofuran in the rat. Toxicology and Applied Pharmacology 95:3, pages 490-498.
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N. Plüss, H. Poiger, C. Hohbach, M. Suter & C. Schlatter. (1988) Subchronic toxicity of 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) in rats. Chemosphere 17:6, pages 1099-1110.
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N. Pluess, H. Poiger, C. Hohbach & C. Schlatter. (1988) Subchronic toxicity of some chlorinated dibenzofurans (PCDFs) and a mixture of PCDFs and chlorinated dibenzodioxins (PCDDs) in rats. Chemosphere 17:5, pages 973-984.
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