Advanced search
Publication Cover
The American Journal of Drug and Alcohol Abuse
Encompassing All Addictive Disorders
Volume 37, 2011 - Issue 1
Submit an article Journal homepage
333
Views
30
CrossRef citations to date
0
Altmetric
Full Reviews

The association between naltrexone treatment and symptoms of depression in opioid-dependent patients

David J. Mysels Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA; Department of Outpatient Addictions Treatment, Cambridge Health Alliance, Somerville, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USACorrespondence[email protected]
, M.D., M.B.A.,
Wendy Y. Cheng Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
, M.P.H.,
Edward V. Nunes Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
, M.D. &
Maria A. Sullivan Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA; Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
, M.D., Ph.D.
Pages 22-26 | Published online: 30 Dec 2010

Citations (30)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Miranda G. Greiner, Matisyahu Shulman, Jennifer Scodes, Tse-Hwei Choo, Martina Pavlicova, Onumara Opara, Aimee N. C. Campbell, Patricia Novo, Marc Fishman, Joshua D. Lee, John Rotrosen & Edward V. Nunes. (2022) Patient Characteristics Associated with Opioid Abstinence after Participation in a Trial of Buprenorphine versus Injectable Naltrexone. Substance Use & Misuse 57:11, pages 1732-1742.
Read now
Christian Nwabueze,Hilary Elom,Sophia Liu,Suzy Mascaro Walter,Zhanxin Sha,Priscila Acevedo,Ying Liu,Brenda Bin Su,Chun Xu,Ubolrat Piamjariyakul,Kesheng Wang,. (2022) Gender differences in the associations of multiple psychiatric and chronic conditions with major depressive disorder among patients with opioid use disorder. Journal of Addictive Diseases 40:2, pages 168-178.
Read now
Evgeny Krupitsky, Edwin Zvartau, Elena Blokhina, Elena Verbitskaya, Valentina Wahlgren, Marina Tsoy-Podosenin, Natalia Bushara, Andrey Burakov, Dmitry Masalov, Tatyana Romanova, Arina Tyurina, Vladimir Palatkin, Tatyana Yaroslavtseva, Anna Pecoraro & George Woody. (2016) Anhedonia, depression, anxiety, and craving in opiate dependent patients stabilized on oral naltrexone or an extended release naltrexone implant. The American Journal of Drug and Alcohol Abuse 42:5, pages 614-620.
Read now
Paolo Mannelli, Kathleen S Peindl & Li-Tzy Wu. (2011) Pharmacological enhancement of naltrexone treatment for opioid dependence: a review. Substance Abuse and Rehabilitation 2, pages 113-123.
Read now

Articles from other publishers (26)

Noel Vest, Kevin Wenzel, Tse‐Hwei Choo, Martina Pavlicova, John Rotrosen, Edward Nunes, Joshua D. Lee & Marc Fishman. (2023) Trajectories of depression among patients in treatment for opioid use disorder: A growth mixture model secondary analysis of the XBOT trial. The American Journal on Addictions 32:3, pages 291-300.
Crossref
Hildegard A. Wulf, Caroline A. Browne, Carlos A. Zarate & Irwin Lucki. (2022) Mediation of the behavioral effects of ketamine and (2R,6R)-hydroxynorketamine in mice by kappa opioid receptors. Psychopharmacology 239:7, pages 2309-2316.
Crossref
Dilek Kaya-Akyüzlü, Selin Özkan-Kotiloğlu, Şafak Yalçın-Şahiner, Ece Ağtaş-Ertan & İnci Özgür-İlhan. (2022) Association of PDYN 68-bp VNTR polymorphism with sublingual buprenorphine/naloxone treatment and with opioid or alcohol use disorder: Effect on craving, depression, anxiety and age onset of first use. European Journal of Pharmacology 921, pages 174862.
Crossref
Insha Mehraj KakNeelofer Jan. (2022) NALTREXONE AS A TREATMENT FOR HEROIN DEPENDENCE AND ITS RELATIONSHIP WITH DEPRESSION. INDIAN JOURNAL OF APPLIED RESEARCH, pages 34-36.
Crossref
Kesheng Wang, Toni DiChiacchio, Wei Fang, Laura Lander, Judith Feinberg, Changchun Xie, Erin L. Winstanley & Ubolrat Piamjariyakul. (2022) Longitudinal study of impact of medication for opioid use disorder on Hamilton Depression Rating Scale. Journal of Affective Disorders 297, pages 148-155.
Crossref
Kara E. Rudolph, Iván Díaz, Nima S. Hejazi, Mark J. Laan, Sean X. Luo, Matisyahu Shulman, Aimee Campbell, John Rotrosen & Edward V. Nunes. (2021) Explaining differential effects of medication for opioid use disorder using a novel approach incorporating mediating variables. Addiction 116:8, pages 2094-2103.
Crossref
Mina M. Rizk, Sarah Herzog, Sanjana Dugad & Barbara Stanley. (2021) Suicide Risk and Addiction: The Impact of Alcohol and Opioid Use Disorders. Current Addiction Reports 8:2, pages 194-207.
Crossref
Andrew D. Peckham, Margaret L. Griffin, R. Kathryn McHugh & Roger D. Weiss. (2020) Depression history as a predictor of outcomes during buprenorphine-naloxone treatment of prescription opioid use disorder. Drug and Alcohol Dependence 213, pages 108122.
Crossref
Edward V. Nunes, Adam Bisaga, Evgeny Krupitsky, Narinder Nangia, Bernard L. Silverman, Sarah C. Akerman & Maria A. Sullivan. (2019) Opioid use and dropout from extended‐release naltrexone in a controlled trial: implications for mechanism. Addiction 115:2, pages 239-246.
Crossref
Moriah L. JacobsonCaroline A. BrowneIrwin Lucki. (2020) Kappa Opioid Receptor Antagonists as Potential Therapeutics for Stress-Related Disorders. Annual Review of Pharmacology and Toxicology 60:1, pages 615-636.
Crossref
Caroline A. Browne, Moriah L. Jacobson & Irwin Lucki. (2020) Novel Targets to Treat Depression: Opioid-Based Therapeutics. Harvard Review of Psychiatry 28:1, pages 40-59.
Crossref
Zill-e-Huma Latif, Jurate Šaltyte Benth, Kristin Klemmetsby Solli, Arild Opheim, Nikolaj Kunoe, Peter Krajci, Kamni Sharma-Haase & Lars Tanum. (2019) Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone. JAMA Psychiatry 76:2, pages 127.
Crossref
Kathleen M. Carroll, Charla Nich, Tami L. Frankforter, Sarah W. Yip, Brian D. Kiluk, Elise E. DeVito & Mehmet Sofuoglu. (2018) Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug and Alcohol Dependence 192, pages 264-270.
Crossref
Ahmed N. Hassan & Edward Nunes. (2018) Medication Treatments for Opioid Use Disorder: What Is the Impact on Mood and Mood Disorders?. Current Addiction Reports 5:3, pages 303-311.
Crossref
Stephen R. Holt & Daniel G. Tobin. (2018) Pharmacotherapy for Alcohol Use Disorder. Medical Clinics of North America 102:4, pages 653-666.
Crossref
Sarah J. BaileyStephen M. Husbands. (2018) Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?. Neuronal Signaling 2:2.
Crossref
Adam Bisaga, Paolo Mannelli, Maria A. Sullivan, Suzanne K. Vosburg, Peggy Compton, George E. Woody & Thomas R. Kosten. (2018) Antagonists in the medical management of opioid use disorders: Historical and existing treatment strategies. The American Journal on Addictions 27:3, pages 177-187.
Crossref
E. M. Krupitsky, E. E. Zvartau, E. A. Blokhina, E. V. Verbitskaya, V. Yu. Wahlgren, M. V. Tsoy-podosenin, N. M. Bushara, A. M. Burakov, D. V. Masalov, T. N. Romanova, A. A. Tiurina, V. Ya. Palatkin, T. S. Yaroslavtseva, G. Yu. Sulimov, A. Pecoraro & G. Woody. (2018) Anhedonia, depression, anxiety, and craving in opioid dependent patients stabilized on oral naltrexone or naltrexone implant. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 118:1, pages 26.
Crossref
Arthur Robin Williams, Vincent Barbieri, Kaitlyn Mishlen, Frances R. Levin, Edward V. Nunes, John J. Mariani & Adam Bisaga. (2017) Long-term follow-up study of community-based patients receiving XR-NTX for opioid use disorders. The American Journal on Addictions 26:4, pages 319-325.
Crossref
Abdulrahman Almatroudi, Stephen M Husbands, Christopher P Bailey & Sarah J Bailey. (2015) Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice. Journal of Psychopharmacology 29:7, pages 812-821.
Crossref
Eline R. Zaaijer, Lonneke van Dijk, Kora de Bruin, Anna E. Goudriaan, Laureen A. Lammers, Maarten W. J. Koeter, Wim van den Brink & Jan Booij. (2015) Effect of extended-release naltrexone on striatal dopamine transporter availability, depression and anhedonia in heroin-dependent patients. Psychopharmacology 232:14, pages 2597-2607.
Crossref
Shanthi Mogali, Nabil A. Khan, Esther S. Drill, Martina Pavlicova, Maria A. Sullivan, Edward Nunes & Adam Bisaga. (2015) Baseline characteristics of patients predicting suitability for rapid naltrexone induction. The American Journal on Addictions 24:3, pages 258-264.
Crossref
Margaret Haglund, Larissa Mooney, Michael Gitlin, Timothy Fong & John Tsuang. (2014) Vivitrol and Depression. Addictive Disorders & Their Treatment 13:3, pages 147-150.
Crossref
Richard J. Bodnar. (2012) Endogenous opiates and behavior: 2011. Peptides 38:2, pages 463-522.
Crossref
Sadie Geraghty & Carly Dixon. (2012) The use of naltrexone in pregnancy in opiate-dependent mothers. British Journal of Midwifery 20:7, pages 503-506.
Crossref
AR Lingford-Hughes, S Welch, L Peters & DJ Nutt. (2012) BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP. Journal of Psychopharmacology 26:7, pages 899-952.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.