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Research Articles

The Efficacy of Mirtazapine in the Treatment of Cocaine Dependence with Comorbid Depression

, M.D., , Ph.D., , M.D., , Ph.D., , R.N., , M.S., , B.A., , B.A. & , M.D. show all
Pages 181-186 | Published online: 05 Jan 2012

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Gustavo A. Angarita, Hasti Hadizadeh, Ignacio Cerdena & Marc N. Potenza. (2021) Can pharmacotherapy improve treatment outcomes in people with co-occurring major depressive and cocaine use disorders?. Expert Opinion on Pharmacotherapy 22:13, pages 1669-1683.
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Susana Barbosa Méndez & Alberto Salazar-Juárez. (2020) Mirtazapine decreased induction and expression of cocaine + nicotine-induced locomotor sensitisation in rats. The World Journal of Biological Psychiatry 21:8, pages 595-611.
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Zhenxiang Gao, T. John Winhusen, Maria Gorenflo, Udi E. Ghitza, Edward Nunes, Andrew J. Saxon, Todd Korthuis, Kathleen Brady, Sean Luo, Pamela B. Davis, David C. Kaelber & Rong Xu. (2023) Potential effect of antidepressants on remission from cocaine use disorder – A nationwide matched retrospective cohort study. Drug and Alcohol Dependence 251, pages 110958.
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Susana Barbosa-Méndez & Alberto Salazar-Juárez. (2023) Estradiol enhances the mirtazapine effects on the expression of cocaine-induced locomotor sensitization in female rats. Behavioural Pharmacology 34:6, pages 362-374.
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Nicole L. Hadler, Ilana S. Hairston & Deirdre A. Conroy. 2023. Encyclopedia of Sleep and Circadian Rhythms. Encyclopedia of Sleep and Circadian Rhythms 87 100 .
Dângela Layne Silva Lassi, André Malbergier, André Brooking Negrão, Lígia Florio, João P. De Aquino & João Maurício Castaldelli-Maia. (2022) Pharmacological Treatments for Cocaine Craving: What Is the Way Forward? A Systematic Review. Brain Sciences 12:11, pages 1546.
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Ricardo Nanni-Alvarado, Mario Gonzalez, Carlos Lima, Rodrigo Marín-Navarrete, Susana Barbosa-Méndez & Alberto Salazar-Juárez. (2021) Effect of Mirtazapine on Craving in Cocaine-Dependent Patients. International Journal of Mental Health and Addiction 20:5, pages 2770-2786.
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Andrew S. Huhn, Jennifer D. Ellis, Kelly E. Dunn, Dennis J. Sholler, Paula Tabaschek, Rachel Burns & Eric C. Strain. (2022) Patient-reported sleep outcomes in randomized-controlled trials in persons with substance use disorders: A systematic review. Drug and Alcohol Dependence 237, pages 109508.
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Leen Naji, Brittany Dennis, Tea Rosic, Wojtek Wiercioch, James Paul, Andrew Worster, Lehana Thabane & Zainab Samaan. (2022) Mirtazapine for the treatment of amphetamine and methamphetamine use disorder: A systematic review and meta-analysis. Drug and Alcohol Dependence 232, pages 109295.
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Aleksandra Dickov. (2022) Insomnia in addictive diseases and treatment of insomnia in opiate withdrawal crisis. Galenika Medical Journal 1:3, pages 14-21.
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Aniruddha Basu, Naveen Anand & Mrinmay Das. 2022. Sleep and Neuropsychiatric Disorders. Sleep and Neuropsychiatric Disorders 435 464 .
Mellar P. Davis. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1281 1309 .
Susana Barbosa-Méndez, Casandra López-Morado & Alberto Salazar-Juárez. (2021) Mirtazapine-induced decrease in cocaine sensitization is enhanced by environmental enrichment in rats. Pharmacology Biochemistry and Behavior 208, pages 173237.
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Mark K. Greenwald, Tabitha E.H. Moses & Timothy A. Roehrs. (2021) At the intersection of sleep deficiency and opioid use: mechanisms and therapeutic opportunities. Translational Research 234, pages 58-73.
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Susana Barbosa-Méndez, Luis Enrique Becerril-Villanueva, María Dolores Ponce-Regalado & Alberto Salazar-Juárez. 2021. The Neuroscience of Depression. The Neuroscience of Depression 401 410 .
Maaike van Veen & Roelof Risselada. 2021. Slaapstoornissen in de psychiatrie. Slaapstoornissen in de psychiatrie 331 361 .
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Susana Barbosa-Méndez, Katya Lorena Osorio-Santiago & Alberto Salazar-Juárez. (2020) Mirtazapine reduces the expression of cocaine-induced locomotor sensitization in male and female Wistar rats. Hormones and Behavior 125, pages 104817.
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Robert Suchting, Jin H. Yoon, Guadalupe G. San Miguel, Charles E. Green, Michael F. Weaver, Jessica N. Vincent, Gabriel R. Fries, Joy M. Schmitz & Scott D. Lane. (2020) Preliminary examination of the orexin system on relapse-related factors in cocaine use disorder. Brain Research 1731, pages 146359.
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Mellar P. Davis. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 29 .
Mauro Pettorruso, Giovanni Martinotti, Rita Santacroce, Chiara Montemitro, Fabrizio Fanella & Massimo di Giannantonio. (2019) rTMS Reduces Psychopathological Burden and Cocaine Consumption in Treatment-Seeking Subjects With Cocaine Use Disorder: An Open Label, Feasibility Study. Frontiers in Psychiatry 10.
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Jonathan Buchholz & Andrew J. Saxon. (2019) Medications to treat cocaine use disorders. Current Opinion in Psychiatry 32:4, pages 275-281.
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Susana Barbosa Méndez & Alberto Salazar-Juárez. (2019) Mirtazapine attenuates anxiety- and depression-like behaviors in rats during cocaine withdrawal. Journal of Psychopharmacology 33:5, pages 589-605.
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Akiko Shimamoto, Virginie Rappeneau, Havisha Munjal, Tonie Farris, Christopher Davis, Alicia Wilson, Malcolm Edwards, Cindy Moore, Collin Reynolds & Charles K. Meshul. (2018) Glutamate-Glutamine Transfer and Chronic Stress-Induced Sex Differences in Cocaine Responses. Neuroscience 391, pages 104-119.
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Susana Barbosa-Méndez & Alberto Salazar-Juárez. (2018) Mirtazapine attenuates nicotine-seeking behavior in rats. Journal of Psychopharmacology 32:9, pages 1010-1017.
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Subhajit Chakravorty, Ryan G. Vandrey, Sean He & Michael D. Stein. (2018) Sleep Management Among Patients with Substance Use Disorders. Medical Clinics of North America 102:4, pages 733-743.
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M. F. Lazenka & B. A. Hutsell. (2017) Preclinical Models for Assessment of Antidepressant Abuse Potential. Current Sexual Health Reports 9:4, pages 241-250.
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Susana Barbosa-Méndez, Maura Matus-Ortega & Alberto Salazar-Juárez. (2017) Synergistic interactions between mirtazapine and prazosin prevent the induction and expression of behavioral sensitization to cocaine in rats. Physiology & Behavior 180, pages 137-145.
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Susana Barbosa-Méndez, Phillipe Leff, Adriana Arías-Caballero, Ricardo Hernández-Miramontes, Gerardo Heinze & Alberto Salazar-Juárez. (2017) Mirtazapine attenuates cocaine seeking in rats. Journal of Psychiatric Research 92, pages 38-46.
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Susana Barbosa-Méndez, Maura Matus-Ortega, Anabel Flores-Zamora, Noe Jurado & Alberto Salazar-Juárez. (2017) Dose- and time-dependent effects of mirtazapine on the expression of cocaine-induced behavioral sensitization in rats. Psychiatry Research 254, pages 301-310.
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T.N. Andry, D. Shorter & T.R. Kosten. 2017. Encyclopedia of Behavioral Neuroscience, 2nd edition. Encyclopedia of Behavioral Neuroscience, 2nd edition 427 436 .
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Xavier Castells, Ruth Cunill, Clara Pérez-Mañá, Xavier Vidal & Dolors Capellà. (2016) Psychostimulant drugs for cocaine dependence. Cochrane Database of Systematic Reviews.
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Alberto Salazar-Juárez, Susana Barbosa-Méndez, Noe Jurado, Ricardo Hernández-Miramontes, Philippe Leff & Benito Antón. (2016) Mirtazapine prevents induction and expression of cocaine-induced behavioral sensitization in rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry 68, pages 15-24.
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Laurence Lalanne, Pierre-Eric Lutz, Benoit Trojak, Jean-Philippe Lang, Brigitte L. Kieffer & Elisabeth Bacon. (2016) Medications between psychiatric and addictive disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, pages 215-223.
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Robert E. Brutcher & Michael A. Nader. (2014) Effects of quetiapine treatment on cocaine self-administration and behavioral indices of sleep in adult rhesus monkeys. Psychopharmacology 232:2, pages 411-420.
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Brian S. Fulton. 2014. Drug Discovery for the Treatment of Addiction. Drug Discovery for the Treatment of Addiction 290 333 .
Wilfrid Noel Raby, Eric A. Rubin, Fatima Garawi, Wendy Cheng, Ella Mason, Lisa Sanfilippo, Stephanie Lord, Adam Bisaga, Efrat Aharonovich, Frances Levin, David McDowell & Edward V. Nunes. (2014) A randomized, double-blind, placebo-controlled trial of venlafaxine for the treatment of depressed cocaine-dependent patients. The American Journal on Addictions 23:1, pages 68-75.
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T. Celeste Napier, Amy A. Herrold & Harriet de Wit. (2013) Using conditioned place preference to identify relapse prevention medications. Neuroscience & Biobehavioral Reviews 37:9, pages 2081-2086.
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Daniel I. Brierley & Colin Davidson. (2012) Developments in harmine pharmacology — Implications for ayahuasca use and drug-dependence treatment. Progress in Neuro-Psychopharmacology and Biological Psychiatry 39:2, pages 263-272.
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Steven M. Graves, Roueen Rafeyan, Jeffrey Watts & T. Celeste Napier. (2012) Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: Evidence from the bench and the bedside. Pharmacology & Therapeutics 136:3, pages 343-353.
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