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Drug and Chemical Toxicology Volume 33, 2010 - Issue 2
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Research Article

Relations between toxicity and altered tissue distribution and urinary excretion of nicotine, cotinine, and hydroxycotinine after chronic oral administration of nicotine in rats

Ki Young Kim
,
Young-Joo LeeCollege of Pharmacy, Kyung Hee University, Seoul, Korea
,
Bong Chul ChungBioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, Seoul, Korea
,
Jongki HongCollege of Pharmacy, Kyung Hee University, Seoul, Korea
&
Byung Hwa JungBioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology, Seoul, KoreaCorrespondence[email protected]
Pages 166-172 | Received 13 May 2009, Accepted 21 Jul 2009, Published online: 22 Mar 2010

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Swapnali Halder, Jeffrey M. Lynch & Amy R. Pearce. (2013) The Multiple Bottle Effect Is Overridden in Male and Female Rats by Simultaneous Presentation of Two Oral Nicotine Solutions. The American Journal of Drug and Alcohol Abuse 39:3, pages 161-167.
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Mario Pellegatti. (2012) Preclinical in vivo ADME studies in drug development: a critical review. Expert Opinion on Drug Metabolism & Toxicology 8:2, pages 161-172.
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Mario Pellegatti & Sabrina Pagliarusco. (2011) Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review. Expert Opinion on Drug Metabolism & Toxicology 7:2, pages 137-146.
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Articles from other publishers (7)

Somayeh Rahimi Moghadam, Mahdi Afshari, Ali Ganjali & Mahmood Moosazadeh. (2020) Effect of occupational exposure to petrol and gasoline components on liver and renal biochemical parameters among gas station attendants, a review and meta-analysis. Reviews on Environmental Health 35:4, pages 517-530.
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Istvan Arany, Samuel Hall & Mehul Dixit. (2017) Age-dependent sensitivity of the mouse kidney to chronic nicotine exposure. Pediatric Research 82:5, pages 822-828.
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Istvan Arany, Anthony Carter, Samuel Hall, Tibor Fulop & Mehul Dixit. (2016) Coenzyme Q10 protects renal proximal tubule cells against nicotine-induced apoptosis through induction of p66shc-dependent antioxidant responses. Apoptosis 22:2, pages 220-228.
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Mahdi Jalali, Mohammad Reza Nikravesh & Mahmoud Moghaddam Dorafshani. (2016) Immunohistochemical Evaluation of the Effects of Nitrate in Drinking Water on Laminin Alpha-5 Expression in Rat Renal Glomeruli. Iranian Red Crescent Medical Journal 18:12.
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Gerald L. KennedyJr.Jr.. 2003. Patty's Toxicology. Patty's Toxicology 1 158 .
Paula L. Vieira-Brock, Eleanor I. Miller, Shannon M. Nielsen, Annette E. Fleckenstein & Diana G. Wilkins. (2011) Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography–tandem mass spectrometry. Journal of Chromatography B 879:30, pages 3465-3474.
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Istvan AranySamira Grifoni, Jeb S. ClarkEva Csongradi, Christine Maric & Luis A. Juncos. (2011) Chronic nicotine exposure exacerbates acute renal ischemic injury. American Journal of Physiology-Renal Physiology 301:1, pages F125-F133.
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