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Drug and Chemical Toxicology Volume 33, 2010 - Issue 1
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Research Article

A 90-day intravenous administration toxicity study of CaO-SiO2-P2O5-B2O3 glass-ceramics (BGS-7) in rat

Jae Hyup LeeDepartment of Orthopedic Surgery, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, SMG-SNUH Boramae Medical Center, Seoul, KoreaCorrespondence[email protected]
,
Hyun-Seung RyuResearch Center, Bioalpha, Seongnam, Korea
,
Jun-Hyuk SeoResearch Center, Bioalpha, Seongnam, Korea
,
Bong-Soon ChangDepartment of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul National University Hospital, Seoul, Korea
&
Choon-Ki LeeDepartment of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul National University Hospital, Seoul, Korea
Pages 38-47 | Received 07 Jul 2009, Accepted 23 Sep 2009, Published online: 08 Dec 2009

Citations (21)

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Jae Hyup Lee, Eui-Nam Lee & Sang Hyun Nam. (2014) The short-term effects of repetitive E. coli-derived rhBMP-2 administration through intravenous injection in rats. Drug and Chemical Toxicology 37:1, pages 40-47.
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Articles from other publishers (20)

Amina Gharbi, Hassane Oudadesse, Hafedh el Feki, Wissem Cheikhrouhou-Koubaa, Xanthippi Chatzistavrou, Julietta V. Rau, Jyrki Heinämäki, Iulian Antoniac, Nureddin Ashammakhi & Nabil Derbel. (2023) High Boron Content Enhances Bioactive Glass Biodegradation. Journal of Functional Biomaterials 14:7, pages 364.
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Jiwon Park, Sang-Min Park, Dae-Woong Ham, Jae-Young Hong, Ho-Joong Kim & Jin S. Yeom. (2023) Anterior Cervical Discectomy and Fusion Performed Using a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramic or Polyetheretherketone Cage Filled with Hydroxyapatite/β-Tricalcium Phosphate: A Prospective Randomized Controlled Trial. Journal of Clinical Medicine 12:12, pages 4069.
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Seungjun Ryu, Dal-Sung Ryu & Keun-Su Kim. (2023) Long-term results comparison after anterior cervical discectomy with BGS-7 spacer (NOVOMAX®-C) and allograft spacer: A prospective observational study. Frontiers in Bioengineering and Biotechnology 11.
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Ritesh Kumar, Ipsita Pattanayak, Pragyan Aparajita Dash & Smita Mohanty. (2023) Bioceramics: a review on design concepts toward tailor-made (multi)-functional materials for tissue engineering applications. Journal of Materials Science 58:8, pages 3460-3484.
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Byung-Taek Kwon, Ho-Joong Kim, Sanghoon Lee, Sang-Min Park, Dae-Woong Ham, Hyun-Jin Park, Ohsang Kwon & Jin S. Yeom. (2022) Feasibility and safety of a CaO-SiO2-P2O5-B2O3 bioactive glass ceramic spacer in posterior lumbar interbody fusion compared with polyetheretherketone cage: a prospective randomized controlled trial. Acta Neurochirurgica 165:1, pages 135-144.
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Chan Hee Shin, Sung Hwan Hwang, Jang Hun Kim, Sang Hoon Yoon & Byung-Kyu Cho. (2021) A Retrospective Comparative Study to Evaluate the Clinical Efficacy Using a Bioactive Glass Ceramic Spacer in Posterior Lumbar Interbody Fusion. Journal of Neurointensive Care 4:2, pages 58-64.
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Ashiq Ahamed, Liya Ge, Ke Zhao, Andrei Veksha, Johan Bobacka & Grzegorz Lisak. (2021) Environmental footprint of voltammetric sensors based on screen-printed electrodes: An assessment towards “green” sensor manufacturing. Chemosphere 278, pages 130462.
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Pinki Dey, Sumit Kumar Pal, Indranil Banerjee & Ritwik Sarkar. (2020) Effect of addition of B2O3 to the sol-gel synthesized 45S5 bioglass. Journal of the Australian Ceramic Society 56:4, pages 1309-1322.
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Ui-Lyong Lee, Jun-Young Lim, Sung-Nam Park, Byoung-Hun Choi, Hyun Kang & Won-Cheul Choi. (2020) A Clinical Trial to Evaluate the Efficacy and Safety of 3D Printed Bioceramic Implants for the Reconstruction of Zygomatic Bone Defects. Materials 13:20, pages 4515.
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Hyung Cheol Kim, Jae Keun Oh, Du Su Kim, Jeffrey S. Roh, Tae Woo Kim, Seong Bae An, Hyeong Seok Jeon, Dong Ah Shin, Seong Yi, Keung Nyun Kim, Do Heum Yoon & Yoon Ha. (2020) Comparison of the effectiveness and safety of bioactive glass ceramic to allograft bone for anterior cervical discectomy and fusion with anterior plate fixation. Neurosurgical Review 43:5, pages 1423-1430.
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Sehan Park, Dong-Ho Lee, Jaehyeon Seo, Kook-Jong Kim, Suk-Kyu Lee, Jae-Hong Park, Jae Hwan Cho, Jae-Woo Park, Chang Ju Hwang, Jae Jun Yang & Choon Sung Lee. (2020) Feasibility of CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramic Cage in Anterior Cervical Diskectomy and Fusion. World Neurosurgery 141, pages e358-e366.
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Jae Hyup Lee, Sun Ki Kim, Sung Shik Kang, Seung Jung Han, Choon-Ki Lee & Bong-Soon Chang. (2020) A Long-Term Follow-up, Multicenter, Comparative Study of the Radiologic, and Clinical Results Between a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramics (BGS-7) Intervertebral Spacer and Titanium Cage in 1-Level Posterior Lumbar Interbody Fusion. Clinical Spine Surgery: A Spine Publication 33:7, pages E322-E329.
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YongBok Kim, Jun Young Lim, Gi Hoon Yang, Jun-Hyuk Seo, Hyun-Seung Ryu & GeunHyung Kim. (2019) 3D-printed PCL/bioglass (BGS-7) composite scaffolds with high toughness and cell-responses for bone tissue regeneration. Journal of Industrial and Engineering Chemistry 79, pages 163-171.
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Jae Hyup Lee, Chang-Bae Kong, Jae Jun Yang, Hee-Jong Shim, Ki-Hyoung Koo, Jeehyoung Kim, Choon-Ki Lee & Bong-Soon Chang. (2016) Comparison of fusion rate and clinical results between CaO-SiO2-P2O5-B2O3 bioactive glass ceramics spacer with titanium cages in posterior lumbar interbody fusion. The Spine Journal 16:11, pages 1367-1376.
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Xiaoqing Wang, Lei Zhang, Xiurong Ke, Juncheng Wang, Guojing Yang, Xianyan Yang, Dongshuang He, Huifeng Shao, Yong He, Jianzhong Fu, Sanzhong Xu & Zhongru Gou. (2015) 45S5 Bioglass analogue reinforced akermanite ceramic favorable for additive manufacturing mechanically strong scaffolds. RSC Advances 5:124, pages 102727-102735.
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Jae Hyup Lee, Myong-Hyun Baek, Young Eun Kim, Jun-Hyuk Seo, Dong Ryul Song, Hyun-Seung Ryu, Choon-Ki Lee & Bong-Soon Chang. (2013) Finite Element Modeling of Stress Distribution in Intervertebral Spacers of Different Surface Geometries. Artificial Organs 37:11, pages 1014-1020.
Crossref
Jae Hyup Lee, Kug Sun Hong, Hae-Ri Baek, Jun-Hyuk Seo, Kyung Mee Lee, Hyun-Seung Ryu & Hyun-Kyung Lee. (2013) In Vivo Evaluation of CaO-SiO 2 -P 2 O 5 -B 2 O 3 Glass-Ceramics Coating on Steinman Pins . Artificial Organs 37:7, pages 656-662.
Crossref
Jae Hyup Lee, Jun-Hyuk Seo, Kyung Mee Lee, Hyun-Seung Ryu & Hae-Ri Baek. (2013) Fabrication and Evaluation of Osteoblastic Differentiation of Human Mesenchymal Stem Cells on Novel CaO-SiO 2 -P 2 O 5 -B 2 O 3 Glass-Ceramics . Artificial Organs 37:7, pages 637-647.
Crossref
Xianyan Yang, Lei Zhang, Xiaoyi Chen, Xiaoliang Sun, Guojing Yang, Xingzhong Guo, Hui Yang, Changyou Gao & Zhongru Gou. (2012) Incorporation of B2O3 in CaO-SiO2-P2O5 bioactive glass system for improving strength of low-temperature co-fired porous glass ceramics. Journal of Non-Crystalline Solids 358:9, pages 1171-1179.
Crossref
Jae Hyup Lee, Hwa Nam, Bong-Soon Chang, Choon-Ki Lee, Hyun-Seung Ryu & Jun-Hyuk Seo. (2011) Bioactive ceramic coating of cancellous screws improves the osseointegration in the cancellous bone. Journal of Orthopaedic Science 16:3, pages 291-297.
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