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Drug and Chemical Toxicology Volume 33, 2010 - Issue 4
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Research Article

Role of chlorogenic acid in the toxicity induced by Chinese herbal injections

Bao-qiu LiDepartment of Pharmacology, School of Pharmaceutical Sciences, Shandong University, Shandong, ChinaCorrespondence[email protected]
,
Xin DongShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Gui-qin YangShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Shi-hong FangShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Ji-you GaoShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Jian-xin ZhangShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Fang-min GuShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
,
Xiu-ming MiaoShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
&
Hua ZhaoShandong Hongli Laboratory Animal Experiment Co., Ltd., Shandong, China
 show all
Pages 415-420 | Received 30 Nov 2009, Accepted 16 Dec 2009, Published online: 16 Jun 2010

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Lei Song, Yating Zhou, Yuxia Zhai, Xiangxiang Huo, Mengying Chen, Hong Shi, Yingli Yu, Yue Zhang & Kun Zhou. (2023) Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats. Drug and Chemical Toxicology 46:3, pages 451-461.
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Articles from other publishers (18)

Haoyu Xue, Mengjuan Wei & Lili Ji. (2023) Chlorogenic acids: A pharmacological systematic review on their hepatoprotective effects. Phytomedicine 118, pages 154961.
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Yuan Gao, Ruijuan Qi, Xiaoyu Zhang, Xudong Xu, Yixin Han, Qiaoling Fei, Xiaojing Wang, Runlan Cai, Guibo Sun & Yun Qi. (2020) Qing-Kai-Ling Injection Induces Immediate Hypersensitivity Reaction via the Activation of Anaphylatoxin C3. Frontiers in Pharmacology 10.
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Tsou, Hu, Yang, Yan & Lin. (2019) Potential Oral Health Care Agent from Coffee Against Virulence Factor of Periodontitis. Nutrients 11:9, pages 2235.
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Bi-li Wu, Wen-xi He, Meng Ke, Xiao-fang Shang-Guan, Guo-fang He & Rui Huang. (2018) A Retrospective Analysis on 1330 Adverse Event Reports of Qingkailing in China: Further Perception of Its Risks and Rational Use. Current Medical Science 38:6, pages 1103-1108.
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Wen‑Yuan Du, Ying Xiao, Jian‑Jing Yao, Zhe Hao & Yu‑Bin Zhao. (2018) Chlorogenic acid in the oxidative stress injury triggered by Shuang‑Huang‑Lian injection. Experimental and Therapeutic Medicine.
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Yitong Liu. (2018) Incorporation of absorption and metabolism into liver toxicity prediction for phytochemicals: A tiered in silico QSAR approach. Food and Chemical Toxicology 118, pages 409-415.
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Jiayu Zhang, Shifeng Wang, Lulu Xu, Qiao Zhang, Zhanpeng Shang, Yanling Zhang, Qinghua Wu, Shiyou Li & Yanjiang Qiao. (2017) Multiple Perspectives of Qingkailing Injection-Fraction-Single Compound in Revealing the Hepatotoxicity of Baicalin and Hyodeoxycholic Acid. Journal of Ethnopharmacology.
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Qiannan Zhang, Hui Yang, Yongning Li, Haibo Liu & Xudong Jia. (2017) Toxicological evaluation of ethanolic extract from Stevia rebaudiana Bertoni leaves: Genotoxicity and subchronic oral toxicity. Regulatory Toxicology and Pharmacology 86, pages 253-259.
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Yan Du, Jie Han, Shi-an Sun, Zheng Li, Fang-xiu Yang, Lu-lu Dong, Dong-zhi Yang & Dao-quan Tang. (2016) Simultaneous Determination of 11 Components in Yinzhihuang Preparations and Their Constituent Herbs by High-Performance Liquid Chromatography with Diode Array Detector. Journal of Chromatographic Science 54:4, pages 625-632.
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Zhixin Zhang, Lingling Qin, Long Peng, Qingqing Zhang, Qing Wang, Zhiwei Lu, Yuelin Song & Xiaoyan Gao. (2016) Pharmacokinetic-Pharmacodynamic Modeling to Study the Antipyretic Effect of Qingkailing Injection on Pyrexia Model Rats. Molecules 21:3, pages 317.
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Shasha Jin, Cuiqing Chang, Lantao Zhang, Yang Liu, Xianren Huang & Zhimin Chen. (2015) Chlorogenic Acid Improves Late Diabetes through Adiponectin Receptor Signaling Pathways in db/db Mice. PLOS ONE 10:4, pages e0120842.
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Ludi Jiang, Yusu He & Yanling Zhang. (2014) Prediction of hepatotoxicity of traditional Chinese medicine compounds by support vector machine approach. Prediction of hepatotoxicity of traditional Chinese medicine compounds by support vector machine approach.
Long Peng, Xiaoyan Gao, Yuelin Song, Longshan Zhao, Mingxing Guo, Jiankun Su, Li Zhang & Haiyu Liu. (2014) A rapid and sensitive UPLC-MS/MS method for quantification of two caffeoylquinic acids and four main active components in rat plasma after an intravenous administration of Qingkailing injection and its application to a pharmacokinetic study. Biomedical Chromatography 28:5, pages 601-609.
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Gui Nan Xiao, Qing Ping Sun & Hao An Chen. (2013) Contribution of serum IL-4 and IgE to the early prediction of allergic reactions induced by chlorogenic acid. European Journal of Pharmacology 699:1-3, pages 1-5.
Crossref
Jinling Ma, Yutang Wang, Meng Gao, Qingyi Meng & Jie Liu. (2012) Adverse drug reactions as the cause of emergency department admission of patients aged 80years and older. European Journal of Internal Medicine 23:6, pages e162-e163.
Crossref
Cen Xie, Dafang Zhong & Xiaoyan Chen. (2012) Identification of the ortho -Benzoquinone Intermediate of 5- O -Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations . Drug Metabolism and Disposition 40:8, pages 1628-1640.
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Yongshen Ren, Ping Zhang, Dan Yan, Jiabo Wang, Xiaoxi Du & Xiaohe Xiao. (2011) A strategy for the detection of quality fluctuation of a Chinese herbal injection based on chemical fingerprinting combined with biological fingerprinting. Journal of Pharmaceutical and Biomedical Analysis 56:2, pages 436-442.
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. (2011) RECENT LITERATURE. Focus on Alternative and Complementary Therapies 16:1, pages 86-93.
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