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Drug and Chemical Toxicology Volume 35, 2012 - Issue 2
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Research Article

Promoting effects of chemical permeation enhancers on insulin permeation across TR146 cell model of buccal epithelium in vitro

Xiao-yan XueDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Ying ZhouDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Ying-ying ChenDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Jing-ru MengDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Min JiaDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Zheng HouDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Hui BaiDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, China
,
Xing-gang MaoDepartment of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi’an, China
&
Xiao-xing LuoDepartment of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi’an, ChinaCorrespondence[email protected]
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Pages 199-207 | Received 15 Apr 2011, Accepted 11 May 2011, Published online: 18 Aug 2011

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Santosh Bashyal, Jo-Eun Seo, Taekwang Keum, Gyubin Noh, Young Wook Choi & Sangkil Lee. (2018) Facilitated permeation of insulin across TR146 cells by cholic acid derivatives-modified elastic bilosomes. International Journal of Nanomedicine 13, pages 5173-5186.
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Javier O. Morales & Jason T. McConville. (2014) Novel strategies for the buccal delivery of macromolecules. Drug Development and Industrial Pharmacy 40:5, pages 579-590.
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Elizabeth Ojewole, Rahul Kalhapure, Krishnacharya Akamanchi & Thirumala Govender. (2014) Novel oleic acid derivatives enhance buccal permeation of didanosine. Drug Development and Industrial Pharmacy 40:5, pages 657-668.
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Articles from other publishers (9)

Adriana Fantini, Luca Giulio, Andrea Delledonne, Silvia Pescina, Cristina Sissa, Sara Nicoli, Patrizia Santi & Cristina Padula. (2022) Buccal Permeation of Polysaccharide High Molecular Weight Compounds: Effect of Chemical Permeation Enhancers. Pharmaceutics 15:1, pages 129.
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Apipa Wanasathop, Priya B Patel, Hyojin A. Choi & S. Kevin Li. (2021) Permeability of Buccal Mucosa. Pharmaceutics 13:11, pages 1814.
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Yi-gong Guo & Anubhav Pratap Singh. (2019) Emerging strategies for enhancing buccal and sublingual administration of nutraceuticals and pharamaceuticals. Journal of Drug Delivery Science and Technology 52, pages 440-451.
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Affiong Iyire, Maryam Alaayedi & Afzal R. Mohammed. (2016) Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers. Scientific Reports 6:1.
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Neha Shrestha, Francisca Araújo, Bruno Sarmento, Jouni Hirvonen & Hélder A. Santos. 2016. Concepts and Models for Drug Permeability Studies. Concepts and Models for Drug Permeability Studies 31 40 .
Ni Zeng, Nathalie Mignet, Gilles Dumortier, Elodie Olivier, Johanne Seguin, Marc Maury, Daniel Scherman, Patrice Rat & Vincent Boudy. (2015) Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans-epithelial permeability evaluations using TR146 human buccal epithelial cell line. International Journal of Pharmaceutics 495:2, pages 1028-1037.
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Xiao-Yan Xue, Xing-Gang Mao, Zhi Li, Zhou Chen, Ying Zhou, Zheng Hou, Ming-Kai Li, Jing-Ru Meng & Xiao-Xing Luo. (2015) A potent and selective antimicrobial poly(amidoamine) dendrimer conjugate with LED209 targeting QseC receptor to inhibit the virulence genes of gram negative bacteria. Nanomedicine: Nanotechnology, Biology and Medicine 11:2, pages 329-339.
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Camilla Sander, Hanne Mørck Nielsen & Jette Jacobsen. (2013) Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement. International Journal of Pharmaceutics 458:2, pages 254-261.
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Xiaoyan Xue, Xiaoqing Chen, Xinggang Mao, Zheng Hou, Ying Zhou, Hui Bai, Jingru Meng, Fei Da, Guojun Sang, Yukun Wang & Xiaoxing Luo. (2012) Amino-Terminated Generation 2 Poly(amidoamine) Dendrimer as a Potential Broad-Spectrum, Nonresistance-Inducing Antibacterial Agent. The AAPS Journal 15:1, pages 132-142.
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