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Drug and Chemical Toxicology Volume 3, 1980 - Issue 2
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Research Article

Eighteen Month Oral Study of Aspirin, Phenacetin and Caffeine in C57BL/6 Mice

A. W. Macklin Wellcome Research Laboratories, Research Triangle Park, NC, 27709
&
R. J. Szot Wellcome Research Laboratories, Research Triangle Park, NC, 27709
Pages 135-163 | Published online: 27 Sep 2008

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P. Nawrot, S. Jordan, J. Eastwood, J. Rotstein, A. Hugenholtz & M. Feeley. (2003) Effects of caffeine on human health. Food Additives & Contaminants 20:1, pages 1-30.
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Peter H. Bach, William O. Berndt, Elizabeth Delzell, Ulrich Dubach, William F. Finn, Johannes M. Fox, Robert Hess, Paul Michielsen, Dale P. Sandler, Benjamin Trump & Gary Williams. (1998) A Safety Assessment of Fixed Combinations of Acetaminophen and Acetylsalicylic Acid, Coformulated with Caffeine. Renal Failure 20:6, pages 749-762.
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RickG. Schnellmann. (1998) Analgesic nephropathy in rodents. Journal of Toxicology and Environmental Health, Part B 1:1, pages 81-90.
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Neill J. Gregg, Michael E. C. Robbins, John W. Hopewell & Peter H. Bach. (1990) The Effect of Acetaminophen on Pig Kidneys with a 2-Bromoethanamine-Induced Papillary Necrosis. Renal Failure 12:3, pages 157-163.
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DavidY. Lai & Yin‐tak Woo. (1987) Naturally occurring carcinogens: An overview . Environmental Carcinogenesis Reviews 5:2, pages 121-173.
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Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 1. CRC Critical Reviews in Toxicology 15:3, pages 217-329.
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Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 2. CRC Critical Reviews in Toxicology 15:4, pages 331-439.
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Articles from other publishers (22)

Joost P.M. Melis, Ewoud N. Speksnijder, Raoul V. Kuiper, Daniela C.F. Salvatori, Mirjam M. Schaap, Saskia Maas, Joke Robinson, Aart Verhoef, Jan van Benthem, Mirjam Luijten & Harry van Steeg. (2013) Detection of genotoxic and non-genotoxic carcinogens in Xpc−/−p53+/− mice. Toxicology and Applied Pharmacology 266:2, pages 289-297.
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Peter Greaves. 2012. Histopathology of Preclinical Toxicity Studies. Histopathology of Preclinical Toxicity Studies 537 614 .
Peter Greaves. 2007. Histopathology of Preclinical Toxicity Studies. Histopathology of Preclinical Toxicity Studies 570 660 .
F Burdan, Z Siezieniewska & Z Urbanowicz. (2016) Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver. Human & Experimental Toxicology 20:11, pages 569-575.
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Alvan R. Feinstein, Lothar A.J. Heinemann, Gary C. Curhan, Elizabeth Delzell, Paul J. DeSchepper, Johannes M. Fox, Helmut Graf, Friedrich C. Luft, Paul Michielsen, Michael J. Mihatsch, Samy Suissa, Fokko van der Woude & Stefan Willich. (2000) Relationship between nonphenacetin combined analgesics and nephropathy: A review. Kidney International 58:6, pages 2259-2264.
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Peter Greaves. 2000. Histopathology of Preclinical Toxicity Studies. Histopathology of Preclinical Toxicity Studies 545 626 .
Peter H. Bach & Nguyen Thi Kim Thanh. (2016) Renal Papillary Necrosis—40 Years On. Toxicologic Pathology 26:1, pages 73-91.
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Jill W. Verlander. (2016) Normal Ultrastructure of the Kidney and Lower Urinary Tract. Toxicologic Pathology 26:1, pages 1-17.
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Ekkehard Kunze. 1998. Urinary System. Urinary System 331 368 .
J. M. Fox. (1995) Kombinationsarzneimittel aus Paracetamol plus Acetylsalicylsäure: Nutzen und RisikenCombination analgesics consisting of paracetamol plus acetylsalicylic acid: benefits and risks. Der Schmerz 9:6, pages 273-285.
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Johannes M. Fox. (1988) Coffein plus Analgetika—eine sinnvolle KombinationCaffeine plus analgesics—a significant combination. Der Schmerz 2:4, pages 183-197.
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PETER H. BACH & NEILL J. GREGG. 1988. International Review of Experimental Pathology. International Review of Experimental Pathology 1 54 .
YIN-TAK WOO, DAVID Y. LAI, JOSEPH C. ARCOS & MARY F. ARGUS. 1988. Natural, Metal, Fiber, and Macromolecular Carcinogens. Natural, Metal, Fiber, and Macromolecular Carcinogens 3 616 .
P. H. Bach & M. S. Feldman. 1987. Side-Effects of Anti-Inflammatory Drugs. Side-Effects of Anti-Inflammatory Drugs 393 413 .
Hugh E. Black. (2016) Renal Toxicity of Non-Steroidal Anti-Inflammatory Drugs. Toxicologic Pathology 14:1, pages 83-90.
Crossref
E. Kunze. 1986. Urinary System. Urinary System 291 310 .
Peter H. Bach & T.L. Hardy. (1985) Relevance of animal models to analgesic-associated renal papillary necrosis in humans. Kidney International 28:4, pages 605-613.
Crossref
U. Mohr, J. Althoff, M.B. Ketkar, P. Conradt & K. Morgareidge. (1984) The influence of caffeine on tunour indicidence in Sprague-Dawley rats. Food and Chemical Toxicology 22:5, pages 377-382.
Crossref
K.D. Rainsford. 1984. Aspirin and the Salicylates. Aspirin and the Salicylates 148 271 .
H. C. Grice. 1984. Caffeine. Caffeine 201 220 .
MICHAEL P. LACHANCE. (2007) THE PHARMACOLOGY AND TOXICOLOGY OF CAFFEINE. Journal of Food Safety 4:2, pages 71-112.
Crossref
Keisuke Nakanishi, Yasushi Kurata, Masato Oshima, Shoji Fukushima & Nobuyuki Ito. (2006) Carcinogenicity of phenacetin: Long‐term feeding study in B6C3F 1 mice . International Journal of Cancer 29:4, pages 439-444.
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