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Drug and Chemical Toxicology Volume 17, 1994 - Issue 3
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Research Article

Immunotoxicity of 180 Day Exposure to Polydimethylsiloxane (Silicone) Fluid, Gel and Elastomer and Polyurethane Disks in Female B6C3F1 Mice

S. G. Bradley Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298; Microbiology and Immunology Virginia Commonwealth University, Richmond, VA, 23298
,
K. L. White Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298; Biomedical Engineering Virginia Commonwealth University, Richmond, VA, 23298
,
J. A. McCay Biostatistics Virginia Commonwealth University, Richmond, VA, 23298
,
R. D. Brown Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298
,
D. L. Musgrove Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298
,
S. Wilson Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298
,
M. Stern Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298
,
M. I. Luster Systemic Toxicology Branch, National Toxicology Program, National Institures of Environmental Health Sciences, Research Triangle ParkNC, 27709
&
A. E. Munson Departments of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298
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Pages 221-269 | Published online: 27 Sep 2008

Citations (16)

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Read on this site (2)

K. L. White & P. C. Klykken. (1998) The Non-Specific Binding of Immunoglobulins to Silicone Implant Materials: The Lack of a Detectable Silicone Specific Antibody. Immunological Investigations 27:4-5, pages 221-235.
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JackW. Snyder. (1997) Silicone breast implants. Journal of Legal Medicine 18:2, pages 133-220.
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Articles from other publishers (14)

Sang‐Tae Kim. 2003. Patty's Toxicology. Patty's Toxicology 1 32 .
Zhi Ting Ye, Yung-Min Pai, Chih-Hao Lin, Lung-Chien Chen, Hong Thai Nguyen & Hsiang-Chen Wang. (2019) Nanoparticle-Doped Polydimethylsiloxane Fluid Enhances the Optical Performance of AlGaN-Based Deep-Ultraviolet Light-Emitting Diodes. Nanoscale Research Letters 14:1.
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D. Srinivasa, B. Blumenauer & M.W. Clemens. 2017. Nanotechnology in Cancer. Nanotechnology in Cancer 71 85 .
Bailus WalkerJr.Jr. & Lynette D. Stokes. 2001. Patty's Toxicology. Patty's Toxicology 891 916 .
Colleen E McLoughlin, Matthew J Smith, Wimolnut Auttachoat, Gary L Bowlin & Kimber L WhiteJrJr. (2012) Evaluation of innate, humoral and cell-mediated immunity in mice following in vivo implantation of electrospun polycaprolactone . Biomedical Materials 7:3, pages 035015.
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Sandra Franz, Stefan Rammelt, Dieter Scharnweber & Jan C. Simon. (2011) Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials. Biomaterials 32:28, pages 6692-6709.
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Frank L. Bowling, Stuart A. Metcalfe, Stephanie Wu, Andrew J. M. Boulton & David G. Armstrong. (2010) Liquid Silicone to Mitigate Plantar Pedal Pressure: A Literature Review. Journal of Diabetes Science and Technology 4:4, pages 846-852.
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Matthew J. Smith, Donna C. Smith, Kimber L. WhiteJr.Jr. & Gary L. Bowlin. (2007) Immune Response Testing of Electrospun Polymers: An Important Consideration in the Evaluation of Biomaterials. Journal of Engineered Fibers and Fabrics 2:2, pages 155892500700200.
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Prasad Venkatram Shastri. (2002) Toxicology of polymers for implant contraceptives for women. Contraception 65:1, pages 9-13.
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Bailus Walker & Laureen Burton. 2001. Patty's Toxicology. Patty's Toxicology.
Kimber L. WhiteJr.Jr.. (1998) Silicone Gel and Animal Models of Autoimmune Disease. Clinical Immunology and Immunopathology 87:3, pages 205-206.
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S. D. Wilson & A. E. Munson. 1996. Immunology of Silicones. Immunology of Silicones 199 208 .
P. C. Klykken & K. L. WhiteJr.Jr.. 1996. Immunology of Silicones. Immunology of Silicones 113 121 .
David H. DeHeer, Scott R. Owens & Alfred B. Swanson. (1995) The host response to silicone elastomer implants for small joint arthroplasty. The Journal of Hand Surgery 20:3, pages S101-S109.
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