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Archives of Andrology
Journal of Reproductive Systems
Volume 5, 1980 - Issue 3
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Original Article

Interaction of Lipids with the Plasma Membrane of Sperm Cells. I. The Antifertilization Action of Cholesterol

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Pages 249-254 | Accepted 26 Feb 1980, Published online: 09 Jul 2009

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Read on this site (6)

F. Vignon, M. H. Koll-back, A. Clavert & C. Cranz. (1989) Lipid Composition of Human Seminal Plasma. Archives of Andrology 22:1, pages 49-53.
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M. Balerna, G. M. Colpi, A. Campana, L. Roveda, A. Tommasini-degna & A. Zanollo. (1982) High-Resolution Protein Patterns of Human Expressed Prostatic Secretion: A New Tool for the Diagnosis of Prostatitis. Archives of Andrology 8:2, pages 97-105.
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Articles from other publishers (56)

Francisco M. Pinto, Ainize Odriozola, Luz Candenas & Nerea Subirán. (2023) The Role of Sperm Membrane Potential and Ion Channels in Regulating Sperm Function. International Journal of Molecular Sciences 24:8, pages 6995.
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Shuo Han, Xiang-Ping Chu, Ryan Goodson, Prae Gamel, Sophia Peng, Joshua Vance & Shizhen Wang. (2022) Cholesterol inhibits human voltage-gated proton channel hHv1. Proceedings of the National Academy of Sciences 119:36.
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María José Contreras, María Elena Arias, Mauricio Silva, Paulina Cabrera & Ricardo Felmer. (2022) Effect of cholestanol and cholesterol-loaded cyclodextrin on stallion sperm function and capacitation post-cryopreservation. Theriogenology 189, pages 1-10.
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Shuwen Shan, Fangzheng Xu, Marc Hirschfeld & Bertram Brenig. (2021) Sperm Lipid Markers of Male Fertility in Mammals. International Journal of Molecular Sciences 22:16, pages 8767.
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Ahmad Yar Qamar, Xun Fang, Seonggyu Bang, Feriel Yasmine Mahiddine, Min Jung Kim & Jongki Cho. 2021. Role of Exosomes in Biological Communication Systems. Role of Exosomes in Biological Communication Systems 115 139 .
P Peruma. (2018) Low density lipoprotein in cryopreservation of semen. Asian Pacific Journal of Reproduction 7:3, pages 103.
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P Perumal, SK Srivastava, SK Ghosh, KK Baruah, S Bag, JS Rajoria, K Kumar, C Rajkhowa, M Pande & N Srivastava. (2016) Effects of low-density lipoproteins as additive on quality parameters and oxidative stress following cryopreservation of mithun ( Bos frontalis ) spermatozoa . Reproduction in Domestic Animals 51:5, pages 708-716.
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J.S. Rajoriya, J.K. Prasad, S.S. Ramteke, P. Perumal, S.K. Ghosh, M. Singh, Megha Pande & N. Srivastava. (2016) Enriching membrane cholesterol improves stability and cryosurvival of buffalo spermatozoa. Animal Reproduction Science 164, pages 72-81.
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R. J. Aitken & B. Nixon. (2013) Sperm capacitation: a distant landscape glimpsed but unexplored. Molecular Human Reproduction 19:12, pages 785-793.
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R. Sullivan & F. Saez. (2013) Epididymosomes, prostasomes, and liposomes: their roles in mammalian male reproductive physiology. Reproduction 146:1, pages R21-R35.
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Alfredo Medrano, Paul F Watson & William V Holt. (2012) Investigation of pig sperm plasma membrane reorganization using progesterone-albumin-fluorescein probes. Asian Pacific Journal of Reproduction 1:1, pages 27-33.
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C.H. Oliveira, A.B. Vasconcelos, F.A. Souza, O.A. Martins-Filho, M.X. Silva, F.C. Varago & M.A. Lagares. (2010) Cholesterol addition protects membrane intactness during cryopreservation of stallion sperm. Animal Reproduction Science 118:2-4, pages 194-200.
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Hannah L. Galantino‐Homer, Wen‐xian Zeng, Susan O. Megee, Modesty Dallmeyer, Dawna Voelkl & Ina Dobrinski. (2006) Effects of 2‐hydroxypropyl‐β‐cyclodextrin and cholesterol on porcine sperm viability and capacitation status following cold shock or incubation. Molecular Reproduction and Development 73:5, pages 638-650.
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Cesare Castellini, Raffaella Cardinali, Alessandro Dal Bosco, Alba Minelli & Oliva Camici. (2006) Lipid composition of the main fractions of rabbit semen. Theriogenology 65:4, pages 703-712.
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Hanae Rejraji & Joeël R. Drevet. (2004) Sécrétions apocrines dans le tractus génital mâle: Roles potentiels dans la maturation des gamètesApocrine secretions in the male genital tract: putative roles in sperm maturation. Andrologie 14:1, pages 22-33.
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Cuigi Wu, Tomas Stojanov, Omar Chami, Santoshi Ishii, Takao Shimuzu, Aiging Li & Chris O'Neill. (2001) Evidence for the Autocrine Induction of Capacitation of Mammalian Spermatozoa. Journal of Biological Chemistry 276:29, pages 26962-26968.
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F. R. Ochsendorf, D. Rinne, J. Fuchs, P. Such & G. Zimmer. (2009) Electron paramagnetic resonance spectroscopy for the investigation of the fluidity of human spermatozoa plasma membranes: a feasibility study. Andrologia 32:3, pages 169-177.
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Naomichi Okamura, Sachiko Kiuchi, Michiko Tamba, Takayuki Kashima, Shinsuke Hiramoto, Tadashi Baba, Francoise Dacheux, Jean-Louis Dacheux, Yoshiki Sugita & Yin-Zhe Jin. (1999) A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1438:3, pages 377-387.
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I. Thérien, R. Moreau & P. Manjunath. (1998) Major Proteins of Bovine Seminal Plasma and High-Density Lipoprotein Induce Cholesterol Efflux from Epididymal Sperm1. Biology of Reproduction 59:4, pages 768-776.
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Erma Z. Drobnis. 1997. Male Infertility and Sexual Dysfunction. Male Infertility and Sexual Dysfunction 54 82 .
Nicholas L. Cross. (1996) Effect of cholesterol and other sterols on human sperm acrosomal responsiveness. Molecular Reproduction and Development 45:2, pages 212-217.
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Pablo E. Visconti, Grace D. Moore, Janice L. Bailey, Pierre Leclerc, Stephanie A. Connors, Dieyun Pan, Patricia Olds-Clarke & Gregory S. Kopf. (1995) Capacitation of mouse spermatozoa: II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway. Development 121:4, pages 1139-1150.
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Pablo E. Visconti, Janice L. Bailey, Grace D. Moore, Dieyun Pan, Patricia Olds-Clarke & Gregory S. Kopf. (1995) Capacitation of mouse spermatozoa: I. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 121:4, pages 1129-1137.
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Robin S. King, Sharon H. Anderson & Gary J. Killian. (2013) Effect of Bovine Oviductal Estrus‐Associated Protein on the Ability of Sperm to Capacitate and Fertilize Oocytes. Journal of Andrology 15:5, pages 468-478.
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SUSAN BENOFF, GEORGE W. COOPER, IAN HURLEY, FRANCINE S. MANDEL & DAVID L. ROSENFELD. (1993) Antisperm Antibody Binding to Human Sperm Inhibits Capacitation Induced Changes in the Levels of Plasma Membrane Sterols. American Journal of Reproductive Immunology 30:2-3, pages 113-130.
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Marina Diaz‐Fontdevila & Eduardo Bustos‐Obregon. (2005) Cholesterol and polyunsaturated acid enriched diet: Effect on kinetics of the acrosome reaction in rabbit spermatozoa. Molecular Reproduction and Development 35:2, pages 176-180.
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J. C. Andrews, J. G. Howard, B. D. Bavister & D. E. Wildt. (2005) Sperm capacitation in the domestic cat ( Felis catus ) and leopard cat ( Felis bengalensis ) as studied with a salt‐stored zona pellucida penetration assay . Molecular Reproduction and Development 31:3, pages 200-207.
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Naohiko Seki, Yoshiro Toyama & Toshio Nagano. (1992) Changes in the distribution of filipin-sterol complexes in the boar sperm head plasma membrane during epididymal maturation and in the uterus. The Anatomical Record 232:2, pages 221-230.
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BAYARD T. STOREY. (1991) Sperm Capacitation and the Acrosome Reaction. Annals of the New York Academy of Sciences 637:1 The Male Germ, pages 459-473.
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M. Klemm & W. Engel. (2009) On the capacity of mouse spermatozoa for spontaneous acrosome reaction in the male and female genital tract. Andrologia 23:6, pages 427-433.
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P.P. Watson, P.S. Jones & J.M. Plummer. (1991) A quantitative comparison of the spontaneous and ionophore-induced acrosome reaction in ejaculated ram spermatozoa: the effects of temperature, time and individual. Animal Reproduction Science 24:1-2, pages 93-108.
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Bayard T. Storey & Gregory S. Kopf. 1991. A Comparative Overview of Mammalian Fertilization. A Comparative Overview of Mammalian Fertilization 167 216 .
Judy M. Clark & James K. Koehler. (2005) Observations of hamster sperm‐egg fusion in freeze‐fracture replicas including the use of filipin as a sterol marker. Molecular Reproduction and Development 27:4, pages 351-365.
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M. Rosselli, M. Marchini, G. Soldati, A. Campana & M. Balerna. (2009) Removal of sperm-coat from human spermatozoa by interaction with cervical mucus or a capacitating medium: Entfernung des Sperm-Coats bei menschlichen Spermien durch Interaktion mit Zervixschleim oder mit einem kapazitierenden Medium. Andrologia 22:6, pages 543-547.
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D. Montagnon, B. Valtat, F. Vignon & M. H. Koll-Back. (2009) Secretory proteins of human seminal vesicles and their relationship to lipids and sugars: Sekretorische Proteine der menschlichen Bläschendrüse und ihre Beziehungen zu Lipiden und Zuckern. Andrologia 22:S1, pages 193-205.
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B. J. BLUE, A.O. McKINNON, E. L. SQUIRES, G. E. SEIDELJR.JR. & K. T. MUSCARI. (2010) Capacitation of stallion spermatozoa and fertilisation of equine oocytes in vitro. Equine Veterinary Journal 21:S8, pages 111-116.
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M. Awano, A. Kawaguchi, M. Morisaki & H. Mohri. (1989) Identification of cholesta-7,24-dien-3β-ol and desmosterol in hamster cauda epididymal spermatozoa. Lipids 24:7, pages 662-664.
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Jane C. Andrews & Barry D. Bavister. (2005) Capacitation of hamster spermatozoa with the divalent cation chelators D‐penicillamine, L‐histidine, and L‐cysteine in a protein‐free culture medium. Gamete Research 23:2, pages 159-170.
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JUAN G. ALVAREZ, MICHAEL A. LEE, RENATO V. IOZZO, ISABEL LOPEZ, JOSEPH C. TOUCHSTONE & BAYARD T. STOREY. (2013) Ethanol Accelerates Acrosomal Loss in Human Spermatozoa. Journal of Andrology 9:6, pages 357-366.
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Eduardo Ehrenwald, John E. Parks & Robert H. Foote. (2005) Cholesterol efflux from bovine sperm: II. Effect of reducing sperm cholesterol on penetration of zona‐free hamster and in vitro matured bovine ova. Gamete Research 20:4, pages 413-420.
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MARCELO CABADA, BERNABÉ BLOJ, LUISA P. de ORTIZ, JORGE N. VALZ‐GIANINET & MARINA DIAZ FONTDEVILA. (2008) Effect of Phosphatidylcholine on Acrosome Breakdown and Fertilizing Capacity of Amphibian Spermatozoa. Development, Growth & Differentiation 26:6, pages 515-523.
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A. Arcidiacono, H. Walt, A. Campana & M. Balerna. (2008) The use of Percoll gradients for the preparation of subpopulations of human spermatozoa. International Journal of Andrology 6:5, pages 433-445.
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Christopher P. Carron & Frank J. Longo. (1983) Filipin/sterol complexes in fertilized and unfertilized sea urchin egg membranes. Developmental Biology 99:2, pages 482-488.
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Brian K. Davis & Nelida V. Davis. (1983) Binding by glycoproteins of seminal plasma membrane vesicles accelerates decapacitation in rabbit spermatozoa. Biochimica et Biophysica Acta (BBA) - Biomembranes 727:1, pages 70-76.
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