Advanced search
Publication Cover
Journal of Neurogenetics Volume 28, 2014 - Issue 1-2: From Genes to Behavioral Diseases: Neurogenetics of Psychiatric and Neurological Disorders . Guest Editor: Wei-Dong Yao
Submit an article Journal homepage
707
Views
38
CrossRef citations to date
0
Altmetric
Review Article

The Emerging Roles of MicroRNAs in the Pathogenesis of Frontotemporal Dementia–Amyotrophic Lateral Sclerosis (FTD-ALS) Spectrum Disorders

Eduardo GasconDepartment of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
&
Fen-Biao GaoDepartment of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USACorrespondence[email protected]
Pages 30-40 | Received 18 Oct 2013, Accepted 12 Dec 2013, Published online: 10 Feb 2014

Citations (38)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Francesca Svetoni, Paola Frisone & Maria Paola Paronetto. (2016) Role of FET proteins in neurodegenerative disorders. RNA Biology 13:11, pages 1089-1102.
Read now
Wei-Dong Yao & Chun-Fang Wu. (2014) Exploring the Genetic Underpinnings of Brain and Behavioral Disorders. Journal of Neurogenetics 28:1-2, pages 1-4.
Read now

Articles from other publishers (36)

Benjamin R. Helmold, Kate E. Pauss & P. Hande Ozdinler. (2023) TDP-43 protein interactome informs about perturbed canonical pathways and may help develop personalized medicine approaches for patients with TDP-43 pathology. Drug Discovery Today 28:11, pages 103769.
Crossref
Kyle J. Trageser, Eun-Jeong Yang, Chad Smith, Ruth Iban-Arias, Tatsunori Oguchi, Maria Sebastian-Valverde, Umar Haris Iqbal, Henry Wu, Molly Estill, Md Al Rahim, Urdhva Raval, Francis J. Herman, Yong Jie Zhang, Leonard Petrucelli & Giulio Maria Pasinetti. (2023) Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis. Molecular Neurobiology 60:7, pages 4004-4016.
Crossref
Isabell Cordts, Annika Wachinger, Carlo Scialo, Paul Lingor, Magdalini Polymenidou, Emanuele Buratti & Emily Feneberg. (2023) TDP-43 Proteinopathy Specific Biomarker Development. Cells 12:4, pages 597.
Crossref
Klaus Højgaard Jensen, Anna Katharina Stalder, Rasmus Wernersson, Tim-Christoph Roloff-Handschin, Daniel Hvidberg Hansen & Peter M. A. Groenen. (2022) A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules. PLOS ONE 17:5, pages e0268159.
Crossref
Bridget Martinez & PhilipV Peplow. (2022) MicroRNA biomarkers in frontotemporal dementia and to distinguish from Alzheimer’s disease and amyotrophic lateral sclerosis. Neural Regeneration Research 17:7, pages 1412.
Crossref
Bridget Martinez & PhilipV Peplow. (2022) MicroRNA expression in animal models of amyotrophic lateral sclerosis and potential therapeutic approaches. Neural Regeneration Research 17:4, pages 728.
Crossref
Swati Dhasmana, Anupam Dhasmana, Acharan S. Narula, Meena Jaggi, Murali M. Yallapu & Subhash C. Chauhan. (2022) The panoramic view of amyotrophic lateral sclerosis: A fatal intricate neurological disorder. Life Sciences 288, pages 120156.
Crossref
Virgilio Kmetzsch, Vincent Anquetil, Dario Saracino, Daisy Rinaldi, Agnès Camuzat, Thomas Gareau, Ludmila Jornea, Sylvie Forlani, Philippe Couratier, David Wallon, Florence Pasquier, Noémie Robil, Pierre de la Grange, Ivan Moszer, Isabelle Le Ber, Olivier Colliot & Emmanuelle Becker. (2021) Plasma microRNA signature in presymptomatic and symptomatic subjects with C9orf72 -associated frontotemporal dementia and amyotrophic lateral sclerosis . Journal of Neurology, Neurosurgery & Psychiatry 92:5, pages 485-493.
Crossref
Robin Waegaert, Sylvie Dirrig-Grosch, Florian Parisot, Céline Keime, Alexandre Henriques, Jean-Philippe Loeffler & Frédérique René. (2020) Longitudinal transcriptomic analysis of altered pathways in a CHMP2Bintron5-based model of ALS-FTD. Neurobiology of Disease 136, pages 104710.
Crossref
Ying-Tsen Tung, Kuan-Chih Peng, Yen-Chung Chen, Ya-Ping Yen, Mien Chang, Sebastian Thams & Jun-An Chen. (2019) Mir-17∼92 Confers Motor Neuron Subtype Differential Resistance to ALS-Associated Degeneration. Cell Stem Cell 25:2, pages 193-209.e7.
Crossref
Tatyana A. Shelkovnikova, Michail S. Kukharsky, Haiyan An, Pasquale Dimasi, Svetlana Alexeeva, Osman Shabir, Paul R. Heath & Vladimir L. Buchman. (2018) Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis. Molecular Neurodegeneration 13:1.
Crossref
Xiaowei Chen, Zhen Fan, Warren McGee, Mengmeng Chen, Ruirui Kong, Pushuai Wen, Tengfei Xiao, Xiaomin Chen, Jianghong Liu, Li Zhu, Runsheng Chen & Jane Y. Wu. (2017) TDP-43 regulates cancer-associated microRNAs. Protein & Cell 9:10, pages 848-866.
Crossref
Maria Liguori, Nicoletta Nuzziello, Alessandro Introna, Arianna Consiglio, Flavio Licciulli, Eustachio D’Errico, Antonio Scarafino, Eugenio Distaso & Isabella L. Simone. (2018) Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience 11.
Crossref
Kaitlin Weskamp & Sami J. Barmada. (2018) TDP43 and RNA instability in amyotrophic lateral sclerosis. Brain Research 1693, pages 67-74.
Crossref
Babykumari P Chitramuthu, Hugh P J Bennett & Andrew Bateman. (2017) Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease. Brain 140:12, pages 3081-3104.
Crossref
Elvira Valera, Brian Spencer, Jennifer Mott, Margarita Trejo, Anthony Adame, Michael Mante, Edward Rockenstein, Juan C. Troncoso, Thomas G. Beach, Eliezer Masliah & Paula Desplats. (2017) MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Frontiers in Molecular Neuroscience 10.
Crossref
Evgenia Salta & Bart De Strooper. (2017) Noncoding RNAs in neurodegeneration. Nature Reviews Neuroscience 18:10, pages 627-640.
Crossref
Julian Little, Caroline Barakat-Haddad, Rosemary Martino, Tamara Pringsheim, Helen Tremlett, Kyla A. McKay, Pascal van Lieshout, Stephanie J. Walsh, James Gomes & Daniel Krewski. (2017) Genetic variation associated with the occurrence and progression of neurological disorders. NeuroToxicology 61, pages 243-264.
Crossref
Sigrun Lange, Mark Gallagher, Sharad Kholia, Uchini Kosgodage, Mariya Hristova, John Hardy & Jameel Inal. (2017) Peptidylarginine Deiminases—Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?. International Journal of Molecular Sciences 18:6, pages 1196.
Crossref
A.E. Arrant & E.D. Roberson. 2017. The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders. The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders 141 175 .
Alba Jimenez-Pacheco, Jaime M. Franco, Soledad Lopez, Juan Miguel Gomez-Zumaquero, Maria Magdalena Leal-Lasarte, Diana E. Caballero-Hernandez, Marta Cejudo-Guillén & David Pozo. 2017. Neuroepigenomics in Aging and Disease. Neuroepigenomics in Aging and Disease 255 275 .
Christopher S. Krasniak & S. Tariq Ahmad. (2016) The role of CHMP2BIntron5 in autophagy and frontotemporal dementia. Brain Research 1649, pages 151-157.
Crossref
Sarah Morgan & Richard W. Orrell. (2016) Pathogenesis of amyotrophic lateral sclerosis. British Medical Bulletin 119:1, pages 87-98.
Crossref
Chen Eitan & Eran Hornstein. (2016) Vulnerability of microRNA biogenesis in FTD–ALS. Brain Research 1647, pages 105-111.
Crossref
Mónica Zufiría, Francisco Javier Gil-Bea, Roberto Fernández-Torrón, Juan José Poza, Jose Luis Muñoz-Blanco, Ricard Rojas-García, Javier Riancho & Adolfo López de Munain. (2016) ALS: A bucket of genes, environment, metabolism and unknown ingredients. Progress in Neurobiology 142, pages 104-129.
Crossref
Aaron R. Haeusler, Christopher J. Donnelly & Jeffrey D. Rothstein. (2016) The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease. Nature Reviews Neuroscience 17:6, pages 383-395.
Crossref
Simona Rossi, Mauro Cozzolino & Maria Teresa Carrì. (2016) Old versus New Mechanisms in the Pathogenesis of ALS . Brain Pathology 26:2, pages 276-286.
Crossref
Erin C. Hedges, Vera J. Mehler & Agnes L. Nishimura. (2016) The Use of Stem Cells to Model Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: From Basic Research to Regenerative Medicine. Stem Cells International 2016, pages 1-9.
Crossref
Anna Emde, Chen Eitan, Lee‐Loung Liou, Ryan T Libby, Natali Rivkin, Iddo Magen, Irit Reichenstein, Hagar Oppenheim, Raya Eilam, Aurelio Silvestroni, Betty Alajajian, Iddo Z Ben‐Dov, Julianne Aebischer, Alon Savidor, Yishai Levin, Robert Sons, Scott M Hammond, John M Ravits, Thomas Möller & Eran Hornstein. (2015) Dysregulated mi RNA biogenesis downstream of cellular stress and ALS ‐causing mutations: a new mechanism for ALS . The EMBO Journal 34:21, pages 2633-2651.
Crossref
Ximena Paez-Colasante, Claudia Figueroa-Romero, Stacey A. Sakowski, Stephen A. Goutman & Eva L. Feldman. (2015) Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era. Nature Reviews Neurology 11:5, pages 266-279.
Crossref
Emily F. Mendez & Rita Sattler. (2015) Biomarker development for C9orf72 repeat expansion in ALS. Brain Research 1607, pages 26-35.
Crossref
Sami J. Barmada. (2015) Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis. Neurotherapeutics 12:2, pages 340-351.
Crossref
Ilaria Bicchi, Carla Emiliani, Angelo Vescovi & Sabata Martino. (2015) The Big Bluff of Amyotrophic Lateral Sclerosis Diagnosis: The Role of Neurodegenerative Disease Mimics. Neurodegenerative Diseases 15:6, pages 313-321.
Crossref
Christopher J Donnelly, Jonathan C Grima & Rita Sattler. (2014) Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?. Neurodegenerative Disease Management 4:6, pages 417-437.
Crossref
Andrew E Arrant & Erik D Roberson. (2014) MicroRNA-124 modulates social behavior in frontotemporal dementia. Nature Medicine 20:12, pages 1381-1383.
Crossref
Iddo Magen & Eran Hornstein. (2014) Oligonucleotide-based therapy for neurodegenerative diseases. Brain Research 1584, pages 116-128.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.