9
Views
74
CrossRef citations to date
0
Altmetric
Original Article

Neuroendocrine Carcinomas of the Skin: Light Microscopic, Ultrastructural, and Immunohistochemical Analysis

, , &
Pages 499-509 | Published online: 10 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Tomás García-Caballero, Juan Cuevas, Rosalía Gallego, Elena Rosön, Jerönimo Forteza & Andrés Beiras. (1989) Synaptophysinlike Immunoreactivity in the Merkel Cells of Pig-Snout Skin. Ultrastructural Pathology 13:1, pages 55-61.
Read now
Roland Moll, Mary Osborn, Wolfgang Hartschuh, Ingrid Moll, Gustav Mahrle & Klaus Weber. (1986) Variability of Expression and Arrangement of Cytokeratin and Neurofilaments in Cutaneous Neuroendocrine Carcinomas (Merkel Cell Tumors): Immunocytochemical and Biochemical Analysis of Twelve Cases. Ultrastructural Pathology 10:6, pages 473-495.
Read now
Victor E. Gould, Inchul Lee & Samuel P. Hammar. (1985) Neuroendocrine Skin Carcinoma Coexpressing Cytokeratin and Neurofilament Proteins. Ultrastructural Pathology 9:1-2, pages 83-90.
Read now
Janez Lamovec, Vincent A. Memoli, John A. Terzakis, Sheldon C. Sommers & E. Gould. (1984) Pheochromocytoma Producing Immunoreactive ACTH with Cushing's Syndrome. Ultrastructural Pathology 7:1, pages 41-48.
Read now
William R. Green, R. Ilona Linnoila & Timothy J. Triche. (1984) Neuroendocrine Carcinoma of Skin with Simultaneous Cytokeratin Expression. Ultrastructural Pathology 6:2-3, pages 141-152.
Read now
Markku Miettinen, Veli-Pekka Lehto, Ismo Virtanen, Sirpa Asko-Seljavaara, Jaakko Pitkänen & Doris Dahl. (1983) Neuroendocrine Carcinoma of the Skin (Merkel Cell Carcinoma): Ultrastructural and Immunohistochemical Demonstration of Neurofilaments. Ultrastructural Pathology 4:2-3, pages 219-225.
Read now
Daniel J. Santa Cruz & Eugene A. Bauer. (1982) Merkel Cells in the Outer Follicular Sheath. Ultrastructural Pathology 3:1, pages 59-63.
Read now
Gastone Bani. (1982) Ultrastructure of Merkel cells in the epidermis of Hyla arborea . Bollettino di zoologia 49:3-4, pages 257-268.
Read now
Victor E. Gould, Vincent A. Memoli, Loren E. Dardi, Harold J. Sobel, Sheldon C. Somers & Jan V. Johannessen. (1981) Neuroendocrine Carcinomas with Multiple Immunoreactive Peptides and Melanin Production. Ultrastructural Pathology 2:3, pages 199-217.
Read now

Articles from other publishers (63)

Sofia Asioli. 2021. The Spectrum of Neuroendocrine Neoplasia. The Spectrum of Neuroendocrine Neoplasia 335 356 .
Yaohui G. Xu, Juliet L. Aylward, Andrew M. Swanson, Vladimir S. Spiegelman, Erin R. Vanness, Joyce M.C. Teng, Stephen N. Snow & Gary S. Wood. 2020. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 1052 1073.e8 .
B. Llombart, C. Requena & J. Cruz. (2017) Update on Merkel Cell Carcinoma: Epidemiology, Etiopathogenesis, Clinical Features, Diagnosis, and Staging. Actas Dermo-Sifiliográficas (English Edition) 108:2, pages 108-119.
Crossref
B. Llombart, C. Requena & J. Cruz. (2017) Actualización en el carcinoma de células de Merkel: Epidemiología, etiopatogenia, clínica, diagnóstico y estadificación. Actas Dermo-Sifiliográficas 108:2, pages 108-119.
Crossref
Gary S. Wood, Yaohui Gloria Xu, Juliet L. Aylward, Vladimir Spiegelman, Erin Vanness, Joyce M.C. Teng & Stephen N. Snow. 2014. Abeloff's Clinical Oncology. Abeloff's Clinical Oncology 1092 1111.e7 .
Brian Eyden, S. Sankar Banerjee, Yongxin Ru & Paweł LiberskiBrian Eyden & S. Sankar Banerjee. 2013. The Ultrastructure of Human Tumours. The Ultrastructure of Human Tumours 547 641 .
R. Degeorges, C. Reynaud, F. Welby, Z. Belkheyar, A. Abbey-Toby & J.Y. Alnot. (2006) Le carcinome cutané de Merkel : revue de la littérature à propos de deux localisations à la main. Chirurgie de la Main 25:1, pages 22-26.
Crossref
Jean-Marc Thomassin, Arnaud Deveze & Marie-Anne Chrestian. (2006) Systè;me neuroendocrinien disséminé et pathologie cervicofaciale. EMC - Oto-rhino-laryngologie 1:1, pages 1-14.
Crossref
Didier Couillet, Anne Caille †Jean-Claude Guillaume. (2006) Carcinome neuroendocrine cutané primitif. EMC - Dermatologie 1:1, pages 1-8.
Crossref
B Llombart, C Monteagudo, J A Lopez-Guerrero, C Carda, E Jorda, O Sanmartin, S Almenar, I Molina, J M Martin & A Llombart-Bosch. (2005) Clinicopathological and immunohistochemical analysis of 20 cases of Merkel cell carcinoma in search of prognostic markers. Histopathology 46:6, pages 622-634.
Crossref
I. Mikaelian & V. Wong. (2016) Follicular Stem Cell Carcinoma: Histologic, Immunohistochemical, Ultrastructural, and Clinical Characterization in 30 Dogs. Veterinary Pathology 40:4, pages 433-444.
Crossref
Cristina Corzo, Blanca Espinet, Josep Lloreta, Marta Salido, Mar Iglesias, Sergi Serrano & Francesc Solé. (2003) Additional i(1)(q10) in a primitive neuroectodermal tumor type Merkel cell carcinoma as a primary cytogenetic change. Cancer Genetics and Cytogenetics 142:2, pages 165-167.
Crossref
J.M. Thomassin, A. Deveze & M.A. Chrestian. (2002) Sistema neuroendocrino difuso y patología cervicofacial. EMC - Otorrinolaringología 31:4, pages 1-15.
Crossref
Noreen M.G. Walsh. (2001) Primary neuroendocrine (Merkel cell) carcinoma of the skin: Morphologic diversity and implications thereof. Human Pathology 32:7, pages 680-689.
Crossref
Saburo Anzai, Toshihiro Sato, Susumu Takayasu, Yuji Asada, Hiroto Terashi & Syuji Takasaki. (2015) Postoperative Hyponatremia in a Patient with ACTH‐Producing Merkel Cell Carcinoma. The Journal of Dermatology 27:6, pages 397-400.
Crossref
Peiguo Chu & Lawrence Weiss. 2016. Modern Immunohistochemistry. Modern Immunohistochemistry 96 132 .
. 2000. Diagnostic Electron Microscopy. Diagnostic Electron Microscopy 147 216 .
U. Meyer-Pannwitt, K. Kummerfeldt, P. Boubaris & J. Caselitz. (1997) Merkel-Zell-Tumor oder neuroendokrines HautkarzinomMerkel cell carcinoma. Langenbeck's Archives of Surgery 382:6, pages 349-358.
Crossref
M. Härle, N. Arens, I. Moll, W. Back, T. Schulz & H. Scherthan. (2006) Comparative genomic hybridization (CGH) discloses chromosomal and subchromosomal copy number changes in Merkel cell carcinomas. Journal of Cutaneous Pathology 23:5, pages 391-397.
Crossref
MICHAEL L. HAAG, FRANK L. GLASS & NEIL A. FENSKE. (1995) Merkel Cell Carcinoma Diagnosis and Treatment. Dermatologic Surgery 21:8, pages 669-683.
Crossref
Maria P. Foschini & Vincenzo Eusebi. (1995) The spectrum of endocrine tumours of skin. Current Diagnostic Pathology 2:1, pages 2-9.
Crossref
I. Moll, E. Bohnert, C. Herbst, W. Förster, R. Moll & W.W Franke. (1994) Establishment and Characterization of Two Merkel Cell Tumor Cultures. Journal of Investigative Dermatology 102:3, pages 346-353.
Crossref
Jenny Hamilton, Mark R Levine, Richard Lash & Adam Koenigsberg. (1993) Merkel Cell Carcinoma of the Eyelid. Ophthalmic Surgery, Lasers and Imaging Retina 24:11, pages 764-769.
Crossref
Osamu Yamamoto, Akihide Tanimoto, Hiroshi Yasuda, Yoshinori Suenaga & Masakazu Asahi. (2006) A combined occurrence of neuroendocrine carcinoma of the skin and a benign appendageal neoplasm. Journal of Cutaneous Pathology 20:2, pages 173-176.
Crossref
BRIAN D. ZELICKSON & ALVIN S. ZELICKSON. (2007) CURRENT CONCEPTS IN ELECTRON MICROSCOPY. International Journal of Dermatology 32:4, pages 232-242.
Crossref
LAWRENCE L. ANDERSON, TERRI J. PHIPPS & MARTHA L. McCOLLOUGH. (2013) Neuroendocrine Carcinoma of the Skin (Merkel Cell Carcinoma) in a Black. The Journal of Dermatologic Surgery and Oncology 18:5, pages 375-380.
Crossref
Michèle Pitale, Roy B. Sessions & Shaista Husain. (2009) An analysis of prognostic factors in cutaneous neuroendocrine carcinoma. The Laryngoscope 102:3, pages 244-249.
Crossref
A. Kacker, A. Thaker, M. Singh & S. Bahadur. (2007) Primary neuroendocrine carcinoma of the skin arising from the post aural region. The Journal of Laryngology & Otology 106:3, pages 258-260.
Crossref
Tero Kivelä & Ahti Tarkkanen. (1990) The Merkel cell and associated neoplasms in the eyelids and periocular region. Survey of Ophthalmology 35:3, pages 171-187.
Crossref
A. Bergère, A. Lortholary, P. Cornu, C. Richard, G. Bertrand, A. Perrin, A. Delpon & C. Bernaille. (1990) Le carcinome neuroendocrine cutané A propos d'une observation. La Revue de Médecine Interne 11:4, pages 316-318.
Crossref
Nick Mamalis, Rickey D Medlock, John B Holds, Richard L Anderson & Alan S Crandall. (1989) Merkel Cell Tumor of the Eyelid: A Review and Report of an Unusual Case. Ophthalmic Surgery, Lasers and Imaging Retina 20:6, pages 410-414.
Crossref
Roland Chisin, Mark W. Ragozzino, Michael P. Joseph, Alfred L. Weber, Max L. Goodman & Richard L. FabianRoland Chisin, Mark W. Ragozzino, Michael P. Joseph, Alfred L. Weber, Max L. Goodman & Richard L. Fabian. 1989. MRI/CT and Pathology in Head and Neck Tumors. MRI/CT and Pathology in Head and Neck Tumors 11 148 .
I.A. Shah. (1988) Letters to the Case. Pathology - Research and Practice 183:4, pages 508-510.
Crossref
D. Hellner, U. Meyer-Pannwitt, R. Rose, K. Gundlach & H. W. Schreiber. (1988) Klinik und Therapie des MerkelzelltumorsMerkel cell tumor: Clinical feature and therapy. Langenbecks Archiv f�r Chirurgie 373:3, pages 173-181.
Crossref
Mikio Kitazawa, Hisashi Watanabe, Hiroshi Kobayashi, Yoshihisa Ohnishi, Atsuyuki Shitara & Heita Nitto. (2009) MERKEL CELL TUMOR. Pathology International 37:7, pages 1025-1032.
Crossref
A. Rocamora, N. Badía, R. Vives, R. Carrillo, J. Ulloa & A. Ledo. (1987) Epidermotropic primary neuroendocrine (Merkel cell) carcinoma of the skin with Pautrier-like microabscesses. Journal of the American Academy of Dermatology 16:6, pages 1163-1168.
Crossref
L. Layfield, T. Ulich, S. Liao, R. Barr, L. Cheng & K. L. Lewin. (2006) Neuroendocrine carcinoma of the skin: an immunohistochemical study of tumor markers and neuroendocrine products. Journal of Cutaneous Pathology 13:4, pages 268-273.
Crossref
Mitsuya Iafuchi, Hidenobu Watanabe, Noriko Ishihara, Yasuo Takahashi & Mitsumasa Yoshimura. (2009) A NEUROENDOCRINE (MERKEL) CELL CARCINOMA WITH COEXISTING INTRAEPIDERMAL SQUAMOUS CELL CARCINOMA OF THE SKIN. Pathology International 36:7, pages 1099-1108.
Crossref
J. Aneiros Cachaza, R. Garcia Del Moral, J. Loupez Caballero, M. Caracuel Ruiz & T. Caballero Morales. (2008) PRIMARY SMALL CELL CARCINOMA OF SKIN Histogenetical Study. Pathology International 36:6, pages 905-912.
Crossref
Saul Suster, Meyer Ronnen, Eran Lin & Miriam Shewach‐Millet. (2006) Trabecular carcinoma of the skin simulating metastatic disease. Journal of Surgical Oncology 32:2, pages 73-75.
Crossref
LALA M. STAWOWY, EDWARD A. KRULL & KOICH MAEDA. (1986) Merkel Cell Carcinoma: A Challenge. The Journal of Dermatologic Surgery and Oncology 12:5, pages 443-447.
Crossref
M. Drijkoningen, C. De Wolf-Peeters, E. Van Limbergen & V. Desmet. (1986) Merkel cell tumor of the skin: An immunohistochemical study. Human Pathology 17:3, pages 301-307.
Crossref
Yves Merot, Randall J. Margolis, Doris Dahl, Jean-H Saurat & Martin C MihmJrJr. (1986) Coexpression of Neurofilament and Keratin Proteins in Cutaneous Neuroendocrince Carcinoma Cells. Journal of Investigative Dermatology 86:1, pages 74-77.
Crossref
Larry J. Copeland, Karen Cleary, Nour Sneige & Creighton L. Edwards. (1985) Neuroendocrine (Merkel cell) carcinoma of the vulva: A case report and review of the literature. Gynecologic Oncology 22:3, pages 367-378.
Crossref
Timothy K. George, P. Di Anthony Sant'Agnese & John M. Bennett. (1985) Chemotherapy for metastatic merkel cell carcinoma. Cancer 56:5, pages 1034-1038.
Crossref
Emily L. Leff, John S. J. Brooks & John Q. Trojanowski. (1985) Expression of neurofilament and neuron-specific enolase in small cell tumors of skin using immunohistochemistry. Cancer 56:3, pages 625-631.
Crossref
Kenji Matsuo, Akira Sakamoto, Kioko Kawai, HIDEO Tschiyama & Akimi Miyata. (2008) SMALL CELL CARCINOMA OF THE SKIN “NON‐MERKEL CELL TYPE”. Pathology International 35:4, pages 1029-1036.
Crossref
Mark R. Wick, John L. Millns, Richard K. Sibley, Mark R. Pittelkow & Richard K. Winkelmann. (1985) Secondary neuroendocrine carcinomas of the skin. Journal of the American Academy of Dermatology 13:1, pages 134-142.
Crossref
Goos N.P. van Muijen, Dirk J. Ruiter & Sven O. Warnaar. (1985) Intermediate filaments in merkel cell tumors. Human Pathology 16:6, pages 590-595.
Crossref
R. Visser & F. T. Bosman. (2006) Neuroendocrine differentiation in basal cell carcinomas: a retrospective immunohistochemical and ultrastructural study. Journal of Cutaneous Pathology 12:2, pages 117-124.
Crossref
B. Dreno, S. Mousset, J. F. Stalder, B. Bureau, P. Litoux & H. Barrièare. (2006) A study of intermediate filaments (cytokeratin, vimentin, neurofilament) in two cases of Merkel cell tumor. Journal of Cutaneous Pathology 12:1, pages 37-45.
Crossref
G. Bevilacqua, S. Mariotti, M. Castagna, C. Marcocci, G. C. Di Coscio & E. Martino. (2014) Cutaneous metastasis of a radiation-associated thyroid medullary carcinoma. Journal of Endocrinological Investigation 7:6, pages 653-657.
Crossref
Yutaka Yoshida, Takashi Takei, Atsuo Hattori, Tohru Kaku, Kinya Yokokawa & Michio Mori. (2008) MERKEL CELL TUMOR OF THE SKIN Ultrastructural and Immunohistochemical Studies. Pathology International 34:6, pages 1433-1440.
Crossref
Nassif B. N. Ibrahim, James C. Briggs & Catherine M. Corbishley. (1984) Extrapulmonary oat cell carcinoma. Cancer 54:8, pages 1645-1661.
Crossref
D. Katenkamp & V. W�tzig. (1984) Multiple neuroendocrine carcinomas (so-called Merkel cell tumours) of the skin. Virchows Archiv A Pathological Anatomy and Histopathology 404:4, pages 403-411.
Crossref
A. D. Glick, M. A. Holscher & J. D. Crenshaw. (2016) Neuroendocrine Carcinoma of the Skin in a Dog. Veterinary Pathology 20:6, pages 761-763.
Crossref
Thomas F. C. S. Warner, Hideo Uno, G. Reza Hafez, John Burgess, Craig Bolles, Ricardo V. Lloyd & Masamichi Oka. (1983) Merkel cells and merkel cell tumors ultrastructure, immunocytochemistry and review of the literature. Cancer 52:2, pages 238-245.
Crossref
A. Pawlowski & P. J. Lea. (2006) Nevi and melanoma induced by chemical carcinogens in laboratory animals: similarities and differences with human lesions. Journal of Cutaneous Pathology 10:2, pages 81-110.
Crossref
B. FRIGERIO, C. CAPELLA, V. EUSEB, P. TENTI & J. G. AZZOPARDI. (2007) Merkel cell carcinoma of the skin: the structure and origin of normal Merkel cells. Histopathology 7:2, pages 229-249.
Crossref
Ronald A. De LellisHubert J. Wolfe. (2016) Contributions of Immunohistochemistry to Clinical Endocrinology and Endocrine Pathology. Journal of Histochemistry & Cytochemistry 31:1A_suppl, pages 187-192.
Crossref
P.U. Heitz. 1983. Immunocytochemistry. Immunocytochemistry 362 371 .
Rao R. Paladugu, Bharat N. Nathwani, Jordan Goodstein, Loren E. Dardi, Vincent E. Memoli & Victor E. Gould. (1982) Carcinoma of the larynx with mucosubstance production and neuroendocrine differentiation: An ultrastructural and immunohistochemical study. Cancer 49:2, pages 343-349.
Crossref
Loren E. Dardi, Vincent A. Memoli & Victor E. Gould. (2006) Neuroendocrine differentiation in basal cell carcinomas. Journal of Cutaneous Pathology 8:5, pages 335-341.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.