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Research Article

Dissolution evaluation in vitro and bioavailability in vivo of self-microemulsifying drug delivery systems for pH-sensitive drug loratadine

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Pages 175-180 | Received 24 Apr 2014, Accepted 31 Oct 2014, Published online: 21 Nov 2014

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Read on this site (5)

Hongfei Liu, Jiaao Mei, Ying Xu, Lei Tang, Daquan Chen, Yating Zhu, Shuguang Huang, Thomas J Webster & Hui Ding. (2019) Improving The Oral Absorption Of Nintedanib By A Self-Microemulsion Drug Delivery System: Preparation And In Vitro/In Vivo Evaluation. International Journal of Nanomedicine 14, pages 8739-8751.
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Tibor Casian, Sonia Iurian, Catalina Bogdan, Lucia Rus, Mirela Moldovan & Ioan Tomuta. (2017) QbD for pediatric oral lyophilisates development: risk assessment followed by screening and optimization. Drug Development and Industrial Pharmacy 43:12, pages 1932-1944.
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Hitesh Dalvadi, Nikita Patel & Komal Parmar. (2017) Systematic development of design of experiments (DoE) optimised self-microemulsifying drug delivery system of Zotepine. Journal of Microencapsulation 34:3, pages 308-318.
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Mohammed H. Elkomy, Shahira F. El Menshawe, Heba A. Abou-Taleb & Marwa H. Elkarmalawy. (2017) Loratadine bioavailability via buccal transferosomal gel: formulation, statistical optimization, in vitro/in vivo characterization, and pharmacokinetics in human volunteers. Drug Delivery 24:1, pages 781-791.
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Bappaditya Chatterjee, Samah Hamed Almurisi, Ather Ahmed Mahdi Dukhan, Uttam Kumar Mandal & Pinaki Sengupta. (2016) Controversies with self-emulsifying drug delivery system from pharmacokinetic point of view. Drug Delivery 23:9, pages 3639-3652.
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Articles from other publishers (8)

Nayyer Islam, Naveed Ullah Khan, Anam Razzaq, Farid Menaa, Zaheer Ullah Khan, Abid Hussain, Saif Ur Rehman, Haroon Iqbal & Jiang Ni. (2023) Loratadine oral bioavailability enhancement via solid dispersion loaded oro-dispersible films: Formulation, characterization and pharmacokinetics. Colloids and Surfaces B: Biointerfaces 230, pages 113526.
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MOHAMED EL-NABARAWI, DOAA AHMED ELSETOUHY, REHAB ABDELMONEM & AMR EL-HOSSEINI. (2022) ENHANCEMENT OF LORATADINE DISSOLUTION BY SURFACE SOLID DISPERSION: THE POTENTIAL USE OF CO-PROCESSED EXCIPIENTS AS ON-SURFACE CARRIERS. International Journal of Applied Pharmaceutics, pages 202-214.
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Sonia Iurian, Cătălina Bogdan, Ștefana Suciu, Dana-Maria Muntean, Lucia Rus, Mihaela Berindeie, Szidonia Bodi, Rita Ambrus & Ioan Tomuță. (2022) Milk Oral Lyophilizates with Loratadine: Screening for New Excipients for Pediatric Use. Pharmaceutics 14:7, pages 1342.
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Dandan Yang, Ruirui Li, Fang Zhang, Li Qin, Feifei Peng, Shanshan Jiang, Huiyang He, Xiumei Lu & Peng Zhang. (2019) A simple and low-energy method to prepare loratadine nanosuspensions for oral bioavailability improvement: preparation, characterization, and in vivo evaluation. Drug Delivery and Translational Research 10:1, pages 192-201.
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Rita Ambrus, Areen Alshweiat, Ildikó Csóka, George Ovari, Ammar Esmail & Norbert Radacsi. (2019) 3D-printed electrospinning setup for the preparation of loratadine nanofibers with enhanced physicochemical properties. International Journal of Pharmaceutics 567, pages 118455.
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Areen Alshweiat, Gábor Katona, Ildikó Csóka & Rita Ambrus. (2018) Design and characterization of loratadine nanosuspension prepared by ultrasonic-assisted precipitation. European Journal of Pharmaceutical Sciences 122, pages 94-104.
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Jesus Rafael Rodriguez Amado, Ariadna Lafourcade Prada, Jonatas Lobato Duarte, Hady Keita, Heitor Rivero da Silva, Adriana Maciel Ferreira, Edgar Hernandez Sosa & Jose Carlos Tavares Carvalho. (2017) Development, stability and in vitro delivery profile of new loratadine-loaded nanoparticles. Saudi Pharmaceutical Journal 25:8, pages 1158-1168.
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Shenwu Zhang, Mengchi Sun, Yongshan Zhao, Xuyang Song, Zhonggui He, Jian Wang & Jin Sun. (2017) Molecular mechanism of polymer-assisting supersaturation of poorly water-soluble loratadine based on experimental observations and molecular dynamic simulations. Drug Delivery and Translational Research 7:5, pages 738-749.
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