Advanced search
Publication Cover
Journal of Microencapsulation
Micro and Nano Carriers
Volume 32, 2015 - Issue 8
Submit an article Journal homepage
409
Views
29
CrossRef citations to date
0
Altmetric
Research Article

Development of chitosan–pullulan composite nanoparticles for nasal delivery of vaccines: optimisation and cellular studies

Erdal CevherDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey, Correspondence[email protected]
,
Stefan K. SalomonDepartment of Pharmaceutics, The UCL School of Pharmacy, University of London, London, UK, ;GlaxoSmithKline, London, UK,
,
Apostolos MakrakisDepartment of Pharmaceutics, The UCL School of Pharmacy, University of London, London, UK,
,
Xiong Wei LiDepartment of Pharmaceutics, The UCL School of Pharmacy, University of London, London, UK, ;PsiOxus Therapeutics Ltd., Abingdon, Oxfordshire, UK, and
,
Steve BrocchiniDepartment of Pharmaceutics, The UCL School of Pharmacy, University of London, London, UK,
&
H. Oya AlparDepartment of Pharmaceutics, The UCL School of Pharmacy, University of London, London, UK, ;Department of Pharmaceutics, Faculty of Pharmacy, Kemerburgaz University, Istanbul, Turkey
Pages 755-768 | Received 21 Jun 2015, Accepted 10 Jul 2015, Published online: 31 Aug 2015

Citations (29)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Dong Shik Kim, Jung Hyun Cho, Jong Hyuck Park, Jung Suk Kim, Eon Soo Song, Jaewook Kwon, Bhupendra Raj Giri, Sung Giu Jin, Kyeong Soo Kim, Han-Gon Choi & Dong Wuk Kim. (2019) Self-microemulsifying drug delivery system (SMEDDS) for improved oral delivery and photostability of methotrexate. International Journal of Nanomedicine 14, pages 4949-4960.
Read now
Tingting Chen, Shunying Li, Wenting Zhu, Zhi Liang & Qingbing Zeng. (2019) Self-assembly pH-sensitive chitosan/alginate coated polyelectrolyte complexes for oral delivery of insulin. Journal of Microencapsulation 36:1, pages 96-107.
Read now
Liliana Aranha Caetano, Lara Figueiredo, António J. Almeida & L. M. D. Gonçalves. (2017) BCG-loaded chitosan microparticles: interaction with macrophages and preliminary in vivo studies. Journal of Microencapsulation 34:2, pages 203-217.
Read now
Ida Genta, Claudia Colonna, Bice Conti, Paolo Caliceti, Stefano Salmaso, Pietro Speziale, Giampiero Pietrocola, Enrica Chiesa, Tiziana Modena & Rossella Dorati. (2016) CNA-loaded PLGA nanoparticles improve humoral response againstS. aureus-mediated infections in a mouse model: subcutaneous vs. nasal administration strategy. Journal of Microencapsulation 33:8, pages 750-762.
Read now

Articles from other publishers (25)

Laura Maria Duran Gleriani Primo, Cesar Augusto Roque-Borda, Christian Shleider Carnero Canales, Icaro Putinhon Caruso, Isabella Ottenio de Lourenço, Vitória Maria Medalha Colturato, Rafael Miguel Sábio, Fernando Alves de Melo, Eduardo Festozo Vicente, Marlus Chorilli, Hernane da Silva Barud, Paula Aboud Barbugli, Henrik Franzyk, Paul Robert Hansen & Fernando Rogério Pavan. (2024) Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis. Carbohydrate Polymers 323, pages 121449.
Crossref
Eman FS. Taha, Noha Sayed Hamed & Sahar Khateeb. (2023) Etoricoxib nanostructured lipid carriers attenuate inflammation by modulating Cyclooxygenase-2 signaling and activation of nuclear factor-κB-p65 pathways in radiation-induced acute cardiotoxicity in rats. European Journal of Pharmacology 957, pages 176029.
Crossref
Mónica María Cruz-Santos, Felipe Antônio Fernandes Antunes, Gabriel Leda Arruda, Vinicius Pereira Shibukawa, Carina Aline Prado, Nayeli Ortiz-Silos, María José Castro-Alonso, Paulo Ricardo Franco Marcelino & Júlio César Santos. (2023) Production and applications of pullulan from lignocellulosic biomass: Challenges and perspectives. Bioresource Technology 385, pages 129460.
Crossref
Melike Sessevmez, Genada Sinani, Alper Okyar, H. Oya Alpar & Erdal Cevher. (2023) Induction of humoral and cell-mediated immunity in mice by chitosan-curdlan composite nanoparticles administered intranasally and subcutaneously. Journal of Drug Delivery Science and Technology 86, pages 104704.
Crossref
Muhammet Davut Arpa, Neslihan Üstündağ Okur, Mehmet Koray Gök, Saadet Özgümüş & Erdal Cevher. (2023) Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine. International Journal of Pharmaceutics 642, pages 123168.
Crossref
Qiulin Wang, Xiaoyu Wang & Yakai Feng. (2023) Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications. Gels 9:5, pages 373.
Crossref
Hale Alvandi, Ashrafalsadat Hatamian-Zarmi & Thomas J. Webster. 2023. Nanomedicine. Nanomedicine 415 452 .
Uday Chintapula, Tanmayee Chikate, Deepsundar Sahoo, Amie Kieu, Ingrid D. Guerrero Rodriguez, Kytai T. Nguyen & Daniel Trott. (2022) Immunomodulation in age‐related disorders and nanotechnology interventions. WIREs Nanomedicine and Nanobiotechnology 15:1.
Crossref
Ramón Román‐Doval, Alejandro Gómez‐Sánchez, Elmer Joel Millán‐Casarrubias, Evgen Prokhorov, Fernando Montejo‐Alvaro, Andres de Luna Bugallo, Montserrat Hernández‐Iturriaga, Marla Leal‐Cervantes, Gabriel Luna‐Barcenas & Sandra Mendoza. (2022) Physicochemical properties of pullulan/chitosan/graphene oxide composite films. Polymer International 71:8, pages 959-965.
Crossref
Mahendra Rai, Magdalena Wypij, Avinash P. Ingle, Joanna Trzcińska-Wencel & Patrycja Golińska. (2021) Emerging Trends in Pullulan-Based Antimicrobial Systems for Various Applications. International Journal of Molecular Sciences 22:24, pages 13596.
Crossref
Alexander Plucinski, Zan Lyu & Bernhard V. K. J. Schmidt. (2021) Polysaccharide nanoparticles: from fabrication to applications. Journal of Materials Chemistry B 9:35, pages 7030-7062.
Crossref
Francesca Motta, M. Eric Gershwin & Carlo Selmi. (2021) Mushrooms and immunity. Journal of Autoimmunity 117, pages 102576.
Crossref
Ayse Sumeyye Akay, Volkan Arısan, Erdal Cevher, Melike Sessevmez & Betul Cam. (2020) Oxytocin‐loaded sustained‐release hydrogel graft provides accelerated bone formation: An experimental rat study. Journal of Orthopaedic Research 38:8, pages 1676-1687.
Crossref
Vaclav Vetvicka, Luca Vannucci & Petr Sima. (2019) β‐glucan as a new tool in vaccine development. Scandinavian Journal of Immunology 91:2.
Crossref
Genada Sinani, Melike Sessevmez, M. Koray Gök, Saadet Özgümüş, H. Oya Alpar & Erdal Cevher. (2019) Modified chitosan-based nanoadjuvants enhance immunogenicity of protein antigens after mucosal vaccination. International Journal of Pharmaceutics 569, pages 118592.
Crossref
Mahmood Alizadeh-Sani, Ali Ehsani, Ehsan Moghaddas Kia & Arezou Khezerlou. (2019) Microbial gums: introducing a novel functional component of edible coatings and packaging. Applied Microbiology and Biotechnology 103:17, pages 6853-6866.
Crossref
Tatiana A. Korolenko, Nataliya P. Bgatova & Vaclav Vetvicka. (2019) Glucan and Mannan—Two Peas in a Pod. International Journal of Molecular Sciences 20:13, pages 3189.
Crossref
Aysegul ERTEN TAYSI, Erdal CEVHER, Melike SESSEVMEZ, Vakur OLGAC, Nuri MERT TAYSI & Berkem ATALAY. (2019) The efficacy of sustained-release chitosan microspheres containing recombinant human parathyroid hormone on MRONJ. Brazilian Oral Research 33.
Crossref
Bor Shin Chee & Michael Nugent. 2019. Natural Polysaccharides in Drug Delivery and Biomedical Applications. Natural Polysaccharides in Drug Delivery and Biomedical Applications 589 615 .
Wahid Khan, Ester Abtew, Sheela Modani & Abraham J. Domb. (2018) Polysaccharide Based Nanoparticles. Israel Journal of Chemistry 58:12, pages 1315-1329.
Crossref
Santiswarup Singha, Kun Shao, Kristofor K. Ellestad, Yang Yang & Pere Santamaria. (2018) Nanoparticles for Immune Stimulation Against Infection, Cancer, and Autoimmunity. ACS Nano 12:11, pages 10621-10635.
Crossref
Sara Salatin & Ahmad Yari Khosroushahi. (2017) Overviews on the cellular uptake mechanism of polysaccharide colloidal nanoparticles. Journal of Cellular and Molecular Medicine 21:9, pages 1668-1686.
Crossref
Genada Sinani, Melike Sessevmez, M. Koray Gök, Saadet Özgümüş, Alper Okyar, H. Oya Alpar & Erdal Cevher. (2017) Nasal vaccination with poly(β-amino ester)-poly( d , l -lactide- co -glycolide) hybrid nanoparticles. International Journal of Pharmaceutics 529:1-2, pages 1-14.
Crossref
Olga Kammona, Vassilis Bourganis, Theodora Karamanidou & Costas Kiparissides. (2017) Recent developments in nanocarrier-aided mucosal vaccination. Nanomedicine 12:9, pages 1057-1074.
Crossref
Sabyasachi Maiti & Sougata Jana. 2017. Particulate Technology for Delivery of Therapeutics. Particulate Technology for Delivery of Therapeutics 227 251 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.