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Research Article

Optimization of novel pentablock copolymer based composite formulation for sustained delivery of peptide/protein in the treatment of ocular diseases

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Pages 103-113 | Received 02 Nov 2014, Accepted 09 Nov 2015, Published online: 11 Mar 2016

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Read on this site (4)

Zinah K. Al-Qaysi, Ian G. Beadham, Sianne L. Schwikkard, Joseph C. Bear, Ali A. Al-Kinani & Raid G. Alany. (2023) Sustained release ocular drug delivery systems for glaucoma therapy. Expert Opinion on Drug Delivery 20:7, pages 905-919.
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Mingliang Fan, Yue Huang, Xinlin Zhu, Jiayu Zheng & Mingwei Du. (2023) Octreotide and Octreotide-derived delivery systems. Journal of Drug Targeting 31:6, pages 569-584.
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Rohit Bisht, Sonali Nirmal, Rupesh Agrawal, Gaurav K. Jain & Jayabalan Nirmal. (2021) Injectable in-situ gel depot system for targeted delivery of biologics to the retina. Journal of Drug Targeting 29:1, pages 46-59.
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Vibhuti Agrahari, Vivek Agrahari, Abhirup Mandal, Dhananjay Pal & Ashim K. Mitra. (2017) How are we improving the delivery to back of the eye? Advances and challenges of novel therapeutic approaches. Expert Opinion on Drug Delivery 14:10, pages 1145-1162.
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Articles from other publishers (17)

Divyesh H. Shastri, Ana Catarina Silva & Hugo Almeida. (2023) Ocular Delivery of Therapeutic Proteins: A Review. Pharmaceutics 15:1, pages 205.
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Maitri Bhatt & Pravin Shende. (2021) Modulated approaches for strategic transportation of proteins and peptides via ocular route. Journal of Drug Delivery Science and Technology 66, pages 102835.
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Sunil Kumar Dubey, Rajesh Pradhan, Siddhanth Hejmady, Gautam Singhvi, Hira Choudhury, Bapi Gorain & Prashant Kesharwani. (2021) Emerging innovations in nano-enabled therapy against age-related macular degeneration: A paradigm shift. International Journal of Pharmaceutics 600, pages 120499.
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Zih‐Cheng Su, Shih‐Jie Lin, Yu‐Hsuan Chang, Wen‐Ling Yeh & I‐Ming Chu. (2020) Synthesis, characterization, and cytotoxicity of PCL–PEG–PCL diacrylate and agarose interpenetrating network hydrogels for cartilage tissue engineering . Journal of Applied Polymer Science 137:45, pages 49409.
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Francesco Baino & Saeid Kargozar. (2020) Regulation of the Ocular Cell/Tissue Response by Implantable Biomaterials and Drug Delivery Systems. Bioengineering 7:3, pages 65.
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Vrinda Gote, Sadia Sikder, Jeff Sicotte & Dhananjay Pal. (2019) Ocular Drug Delivery: Present Innovations and Future Challenges. Journal of Pharmacology and Experimental Therapeutics 370:3, pages 602-624.
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Pratikkumar Patel, Abhirup Mandal, Vrinda Gote, Dhananjay Pal & Ashim K. Mitra. (2019) Thermosensitive hydrogel-based drug delivery system for sustained drug release. Journal of Polymer Research 26:6.
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Mary Joseph Ngatuni, Hoang M. Trinh, Dhananjay Pal & Ashim K. Mitra. (2018) Novel Random Triblock Copolymers for Sustained Delivery of Macromolecules for the Treatment of Ocular Diseases. AAPS PharmSciTech 19:8, pages 3871-3885.
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Alex Oselu Owiti, Dhananjay Pal & Ashim Mitra. (2018) PSMA Antibody-Conjugated Pentablock Copolymer Nanomicellar Formulation for Targeted Delivery to Prostate Cancer. AAPS PharmSciTech 19:8, pages 3534-3549.
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Alex Oselu Owiti, Ashim Mitra, Mary Joseph & Dhananjay Pal. (2018) Strategic Pentablock Copolymer Nanomicellar Formulation for Paclitaxel Delivery System. AAPS PharmSciTech 19:7, pages 3110-3122.
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Julieta C. Imperiale, Gabriela B. Acosta & Alejandro Sosnik. (2018) Polymer-based carriers for ophthalmic drug delivery. Journal of Controlled Release 285, pages 106-141.
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Vibhuti Agrahari & Vivek Agrahari. (2018) Advances and applications of block-copolymer-based nanoformulations. Drug Discovery Today 23:5, pages 1139-1151.
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Vibhuti Agrahari, Sulabh P. Patel, Nikhil Dhall, Zach Aulgur, Siddhant Thukral, Xiaoyan Yang, Ryan Conley & Ashim K. Mitra. (2017) Nanoparticles in thermosensitive gel based composite nanosystem for ocular diseases. Drug Delivery and Translational Research 8:2, pages 422-435.
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Abhirup Mandal, Dhananjay Pal, Vibhuti Agrahari, Hoang My Trinh, Mary Joseph & Ashim K. Mitra. (2018) Ocular delivery of proteins and peptides: Challenges and novel formulation approaches. Advanced Drug Delivery Reviews 126, pages 67-95.
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Yao Li, Yunli Zhou, Wenli Han, Mingxin Shi, Hua Zhao, Yuying Liu, Fengmei Zhang & Jingqing Zhang. (2017) Novel lipidic and bienzymatic nanosomes for efficient delivery and enhanced bioactivity of catalase. International Journal of Pharmaceutics 532:1, pages 157-165.
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Vibhuti Agrahari, Guorong Li, Vivek Agrahari, Iris Navarro, Kristin Perkumas, Abhirup Mandal, W Daniel Stamer & Ashim K Mitra. (2017) Pentablock copolymer dexamethasone nanoformulations elevate MYOC: in vitro liberation, activity and safety in human trabecular meshwork cells . Nanomedicine 12:16, pages 1911-1926.
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Mitra Alami-Milani, Parvin Zakeri-Milani, Hadi Valizadeh, Roya Salehi, Sara Salatin, Ali Naderinia & Mitra Jelvehgari. (2017) Novel Pentablock Copolymers as Thermosensitive Self-Assembling Micelles for Ocular Drug Delivery. Advanced Pharmaceutical Bulletin 7:1, pages 11-20.
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