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Paroxysmal sympathetic hyperactivity after acquired brain injury: A review of diagnostic criteria

, B MedSc, B Med, , B Med, &
Pages 925-932 | Received 05 Jan 2011, Accepted 01 May 2011, Published online: 03 Aug 2011

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L.D. Wilson, T.C. Leath & M.B. Patel. 2017. New Therapeutics for Traumatic Brain Injury. New Therapeutics for Traumatic Brain Injury 145 158 .
Parmod Kumar Bithal & Keshav Goyal. 2017. Challenging Topics in Neuroanesthesia and Neurocritical Care. Challenging Topics in Neuroanesthesia and Neurocritical Care 69 81 .
Zuxing Gu, Hong Song, Yu Jiang, Jeonghone Choi, Hongjiang He, Lui Sha & Ming Gu. (2016) An integrated Medical CPS for early detection of paroxysmal sympathetic hyperactivity. An integrated Medical CPS for early detection of paroxysmal sympathetic hyperactivity.
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Crossref
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Crossref
A. K. Godbolt, M. Stenberg, J. Jakobsson, K. Sorjonen, K. Krakau, B.-M. Stalnacke & C. Nygren DeBoussard. (2015) Subacute complications during recovery from severe traumatic brain injury: frequency and associations with outcome. BMJ Open 5:4, pages e007208-e007208.
Crossref
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Crossref
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Crossref
Courtney Takahashi, Holly E. Hinson & Ian J. Baguley. 2015. Traumatic Brain Injury, Part II. Traumatic Brain Injury, Part II 539 551 .
Samson Sujit Kumar Gaddam, Thomas Buell & Claudia S. Robertson. 2015. Traumatic Brain Injury, Part I. Traumatic Brain Injury, Part I 205 218 .
Devon Lump & Megan Moyer. (2014) Paroxysmal Sympathetic Hyperactivity after Severe Brain Injury. Current Neurology and Neuroscience Reports 14:11.
Crossref
Ian J. BaguleyIain E. PerkesJuan-Francisco Fernandez-OrtegaAlejandro A. RabinsteinGiuliano DolceHenk T. Hendricks. (2014) Paroxysmal Sympathetic Hyperactivity after Acquired Brain Injury: Consensus on Conceptual Definition, Nomenclature, and Diagnostic Criteria. Journal of Neurotrauma 31:17, pages 1515-1520.
Crossref
Daniel Agustín Godoy, Gustavo Rene Piñero & Luca Masotti. (2014) Paroxysmal sympathetic hyperactivity, traumatic brain injury, and β-blockers. Journal of Trauma and Acute Care Surgery 77:2, pages 387.
Crossref
Joshua D. Hughes & Alejandro A. Rabinstein. (2013) Early Diagnosis of Paroxysmal Sympathetic Hyperactivity in the ICU. Neurocritical Care 20:3, pages 454-459.
Crossref
Billy Gao, Jeffrey A. Pollock & Holly E. Hinson. (2014) Paroxysmal sympathetic hyperactivity in hemispheric intraparenchymal hemorrhage. Annals of Clinical and Translational Neurology 1:3, pages 215-219.
Crossref
Yasusei Okada, Hiroshi Inagawa, Naoki Kojima, Kazumasa Yamaguchi & Nobuo Sasaki. (2014) Two cases of paroxysmal sympathetic hyperactivity following head injury. Journal of the Japanese Society of Intensive Care Medicine 21:3, pages 268-272.
Crossref
Yasuhiro Kuroda. (2014) Pitfalls of targeted temperature management in neurocritical care: paroxysmal sympathetic hyperactivity. Journal of the Japanese Society of Intensive Care Medicine 21:3, pages 230-233.
Crossref
H. Alex Choi, Sang-Beom Jeon, Sophie Samuel, Teresa Allison & Kiwon Lee. (2013) Paroxysmal Sympathetic Hyperactivity After Acute Brain Injury. Current Neurology and Neuroscience Reports 13:8.
Crossref
M.J. Kenney & L.J. Mosher. (2013) Translational physiology and SND recordings in humans and rats: A glimpse of the recent past with an eye on the future. Autonomic Neuroscience 176:1-2, pages 5-10.
Crossref
KATHERINE A KIRK, MICHAEL SHOYKHET, JONG H JEONG, ELIZABETH C TYLER‐KABARA, MARYANNE J HENDERSON, MICHAEL J BELL & ERICKA L FINK. (2012) Dysautonomia after pediatric brain injury. Developmental Medicine & Child Neurology 54:8, pages 759-764.
Crossref
Holly E. Hinson & Kevin N. Sheth. (2012) Manifestations of the hyperadrenergic state after acute brain injury. Current Opinion in Critical Care 18:2, pages 139-145.
Crossref

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