2,862
Views
64
CrossRef citations to date
0
Altmetric
Reviews

Randomized controlled trials in adult traumatic brain injury

, , , &
Pages 1523-1548 | Received 23 Dec 2011, Accepted 26 Jul 2012, Published online: 19 Nov 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Sonya Kim, Marianne Mortera, Patricia C. Heyn, Pallavi Sood, Pey-Shan Wen, Diana Chen Wong, Sarah Tanveer & Xiaolei Hu. (2022) An overview of systematic reviews on the pharmacological randomized controlled trials for reducing intracranial pressure after traumatic brain injury. Brain Injury 36:7, pages 829-840.
Read now
Alison D. Cox, Madeline Pontone & Karl F. Gunnarsson. (2022) Program evaluation of in-patient treatment units for adults with acquired brain injury and challenging behavior. Brain Injury 36:3, pages 321-331.
Read now
Sonya Kim, Marianne Mortera, Xiaolei Hu, Shilpa Krishnan, Lilian Hoffecker, Amy Herrold, Lauren Terhorst, Laurie King, Joseph Machtinger, Jennifer M. Zumsteg, Ahmed Negm & Patricia Heyn. (2019) Overview of pharmacological interventions after traumatic brain injuries: impact on selected outcomes. Brain Injury 33:4, pages 442-455.
Read now
Irene Paterniti, Marika Cordaro, Michele Navarra, Emanuela Esposito & Salvatore Cuzzocrea. (2015) Emerging pharmacotherapy for treatment of traumatic brain injury: targeting hypopituitarism and inflammation . Expert Opinion on Emerging Drugs 20:4, pages 583-596.
Read now
Ye Xiong, Yanlu Zhang, Asim Mahmood & Michael Chopp. (2015) Investigational agents for treatment of traumatic brain injury. Expert Opinion on Investigational Drugs 24:6, pages 743-760.
Read now
Marianne Sivertsen & Britt Normann. (2015) Embodiment and self in reorientation to everyday life following severe traumatic brain injury. Physiotherapy Theory and Practice 31:3, pages 153-159.
Read now
Christine Curran, Diana Dorstyn, Con Polychronis & Linley Denson. (2015) Functional outcomes of community-based brain injury rehabilitation clients. Brain Injury 29:1, pages 25-32.
Read now
Christopher Tolleson & Oscar Guillamondegui. (2014) The success of traumatic brain injury registry outreach. Brain Injury 28:3, pages 286-291.
Read now

Articles from other publishers (56)

Daniel T. Laskowitz & David W. Van Wyck. (2023) ApoE Mimetic Peptides as Therapy for Traumatic Brain Injury. Neurotherapeutics 20:6, pages 1496-1507.
Crossref
Lucia M. Li, Alan Carson & Kristen Dams-O’Connor. (2023) Psychiatric sequelae of traumatic brain injury — future directions in research. Nature Reviews Neurology 19:9, pages 556-571.
Crossref
Emily L. Morrow, Melissa C. Duff & Lindsay S. Mayberry. (2022) Mediators, Moderators, and Covariates: Matching Analysis Approach for Improved Precision in Cognitive-Communication Rehabilitation Research. Journal of Speech, Language, and Hearing Research 65:11, pages 4159-4171.
Crossref
Christopher M. Olsen, Amy A. Herrold, Alana C. Conti & Cole Vonder Haar. (2022) Editorial: Behavioral outcomes of traumatic brain injury. Frontiers in Behavioral Neuroscience 16.
Crossref
Cydni N. Williams, Cindy T. McEvoy, Miranda M. Lim, Steven A. Shea, Vivek Kumar, Divya Nagarajan, Kurt Drury, Natalia Rich-Wimmer & Trevor A. Hall. (2022) Sleep and Executive Functioning in Pediatric Traumatic Brain Injury Survivors after Critical Care. Children 9:5, pages 748.
Crossref
Paolo de Angelis, Elinore J. Kaufman, Philip S. Barie, Nicole E. Leahy, Robert J. Winchell & Mayur Narayan. (2022) Disparities in Insurance Status Are Associated With Outcomes but Not Timing of Trauma Care. Journal of Surgical Research 273, pages 233-246.
Crossref
Melissa C. Duff, Emily L. Morrow, Malcolm Edwards, Ryan McCurdy, Sharice Clough, Nirav Patel, Kimberly Walsh & Natalie V. Covington. (2022) The Value of Patient Registries to Advance Basic and Translational Research in the Area of Traumatic Brain Injury. Frontiers in Behavioral Neuroscience 16.
Crossref
Dae Han Choi, Tae Seok Jeong & Woo Kyung Kim. (2022) Clinical Outcome of Patients Diagnosed Traumatic Intracranial Epidural Hematoma With Severe Brain Injury (Glasgow Coma Scale ≤8) Who Undergo Surgery: A Report From the Korean Neuro-Trauma Data Bank System. Korean Journal of Neurotrauma 18:2, pages 153.
Crossref
Bar Lambez & Eli Vakil. (2021) The effectiveness of memory remediation strategies after traumatic brain injury: Systematic review and meta-analysis. Annals of Physical and Rehabilitation Medicine 64:5, pages 101530.
Crossref
Michael KarlssonZhihui YangSanjeev ChawlaNile DelsoBryan PukenasEskil ElmérMatilda HugerthSusan S. MarguliesJohannes EhingerMagnus J. HanssonKevin K.W. WangTodd J. Kilbaugh. (2021) Evaluation of Diffusion Tensor Imaging and Fluid Based Biomarkers in a Large Animal Trial of Cyclosporine in Focal Traumatic Brain Injury. Journal of Neurotrauma 38:13, pages 1870-1878.
Crossref
Daniel Kwasi Ahorsu, Emma Sethina Adjaottor & Bess Yin Hung Lam. (2021) Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Brain Sciences 11:7, pages 840.
Crossref
Natalie V. Covington & Melissa C. Duff. (2021) Heterogeneity Is a Hallmark of Traumatic Brain Injury, Not a Limitation: A New Perspective on Study Design in Rehabilitation Research. American Journal of Speech-Language Pathology 30:2S, pages 974-985.
Crossref
N.M. Weston, A.T. Rolfe, A.H. Freelin, T.M. Reeves & D. Sun. (2021) Traumatic brain injury modifies synaptic plasticity in newly-generated granule cells of the adult hippocampus. Experimental Neurology 336, pages 113527.
Crossref
Shoumitro Deb, Lina Aimola, Verity Leeson, Mayur Bodani, Lucia Li, Tim Weaver, David Sharp, Paul Bassett & Mike Crawford. (2020) Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial. BMJ Open 10:9, pages e036300.
Crossref
Takao Yasuhara, Satoshi Kawauchi, Kyohei Kin, Jun Morimoto, Masahiro Kameda, Tatsuya Sasaki, Brooke Bonsack, Chase Kingsbury, Naoki Tajiri, Cesario V. Borlongan & Isao Date. (2019) Cell therapy for central nervous system disorders: Current obstacles to progress. CNS Neuroscience & Therapeutics 26:6, pages 595-602.
Crossref
David J. Peeler, Nicholas Luera, Philip J. Horner, Suzie H. Pun & Drew L. Sellers. (2020) Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury. Journal of Controlled Release 322, pages 149-156.
Crossref
José Luís Alves, Joana Rato & Vitor Silva. (2019) Why Does Brain Trauma Research Fail?. World Neurosurgery 130, pages 115-121.
Crossref
Norhamizan Hamzah, Vairavan Narayanan, Norlisah Ramli, Nor Atikah Mustapha, Nor Adibah Mohammad Tahir, Li Kuo Tan, Mahmoud Danaee, Nor Asiah Muhamad, Avril Drummond, Roshan das Nair, Sing Yau Goh & Mazlina Mazlan. (2019) Randomised controlled clinical trial of a structured cognitive rehabilitation in patients with attention deficit following mild traumatic brain injury: study protocol. BMJ Open 9:9, pages e028711.
Crossref
Anelia A. Y. Kassi, Anil K. Mahavadi, Angelica Clavijo, Daniela Caliz, Stephanie W. Lee, Aminul I. Ahmed, Shoji Yokobori, Zhen Hu, Markus S. Spurlock, Joseph M Wasserman, Karla N. Rivera, Samuel Nodal, Henry R. Powell, Long Di, Rolando Torres, Lai Yee Leung, Andres Mariano Rubiano, Ross M. Bullock & Shyam Gajavelli. (2019) Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI. Frontiers in Neurology 9.
Crossref
Yanlu Zhang, Michael Chopp, Zheng Gang Zhang, Yi Zhang, Li Zhang, Mei Lu, Talan Zhang, Stefan Winter, Edith Doppler, Hemma Brandstäetter, Asim Mahmood & Ye Xiong. (2018) Cerebrolysin Reduces Astrogliosis and Axonal Injury and Enhances Neurogenesis in Rats After Closed Head Injury. Neurorehabilitation and Neural Repair 33:1, pages 15-26.
Crossref
Yanlu ZhangMichael Chopp, Zheng Gang Zhang, Yi Zhang, Li Zhang, Mei LuTalan ZhangStefan Winter, Hemma Brandstätter, Asim MahmoodYe Xiong. (2018) Prospective, randomized, blinded, and placebo-controlled study of Cerebrolysin dose-response effects on long-term functional outcomes in a rat model of mild traumatic brain injury. Journal of Neurosurgery 129:5, pages 1295-1304.
Crossref
Tara M. BrinkmanKirsten K. NessZhenghong LiI-Chan HuangKevin R. KrullAmar GajjarThomas E. MerchantJames L. KloskyRobyn E. PartinIngrid Tonning OlssonFrederick BoopPaul KlimoJrJrWassim ChemaitillyRaja B. KhanDeokumar SrivastavaLeslie L. RobisonMelissa M. HudsonGregory T. Armstrong. (2018) Attainment of Functional and Social Independence in Adult Survivors of Pediatric CNS Tumors: A Report From the St Jude Lifetime Cohort Study. Journal of Clinical Oncology 36:27, pages 2762-2769.
Crossref
Katie A. Ragsdale, Michael A. Gramlich, Deborah C. Beidel, Sandra M. Neer, Emily G. Kitsmiller & Krystal I. Morrison. (2018) Does Traumatic Brain Injury Attenuate the Exposure Therapy Process?. Behavior Therapy 49:4, pages 617-630.
Crossref
Anneliese Synnot, Peter Bragge, Carole Lunny, David Menon, Ornella Clavisi, Loyal Pattuwage, Victor Volovici, Stefania Mondello, Maryse C. Cnossen, Emma Donoghue, Russell L. Gruen & Andrew Maas. (2018) The currency, completeness and quality of systematic reviews of acute management of moderate to severe traumatic brain injury: A comprehensive evidence map. PLOS ONE 13:6, pages e0198676.
Crossref
Bhanu Sharma, David W. Lawrence & Michael G. Hutchison. (2018) Branched Chain Amino Acids (BCAAs) and Traumatic Brain Injury: A Systematic Review. Journal of Head Trauma Rehabilitation 33:1, pages 33-45.
Crossref
Juan Lu & Mirinda Gormley. 2018. Pre-Clinical and Clinical Methods in Brain Trauma Research. Pre-Clinical and Clinical Methods in Brain Trauma Research 361 378 .
Per-Olof Grände. (2017) Critical Evaluation of the Lund Concept for Treatment of Severe Traumatic Head Injury, 25 Years after Its Introduction. Frontiers in Neurology 8.
Crossref
Cara Meixner, Cynthia R. O’Donoghue & Vesna Hart. (2017) Impact of the Brain Injury Family Intervention (BIFI) training on rehabilitation providers: A mixed methods study. NeuroRehabilitation 40:4, pages 545-552.
Crossref
Martha I. Betancur, Hannah D. Mason, Melissa Alvarado-Velez, Phillip V. Holmes, Ravi V. Bellamkonda & Lohitash Karumbaiah. (2017) Chondroitin Sulfate Glycosaminoglycan Matrices Promote Neural Stem Cell Maintenance and Neuroprotection Post-Traumatic Brain Injury. ACS Biomaterials Science & Engineering 3:3, pages 420-430.
Crossref
Noah D. SilverbergPaul K. CraneKristen Dams-O'ConnorJames HoldnackBrian J. IvinsRael T. LangeGeoffrey T. ManleyMichael McCreaGrant L. Iverson. (2017) Developing a Cognition Endpoint for Traumatic Brain Injury Clinical Trials. Journal of Neurotrauma 34:2, pages 363-371.
Crossref
Harry Hallock, Daniel Collins, Amit Lampit, Kiran Deol, Jennifer Fleming & Michael Valenzuela. (2016) Cognitive Training for Post-Acute Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Frontiers in Human Neuroscience 10.
Crossref
Qiuhua Shen, John B. Hiebert, Julie Hartwell, Amanda R. Thimmesch & Janet D. Pierce. (2016) Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes. Worldviews on Evidence-Based Nursing 13:5, pages 380-389.
Crossref
Peter BraggeAnneliese SynnotAndrew I. MaasDavid K. MenonD. James CooperJeffrey V. RosenfeldRussell L. Gruen. (2016) A State-of-the-Science Overview of Randomized Controlled Trials Evaluating Acute Management of Moderate-to-Severe Traumatic Brain Injury. Journal of Neurotrauma 33:16, pages 1461-1478.
Crossref
Daniel L. Haus, Luci López-Velázquez, Eric M. Gold, Kelly M. Cunningham, Harvey Perez, Aileen J. Anderson & Brian J. Cummings. (2016) Transplantation of human neural stem cells restores cognition in an immunodeficient rodent model of traumatic brain injury. Experimental Neurology 281, pages 1-16.
Crossref
Riza Gultekin, Sean Huang, Ornella Clavisi, Loyal Pattuwage, Thomas C. König & Russell Gruen. (2016) Pharmacological interventions in traumatic brain injury: Can we rely on systematic reviews for evidence?. Injury 47:3, pages 516-524.
Crossref
Helen M. BramlettW. Dalton Dietrich. (2015) Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurological Outcomes. Journal of Neurotrauma 32:23, pages 1834-1848.
Crossref
Dominic Dougall, Norman Poole & Niruj Agrawal. (2015) Pharmacotherapy for chronic cognitive impairment in traumatic brain injury. Cochrane Database of Systematic Reviews.
Crossref
Douglas H. SmithRamona R. HicksVictoria E. JohnsonDebra A. BergstromDiana M. CummingsLinda J. NobleDavid HovdaMichael WhalenStephen T. AhlersMichelle LaPlacaFrank C. TortellaAnn-Christine DuhaimeC. Edward Dixon. (2015) Pre-Clinical Traumatic Brain Injury Common Data Elements: Toward a Common Language Across Laboratories. Journal of Neurotrauma 32:22, pages 1725-1735.
Crossref
David X Cifu & Blessen C EapenAjit B Pai. 2015. Traumatic Brain Injury Rehabilitation Medicine. Traumatic Brain Injury Rehabilitation Medicine 46 59 .
John Scotter, Susan Hendrickson, Hani J Marcus & Mark H Wilson. (2015) Prognosis of patients with bilateral fixed dilated pupils secondary to traumatic extradural or subdural haematoma who undergo surgery: a systematic review and meta-analysis. Emergency Medicine Journal 32:8, pages 654-659.
Crossref
Martin Furr & Stephen ReedYvette S. Nout‐Lomas. 2015. Equine Neurology. Equine Neurology 406 428 .
Yanlu Zhang, Michael ChoppYuling Meng, Zheng Gang ZhangEdith Doppler, Stefan Winter, Timothy Schallert, Asim Mahmood & Ye Xiong. (2015) Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury. Journal of Neurosurgery 122:4, pages 843-855.
Crossref
Juan Lu, Kelli W. Gary, Al Copolillo, John Ward, Janet P. Niemeier & Kate L. Lapane. (2015) Randomized Controlled Trials in Adult Traumatic Brain Injury: A Review of Compliance to CONSORT Statement. Archives of Physical Medicine and Rehabilitation 96:4, pages 702-714.
Crossref
Ike De La Peña, Paul R. Sanberg, Sandra Acosta, Shinn-Zong Lin & Cesar V. Borlongan. (2015) G-CSF as an Adjunctive Therapy with Umbilical Cord Blood Cell Transplantation for Traumatic Brain Injury. Cell Transplantation 24:3, pages 447-457.
Crossref
Jaclyn A. Stephens, Karen-Nicole C. Williamson & Marian E. Berryhill. (2015) Cognitive Rehabilitation After Traumatic Brain Injury. OTJR: Occupation, Participation and Health 35:1, pages 5-22.
Crossref
Junhong Yu, Helena M. K. Tam & Tatia M. C. Lee. (2015) Traumatic Brain Injury Rehabilitation in Hong Kong: A Review of Practice and Research. Behavioural Neurology 2015, pages 1-8.
Crossref
Karen A. Schwab, Larus S. Gudmudsson & Henry L. Lew. 2015. Traumatic Brain Injury, Part II. Traumatic Brain Injury, Part II 649 659 .
Anna SandestigBertil RomnerPer-Olof Grände. (2014) Therapeutic Hypothermia in Children and Adults with Severe Traumatic Brain Injury. Therapeutic Hypothermia and Temperature Management 4:1, pages 10-20.
Crossref
Juan LuCecilie RoeEline AasKate L. LapaneJanet NiemeierJuan Carlos Arango-LasprillaNada Andelic. (2013) Traumatic Brain Injury: Methodological Approaches To Estimate Health and Economic Outcomes. Journal of Neurotrauma 30:23, pages 1925-1933.
Crossref
Jessie S. Truettner, Dario Motti & W. Dalton Dietrich. (2013) MicroRNA overexpression increases cortical neuronal vulnerability to injury. Brain Research 1533, pages 122-130.
Crossref
Lisa A. Brenner, Adam S. Hoffberg, Robert D. Shura, Nazanin Bahraini & Hal S. Wortzel. (2013) Interventions for Mood-Related Issues Post Traumatic Brain Injury: Novel Treatments and Ongoing Limitations of Current Research. Current Physical Medicine and Rehabilitation Reports 1:3, pages 143-150.
Crossref
Joshua B. Cantor & Shinakee Gumber. (2013) Use of Complementary and Alternative Medicine in Treating Individuals with Traumatic Brain Injury. Current Physical Medicine and Rehabilitation Reports 1:3, pages 159-168.
Crossref
Peter Baxter. (2013) Acute and chronic management of traumatic brain injury. Developmental Medicine & Child Neurology 55:8, pages 680-680.
Crossref
Chun-Shu Piao, Bogdan A. Stoica, Junfang Wu, Boris Sabirzhanov, Zaorui Zhao, Rainier Cabatbat, David J. Loane & Alan I. Faden. (2013) Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury. Neurobiology of Disease 54, pages 252-263.
Crossref
Hanna AlgattasJason H. Huang. (2013) Neurotrauma and Repair Research: Traumatic Brain Injury (TBI) and its Treatments. Biomedical Engineering and Computational Biology 5, pages BECB.S10968.
Crossref
Dhananjay R. NamjoshiCraig GoodWai Hang ChengWilliam PanenkaDarrin Richards, Peter A. CriptonCheryl L. Wellington. (2013) Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective. Disease Models & Mechanisms.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.