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Current Eye Research Volume 34, 2009 - Issue 12
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Original Article

Microplasmin Degrades Fibronectin and Laminin at Vitreoretinal Interface and Outer Retina during Enzymatic Vitrectomy

Wu ChenSchool of Life Science and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, P.R. China
,
Wei MoDepartment of Molecular Genetics, Shanghai Medical School and Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, Shanghai, P.R. China
,
Ke SunDepartment of Molecular Genetics, Shanghai Medical School and Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, Shanghai, P.R. China
,
Xin HuangEye and ENT Hospital, Fudan University, Shanghai, P.R. China
,
Yan-lin ZhangDepartment of Molecular Genetics, Shanghai Medical School and Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, Shanghai, P.R. ChinaCorrespondence[email protected]
&
Hou-yan SongDepartment of Molecular Genetics, Shanghai Medical School and Key Laboratory of Molecular Medicine, Ministry of Education, Fudan University, Shanghai, P.R. ChinaCorrespondence[email protected]
Pages 1057-1064 | Received 02 Dec 2008, Accepted 03 Sep 2009, Published online: 03 Dec 2009

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Irini P. Chatziralli, George P. Theodossiadis, Efstratios Parikakis, Ioannis Datseris & Panagiotis Theodossiadis. (2016) Complications of intravitreal ocriplasmin for vitreomacular traction and macular hole: a prospective spectral-domain optical coherence tomography study. Cutaneous and Ocular Toxicology 35:4, pages 263-269.
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Ruwan A Silva, Darius M Moshfeghi & Theodore Leng. (2014) Retinal breaks due to intravitreal ocriplasmin. Clinical Ophthalmology 8, pages 1591-1594.
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Francisco R Stefanini, Maurício Maia, Paulo Falabella, Marcel Pfister, Moritz Niemeyer, Amir H Kashani, Mark S Humayun & Michael J Koss. (2014) Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion. Clinical Ophthalmology 8, pages 847-856.
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Su Jeong Song & William E Smiddy. (2014) Ocriplasmin for symptomatic vitreomacular adhesion: an evidence-based review of its potential. Core Evidence 9, pages 51-59.
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Marc D de Smet & Miguel Castilla. (2013) Ocriplasmin for diabetic retinopathy. Expert Opinion on Biological Therapy 13:12, pages 1741-1747.
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Vera K Schmit-Eilenberger & Albert J Augustin. (2013) Ocriplasmin opens up new avenues in the therapy of vitreomacular traction. Expert Review of Ophthalmology 8:5, pages 407-411.
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Qintuo Pan, Shengjian Lu, Mengyun Li, Huirong Pan, Lixu Wang, Yiyang Mao, Wencan Wu & Yikui Zhang. (2022) Vitrectomy and ILM peeling in rhesus macaque: pitfalls and tips for success. Eye 37:11, pages 2257-2264.
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Rong-zeng Liu, Ya-jun Hu, Tian-fa Wang, Jin-chao Yu, Yu-xiong Wang, Yan-ling Zhang, Min Yu & Bing Zhao. (2023) A novel recombinant human microplasminogen induced complete posterior vitreous detachment without morphological change of retina in juvenile rabbits. Experimental Eye Research 230, pages 109465.
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James E. Neffendorf, Varo Kirthi, Cristina Soare & Timothy L. Jackson. (2021) The Effect of Intravitreal Ocriplasmin on Hue Discrimination. Optometry and Vision Science 98:12, pages 1394-1399.
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Amy Yuan, Dong Yang & Lisa Olmos de Koo. (2021) Current Trends in Macular Hole Repair. Current Surgery Reports 9:12.
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Swetha Bindu Velaga, Muneeswar Gupta Nittala, Michael S Ip, Luc Duchateau & SriniVas R Sadda. (2021) Post hoc analysis of ellipsoid zone changes beyond the central subfield in symptomatic vitreomacular adhesion patients from the OASIS trial. BMJ Open Ophthalmology 6:1, pages e000648.
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Alessandro Arrigo, Alessandro Calamuneri, Alessandro Bordato, Emanuela Aragona, Luisa Pierro, Francesco Bandello & Maurizio Battaglia Parodi. (2020) Vitreomacular traction quantitative cutoffs for the assessment of resolution after ocriplasmin intravitreal treatment. Scientific Reports 10:1.
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Alberto Mazzini, Francesca Palermo, Valeria Pagliei, Sabrina Romanò, Massimiliano Papi, Giovanna Zimatore, Benedetto Falsini, Stanislao Rizzo, Marco De Spirito, Gabriele Ciasca & Angelo Maria Minnella. (2020) A time-dependent study of nano-mechanical and ultrastructural properties of internal limiting membrane under ocriplasmin treatment. Journal of the Mechanical Behavior of Biomedical Materials 110, pages 103853.
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Souska ZandiFlorentina FreibergVeronika VaclavikIsabel B. PfisterPeter G. TraineCagdas KayaStephan MichelsJustus G. Garweg. (2020) Morphological Reconstitution and Persistent Changes After Intravitreal Ocriplasmin for Vitreomacular Traction and Macular Hole. Journal of Ocular Pharmacology and Therapeutics 36:2, pages 126-132.
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Claudio Furino, Alfredo Niro, Luigi Sborgia, Michele Reibaldi, Francesco Boscia & Giovanni Alessio. (2020) Visual functional changes after ocriplasmin injection for vitreomacular traction: A microperimetric analysis. Taiwan Journal of Ophthalmology 0:0, pages 0.
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Lorenzo Iuliano, Giovanni Fogliato, Roberta Colombo, Riccardo Sacconi, Giuseppe Querques, Francesco Bandello & Marco Codenotti. (2019) Reduced perfusion density of superficial retinal capillary plexus after intravitreal ocriplasmin injection for idiopathic vitreomacular traction. BMC Ophthalmology 19:1.
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Peng SunRachel M. Tandias, Gina Yu & Jorge G. Arroyo. (2019) SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS AND VISUAL OUTCOME AFTER TREATMENT FOR VITREOMACULAR TRACTION. Retina 39:6, pages 1054-1060.
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Christine P.S. Ho & Timothy Y.Y. Lai. (2019) Pharmacotherapy for Choroidal Neovascularization Due to Uncommon Causes. Current Pharmaceutical Design 24:41, pages 4882-4895.
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Akshay S. Thomas, Francisco A. Folgar, Glenn J. Jaffe, Cynthia A. Toth & Tamer H. Mahmoud. (2019) Subfoveal Lucency after Treatment of Vitreomacular Traction without Macular Hole in the Phase 3 Trials of Ocriplasmin Vitreolysis. Ophthalmology Retina 3:1, pages 42-52.
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Matteo G. Cereda, Chiara Preziosa, Isabella D'Agostino, Mariano Cozzi, Ferdinando Bottoni, Marco Pellegrini, Andrea Giani & Giovanni Staurenghi. (2018) OCRIPLASMIN FOR VITREOMACULAR TRACTION: LOOKING OUTSIDE THE MACULA. Retina 38:8, pages 1541-1548.
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Majed Felemban, Birthe Dorgau, Nicola Claire Hunt, Dean Hallam, Darin Zerti, Roman Bauer, Yuchun Ding, Joseph Collin, David Steel, Natalio Krasnogor, Jumana Al-Aama, Susan Lindsay, Carla Mellough & Majlinda Lako. (2018) Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix. Acta Biomaterialia 74, pages 207-221.
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Nicholas Chow, Thomas Hong & Andrew Chang. (2018) Multimodal imaging of macular subretinal deposits following intravitreal ocriplasmin injection. American Journal of Ophthalmology Case Reports 9, pages 80-84.
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David G. BirchMatthew S. BenzDaniel M. MillerAndrew N. AntoszykJoseph Markoff, Petra KozmaEsmeralda MeunierRobert C. Sergott. (2018) EVALUATION OF FULL-FIELD ELECTRORETINOGRAM REDUCTIONS AFTER OCRIPLASMIN TREATMENT. Retina 38:2, pages 364-378.
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Ricarda G. Schumann, Julian Langer, Denise Compera, Katharina Luedtke, Markus M. Schaumberger, Thomas Kreutzer, Wolfgang J. Mayer, Armin Wolf & Siegfried G. Priglinger. (2017) Assessment of intravitreal ocriplasmin treatment for vitreomacular traction in clinical practice. Graefe's Archive for Clinical and Experimental Ophthalmology 255:11, pages 2081-2089.
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Bart Jonckx, Michael Porcu, Aurelie Candi, Isabelle Etienne, Philippe Barbeaux & Jean H. M. Feyen. (2017) Assessment of Ocriplasmin Effects on the Vitreoretinal Compartment in Porcine and Human Model Systems. Journal of Ophthalmology 2017, pages 1-12.
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Michael W. StewartMichael W. Stewart. 2017. Diabetic Retinopathy. Diabetic Retinopathy 187 204 .
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Yuji Itoh & Justis P. Ehlers. (2016) ELLIPSOID ZONE MAPPING AND OUTER RETINAL CHARACTERIZATION AFTER INTRAVITREAL OCRIPLASMIN. Retina 36:12, pages 2290-2296.
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Elena Vecino, F.David Rodriguez, Noelia Ruzafa, Xandra Pereiro & Sansar C. Sharma. (2016) Glia–neuron interactions in the mammalian retina. Progress in Retinal and Eye Research 51, pages 1-40.
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João Figueira, David Martins, Bernardete Pessoa, Natália Ferreira, Angelina Meireles, António Sampaio, Ângela Carneiro, Fernanda Vaz, João Nascimento, Natacha Moreno, José Roque, Manuel Domingues, Rita Flores, Carla Teixeira, Eduardo Conde, Filipe Henriques, Helena Proença, José Pita Negrão, Marisa Barbosa, Rufino Silva, Sara Vaz-Pereira, Pedro Pereira Neves, Nuno Gomes & Miguel Raimundo. (2016) The Portuguese Experience with Ocriplasmin in Clinical Practice. Ophthalmic Research 56:4, pages 186-192.
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