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Original Article

Evaluation of Protective Effects of Trehalose on Desiccation of Epithelial Cells in Three Dimensional Reconstructed Human Corneal Epithelium

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Pages 982-989 | Received 15 Feb 2012, Accepted 03 Jun 2012, Published online: 25 Jun 2012

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Read on this site (4)

L Caretti, A La Gloria Valerio, R Piermarocchi, G Badin, G Verzola, F Masarà, T Scalora & C Monterosso. (2019) Efficacy of carbomer sodium hyaluronate trehalose vs hyaluronic acid to improve tear film instability and ocular surface discomfort after cataract surgery. Clinical Ophthalmology 13, pages 1157-1163.
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Antonio J Mateo Orobia, Paula Casas Pascual, José Á Cristóbal Bescós, Diana Perez García, Carlos Peiro Embid, M Ángeles del Buey Sayas, Valentyna Korobko Kulikova & Noelia Lafuente Ojeda. (2017) Effects of 3% trehalose as an adjuvant treatment after LASIK. Clinical Ophthalmology 11, pages 347-353.
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Jared Hara, Jordan Tottori, Megan Anders, Smritee Dadhwal, Prashanth Asuri & Maryam Mobed-Miremadi. (2017) Trehalose effectiveness as a cryoprotectant in 2D and 3D cell cultures of human embryonic kidney cells. Artificial Cells, Nanomedicine, and Biotechnology 45:3, pages 609-616.
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Juan Carlos Pinto-Bonilla, Alberto del Olmo-Jimeno, Fernando Llovet-Osuna & Emiliano Hernández-Galilea. (2015) A randomized crossover study comparing trehalose/hyaluronate eyedrops and standard treatment: patient satisfaction in the treatment of dry eye syndrome. Therapeutics and Clinical Risk Management 11, pages 595-603.
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Articles from other publishers (20)

José-María Sánchez-González, Carmen Silva-Viguera, María Carmen Sánchez-González, Raúl Capote-Puente, Concepción De-Hita-Cantalejo, Antonio Ballesteros-Sánchez, Lydia Ballesteros-Durán, Marta-C. García-Romera & Estanislao Gutiérrez-Sánchez. (2023) Tear Film Stabilization and Symptom Improvement in Dry Eye Disease: The Role of Hyaluronic Acid and Trehalose Eyedrops versus Carmellose Sodium. Journal of Clinical Medicine 12:20, pages 6647.
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Antonio J. Mateo-Orobia, Eduardo del Prado Sanz, Alejandro Blasco-Martínez, Luis E. Pablo-Júlvez, Sarah Farrant & Frédéric Chiambaretta. (2023) Efficacy of artificial tears containing trehalose and hyaluronic acid for dry eye disease in women aged 42–54 versus ≥ 55 years. Contact Lens and Anterior Eye 46:4, pages 101845.
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Sheetal Brar, Hemanth Reddy Vanga & Sri Ganesh. (2021) Comparison of efficacy of trehalose-based eye drops versus topical 0.1% Hyaluronic Acid for management of clinically significant dry eye using non-invasive investigational modalities. International Ophthalmology 41:10, pages 3349-3359.
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Eva HernandezClémence TaisneMarion LussignolAudrey EsclatineMarc Labetoulle. (2021) Commercially Available Eye Drops Containing Trehalose Protect Against Dry Conditions via Autophagy Induction. Journal of Ocular Pharmacology and Therapeutics 37:7, pages 386-393.
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Melania Olivieri, Martina Cristaldi, Salvatore Pezzino, Giorgia Spampinato, Roberta Corsaro, Carmelina Daniela Anfuso, Gabriella Lupo & Dario Rusciano. (2021) Poly 2-methacryloyloxyethyl Phosphorylcholine Protects Corneal Cells and Contact Lenses from Desiccation Damage. Optometry and Vision Science 98:2, pages 159-169.
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Eduardo J. Polanía-Barón & Alberto Haber. (2021) Efecto de la trehalosa tópica al 3% en la velocidad de epitelización corneal en pacientes operados de queratectomía fotorrefractiva. Revista Mexicana de Oftalmología 95:2S, pages 71-75.
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Hakika ERDOGAN & Orkun MUHSİNOGLU. (2021) Effect of Postoperative Administration of Hyaluronic Acid/Trehalose Drop on Corneal Healing After Phacoemulsification Surgery. Black Sea Journal of Health Science 4:1, pages 17-21.
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I.E. Panova, A.V. Titov & D.R. Mirsaitova. (2020) The effects of a trehalose-based drug used after laser keratorefractive surgeries. Vestnik oftal'mologii 136:4, pages 110.
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Saba Sajjad, Ji-San Ha, Seong-Hyun Seo, Tae-Sung Yoon, Hee-Mock Oh, Hyung-Gwan Lee & Sunghyun Kang. (2020) Differential proteomic analyses of green microalga Ettlia sp. at various dehydration levels. Plant Physiology and Biochemistry 146, pages 198-210.
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Najam A. Sharif. 2020. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 163 208 .
Trailokyanath Panigrahi, Shivapriya Shivakumar, Rohit Shetty, Sharon D'souza, Everette Jacob Remington Nelson, Swaminathan Sethu, Nallathambi Jeyabalan & Arkasubhra Ghosh. (2019) Trehalose augments autophagy to mitigate stress induced inflammation in human corneal cells. The Ocular Surface 17:4, pages 699-713.
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Yuriy Petrenko, Milada Chudickova, Irena Vackova, Tomas Groh, Eliska Kosnarova, Jitka Cejkova, Karolina Turnovcova, Alexander Petrenko, Eva Sykova & Sarka Kubinova. (2019) Clinically Relevant Solution for the Hypothermic Storage and Transportation of Human Multipotent Mesenchymal Stromal Cells. Stem Cells International 2019, pages 1-11.
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S. A. Rykov, I. V. Shargorodska, N. S. Lavryk & L. V Kornilov L. V. (2019) RESEARCH OF CONSERVATIVE EFFICIENCY TREATMENT OF PATIENTS WITH DESTRUCTIVE LESION (ULCER) OF THE CORNEA. Bulletin of Problems Biology and Medicine 1:2, pages 175.
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Najam A. Sharif. 2019. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 1 46 .
Shivapriya Shivakumar, Trailokyanath Panigrahi, Rohit Shetty, Murali Subramani, Arkasubhra Ghosh & Nallathambi Jeyabalan. (2018) Chloroquine Protects Human Corneal Epithelial Cells from Desiccation Stress Induced Inflammation without Altering the Autophagy Flux. BioMed Research International 2018, pages 1-13.
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Marta Vicario-de-la-Torre, María Caballo-González, Eva Vico, Laura Morales-Fernández, Pedro Arriola-Villalobos, Beatriz de las Heras, José Benítez-del-Castillo, Manuel Guzmán, Thomas Millar, Rocío Herrero-Vanrell & Irene Molina-Martínez. (2018) Novel Nano-Liposome Formulation for Dry Eyes with Components Similar to the Preocular Tear Film. Polymers 10:4, pages 425.
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Panita SuwannoiMullika ChomnawangNarong SarisutaStephan ReichlChristel C. Müller-Goymann. (2017) Development of Acyclovir-Loaded Albumin Nanoparticles and Improvement of Acyclovir Permeation Across Human Corneal Epithelial T Cells. Journal of Ocular Pharmacology and Therapeutics 33:10, pages 743-752.
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Lyndon Jones, Laura E. Downie, Donald Korb, Jose M. Benitez-del-Castillo, Reza Dana, Sophie X. Deng, Pham N. Dong, Gerd Geerling, Richard Yudi Hida, Yang Liu, Kyoung Yul Seo, Joseph Tauber, Tais H. Wakamatsu, Jianjiang Xu, James S. Wolffsohn & Jennifer P. Craig. (2017) TFOS DEWS II Management and Therapy Report. The Ocular Surface 15:3, pages 575-628.
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Piotr A. Wozniak, Doreen Schmidl, Ahmed M. Bata, Klemens Fondi, Katarzyna J. Witkowska, Valentin Aranha dos Santos, Carina Baar, Kim I. Room, Johannes Nepp, Isabella Baumgartner, Alina Popa-Cherecheanu, Gerhard Garhöfer, René M. Werkmeister & Leopold Schmetterer. (2017) Effect of different lubricant eye gels on tear film thickness as measured with ultrahigh-resolution optical coherence tomography. Acta Ophthalmologica 95:4, pages e307-e313.
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Frédéric Chiambaretta, Serge Doan, Marc Labetoulle, Nicolas Rocher, Lamia El Fekih, Riadh Messaoud, Moncef Khairallah & Christophe Baudouin. (2016) A Randomized, Controlled Study of the Efficacy and Safety of a New Eyedrop Formulation for Moderate to Severe Dry Eye Syndrome. European Journal of Ophthalmology 27:1, pages 1-9.
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