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Current Eye Research Volume 38, 2013 - Issue 3
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Research Article

Hydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats

Yanqing FengDepartment of Ophthalmology, Shanghai Kongjiang Hospital ShanghaiChina
,
Ruobing WangDepartment of Ophthalmology, First People's Hospital affiliated to Shanghai Jiaotong University ShanghaiChinaCorrespondence[email protected] [email protected]
,
Jiajun XuDepartment of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University ShanghaiChina
,
Jingchuan SunGraduates Management Unit, Second Military Medical University ShanghaiChina
,
Tao XuGraduates Management Unit, Second Military Medical University ShanghaiChina
,
Qing GuDepartment of Ophthalmology, First People's Hospital affiliated to Shanghai Jiaotong University ShanghaiChina
&
Xingwei WuDepartment of Ophthalmology, First People's Hospital affiliated to Shanghai Jiaotong University ShanghaiChinaCorrespondence[email protected] [email protected]
 show all
Pages 396-404 | Received 13 Feb 2012, Accepted 07 Nov 2012, Published online: 19 Dec 2012

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Ye Tao, Lei Geng, Wei-Wei Xu, Li-Min Qin, Guang-Hua Peng & Yi-Fei Huang. (2016) The potential utilizations of hydrogen as a promising therapeutic strategy against ocular diseases. Therapeutics and Clinical Risk Management 12, pages 799-806.
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Articles from other publishers (26)

Yuqing Du, Jie Wang, Weijing Fan, Renyan Huang, Hongfei Wang & Guobin Liu. (2023) Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation. International Wound Journal 20:10, pages 4394-4409.
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Si-Yu Li, Rong-Yue Xue, Hao Wu, Ning Pu, Dong Wei, Na Zhao, Zong-Ming Song & Ye Tao. (2023) Novel Role of Molecular Hydrogen: The End of Ophthalmic Diseases?. Pharmaceuticals 16:11, pages 1567.
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Rong Wu, Sheng Huang, Jin-feng Xie, Nian-lian Wen, Min Wen & Su-e Zhong. (2023) CircRNA SCAR Improves High-Glucose-Induced Mitochondrial Dysfunction and Permeability Damage in Retinal Microvascular Endothelial Cells. Hormone and Metabolic Research 55:08, pages 555-562.
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Fei Xie, Yifei Song, Yang Yi, Xue Jiang, Shiwen Ma, Chen Ma, Junyu Li, Ziyi Zhanghuang, Mengyu Liu, Pengxiang Zhao & Xuemei Ma. (2023) Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside. Pharmaceuticals 16:4, pages 541.
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Inesa LelyteZubair AhmedSimon Kaja & Giedrius Kalesnykas. (2022) Structure–Function Relationships in the Rodent Streptozotocin-Induced Model for Diabetic Retinopathy: A Systematic Review. Journal of Ocular Pharmacology and Therapeutics 38:4, pages 271-286.
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晓艺 张. (2022) Advances in Hydrogen Medicine Intervention in Diabetes Mellitus. Nursing Science 11:03, pages 347-353.
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Yun Hu, Xiaoyan Feng, Junhui Chen, Yan Wu & Liuyan Shen. (2021) Hydrogen‑rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO‑1 signaling pathway after traumatic brain injury. Experimental and Therapeutic Medicine 23:2.
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Cemal Orhan, Besir Er, Patrick Brice Defo Deeh, Ahmet Alp Bilgic, Sara Perez Ojalvo, James Richard Komorowski & Kazim Sahin. (2021) Different Sources of Dietary Magnesium Supplementation Reduces Oxidative Stress by Regulation Nrf2 and NF-κB Signaling Pathways in High-Fat Diet Rats. Biological Trace Element Research 199:11, pages 4162-4170.
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Sergej M. Ostojic. (2021) Hydrogen as a Potential Therapeutic in Obesity: Targeting the Brain. Trends in Endocrinology & Metabolism 32:4, pages 191-193.
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Hiroshi Takahashi. (2021) Application of Hydrogen in Ophthalmology. Current Pharmaceutical Design 27:5, pages 592-594.
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Bingjie Jiang, Yunping Li, Weimin Dai, An Wu, Huayong Wu & Dandan Mao. (2021) Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. Acta Cirúrgica Brasileira 36:8.
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Shu-Huai Tsai, Wankun Xie, Min Zhao, Robert H. RosaJr.Jr., Travis W. Hein & Lih Kuo. (2018) Alterations of Ocular Hemodynamics Impair Ophthalmic Vascular and Neuroretinal Function. The American Journal of Pathology 188:3, pages 818-827.
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Jiangchun Wu, Ruobing Wang, Dianxu Yang, Wenbin Tang, Zeli Chen, Qinglei Sun, Lin Liu & Rongyu Zang. (2018) Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. Biochemical and Biophysical Research Communications 495:4, pages 2462-2468.
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Jialiang Guo, Weichong Dong, Lin Jin, Pengcheng Wang, Zhiyong Hou & Yingze Zhang. (2017) Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin. International Orthopaedics 41:10, pages 2119-2128.
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Edy Siswantoro, Nasrul Hadi Purwanto & Sutomo  . (2017) Effectiveness of Alkali Water Consumption to Reduce Blood Sugar Levels in Diabetes Mellitus Type 2. Journal of Diabetes Mellitus 07:04, pages 249-264.
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Yaxing Zhang, Jingting Xu, Zhiyuan Long, Chen Wang, Ling Wang, Peng Sun, Ping Li & Tinghuai Wang. (2016) Hydrogen (H2) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways. Frontiers in Pharmacology 7.
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Lin Liu, Qinglei Sun, Ruobing Wang, Zeli Chen, Jiangchun Wu, Fangzhou Xia & Xian-qun Fan. (2016) Methane attenuates retinal ischemia/reperfusion injury via anti-oxidative and anti-apoptotic pathways. Brain Research 1646, pages 327-333.
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Tao Chen, Ye Tao, Weiming Yan, Guoqing Yang, Xuemin Chen, Ruidan Cao, Lei Zhang, Junhui Xue & Zuoming Zhang. (2016) Protective effects of hydrogen-rich saline against N-methyl-N-nitrosourea-induced photoreceptor degeneration. Experimental Eye Research 148, pages 65-73.
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Qian Zhang, Ye Tao & Zuo-Ming Zhang. (2016) Hydrogen-rich Saline is ineffective in oxygen-induced retinopathy. Life Sciences 153, pages 17-22.
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Ruobing Wang, Jiangchun Wu, Zeli Chen, Fangzhou Xia, Qinglei Sun & Lin Liu. (2016) Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury. Brain Research 1632, pages 82-90.
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Lijuan Yuan & Jianliang Shen. (2016) Hydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?. Clinics 71:9, pages 544-549.
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Masatoshi Ichihara, Sayaka Sobue, Mikako Ito, Masafumi Ito, Masaaki Hirayama & Kinji Ohno. (2015) Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles -. Medical Gas Research 5:1.
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Feng Wu, Yihua Qiu, Guangming Ye, Hede Luo, Junsong Jiang, Feng Yu, Wei Zhou, Shuai Zhang & Jinzhong Feng. (2015) Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. Cardiovascular Pathology 24:5, pages 294-303.
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Fusheng Yang, Zaoxiao Zhang, Dengfeng Gao, Yuqi Wang & Xuyang Chen. (2014) Simulation study on the outlet flow dynamics of a hydride-based hydrogen storage canister for medical use. International Journal of Hydrogen Energy 39:12, pages 6548-6557.
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Krisztina Szabadfi, Erika Pinter, Dora Reglodi & Robert Gabriel. 2014. 1 121 .
Akinobu Takaki, Daisuke Kawai & Kazuhide Yamamoto. (2013) Multiple Hits, Including Oxidative Stress, as Pathogenesis and Treatment Target in Non-Alcoholic Steatohepatitis (NASH). International Journal of Molecular Sciences 14:10, pages 20704-20728.
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