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Original Article

Neural retinas promote cell division and fibre differentiation in lens epithelial explants

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Pages 827-834 | Received 18 Oct 1983, Accepted 28 Mar 1984, Published online: 02 Jul 2009

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Read on this site (8)

Kevin A Maruno, Frank J Lovicu, Coral G Chamberlain & John Wmcavoy. (2002) Apoptosis is a feature of TGFß‐induced cataract. Clinical and Experimental Optometry 85:2, pages 76-82.
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Mark W. Schulz, Coral G. Chamberlain & John W. McAvoy. (1997) Binding of FGF-1 and FGF-2 to Heparan Sulphate Proteoglycans of the Mammalian Lens Capsule. Growth Factors 14:1, pages 1-13.
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C. G. Chamberlain, J. W. McAvoy & N. A. Richardson. (1991) The Effects of Insulin and Basic Fibroblast Growth Factor on Fibre Differentiation in Rat Lens Epithelial Explants. Growth Factors 4:3, pages 183-188.
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C. M. Parmigiani & J. W. McAvoy. (1991) The roles of laminin and fibronectin in the development of the lens capsule. Current Eye Research 10:6, pages 501-511.
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Coral G. Chamberlain & John W. McAvoy. (1989) Induction of Lens Fibre Differentiation by Acidic and Basic Fibroblast Growth Factor (FGF). Growth Factors 1:2, pages 125-134.
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Coral G. Chamberlain & John W. McAvoy. (1987) Evidence that fibroblast growth factor promotes lens fibre differentiation. Current Eye Research 6:9, pages 1165-1168.
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J. W. McAvoy & N. A. Richardson. (1986) Nuclear pyknosis during lens fibre differentiation in epithelial explants. Current Eye Research 5:9, pages 711-715.
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J. W. McAvoy & J. McDonald. (1984) Proliferation of lens epithelial explants in culture increases with age of donor rat. Current Eye Research 3:9, pages 1151-1153.
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Articles from other publishers (46)

Justin Parreno, Grace Emin, Michael P. Vu, Jackson T. Clark, Sandeep Aryal, Shaili D. Patel & Catherine Cheng. (2022) Methodologies to unlock the molecular expression and cellular structure of ocular lens epithelial cells. Frontiers in Cell and Developmental Biology 10.
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S.J. Das, T.F.L Wishart, K. Jandeleit-Dahm & F.J. Lovicu. (2020) Nox4-mediated ROS production is involved, but not essential for TGFβ-induced lens EMT leading to cataract. Experimental Eye Research 192, pages 107918.
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Toshiaki Mochizuki, Yutaka Kojima, Yuko Nishiwaki, Tetsuya Harakuni & Ichiro Masai. (2018) Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish. Development 145:20.
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Dong Wang, Eddie Wang, Kelsey Liu, Chun-hong Xia, Song Li & Xiaohua Gong. (2017) Roles of TGFβ and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro. Scientific Reports 7:1.
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Thuzar Thein, Jimmy de Melo, Cristina Zibetti, Brian S. Clark, Felicia Juarez & Seth Blackshaw. (2016) Control of lens development by Lhx2-regulated neuroretinal FGFs. Development.
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Toshiaki Mochizuki & Ichiro Masai. (2014) The lens equator: A platform for molecular machinery that regulates the switch from cell proliferation to differentiation in the vertebrate lens. Development, Growth & Differentiation 56:5, pages 387-401.
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Lena Gunhaga. (2011) The lens: a classical model of embryonic induction providing new insights into cell determination in early development. Philosophical Transactions of the Royal Society B: Biological Sciences 366:1568, pages 1193-1203.
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Judith A. West-Mays, Guiseppe Pino & Frank J. Lovicu. (2010) Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis. Progress in Retinal and Eye Research 29:2, pages 135-143.
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Christina E. Lorén, John W. Schrader, Ulf Ahlgren & Lena Gunhaga. (2009) FGF signals induce Caprin2 expression in the vertebrate lens. Differentiation 77:4, pages 386-394.
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Michael D. O'Connor, Elizabeth D. Wederell, Robert de Iongh, Frank J. Lovicu & John W. McAvoy. (2008) Generation of transparency and cellular organization in lens explants. Experimental Eye Research 86:5, pages 734-745.
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F.J. Lovicu & J.W. McAvoy. 2008. Animal Models in Eye Research. Animal Models in Eye Research 134 147 .
LEON F. GARNER, ALISTAIR W. STEWART, HELEN OWENS, ROBERT F. KINNEAR & MICHAEL J. FRITH. (2006) The Nepal Longitudinal Study: Biometric Characteristics of Developing Eyes. Optometry and Vision Science 83:5, pages 274-280.
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F.J. Lovicu & J.W. McAvoy. (2005) Growth factor regulation of lens development. Developmental Biology 280:1, pages 1-14.
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Shaojun Yang, Shuh-Tuan Wang-Su, Huicong Cai & B.J. Wagner. (2002) Changes in Three Types of Ubiquitin mRNA and Ubiquitin-protein Conjugate Levels During Lens Development. Experimental Eye Research 74:5, pages 595-604.
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Fang-Cheng Hung, Shulei Zhao, Qin Chen & Paul A Overbeek. (2002) Retinal ablation and altered lens differentiation induced by ocular overexpression of BMP7. Vision Research 42:4, pages 427-438.
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HIDEAKI OHARAZAWA, NOBUHIRO IBARAKI, LI-REN LIN & VENKAT N REDDY. (1999) The Effects of Extracellular Matrix on Cell Attachment, Proliferation and Migration in a Human Lens Epithelial Cell Line. Experimental Eye Research 69:6, pages 603-610.
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Takashi Tanaka, Tohru Tsujimura, Kiyoshi Takeda, Ayako Sugihara, Akiko Maekawa, Nobuyuki Terada, Nobuaki Yoshida & Shizuo Akira. (2003) Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. Genes to Cells 3:12, pages 801-810.
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ERIK JAN KLOK, NICOLETTE H LUBSEN, CORAL G CHAMBERLAIN & JOHN W McAVOY. (1998) Induction and Maintenance of Differentiation of Rat Lens Epithelium by FGF-2, Insulin and IGF-1. Experimental Eye Research 67:4, pages 425-431.
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HUICONG CAI, INDERPAL SINGH & B.J. WAGNER. (1998) Gene Expression of the Proteasome in Rat Lens Development. Experimental Eye Research 66:3, pages 339-346.
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Craig M. Stolen, Mark W. Jackson & Anne E. Griep. (1997) Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens. Development 124:20, pages 4009-4017.
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Coral G. Chamberlain & John W. McAvoy. (1997) Fibre differentiation and polarity in the mammalian lens: a key role for FGF. Progress in Retinal and Eye Research 16:3, pages 443-478.
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R.U. De Iongh, F.J. Lovicu, A. Hanneken, A. Baird & J.W. McAvoy. (1996) FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth. Developmental Dynamics 206:4, pages 412-426.
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Ted W. Reid. (1994) Growth control of cornea and lens epithelial cells. Progress in Retinal and Eye Research 13:2, pages 507-554.
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Mark W. Schulz, Coral G. Chamberlain, Robbert U. de Iongh & John W. McAvoy. (1993) Acidic and basic FGF in ocular media and lens: implications for lens polarity and growth patterns. Development 118:1, pages 117-126.
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Neil A. Richardson, John W. McAvoy & Coral G. Chamberlain. (1992) Age of rats affects response of lens epithelial explants to fibroblast growth factor. Experimental Eye Research 55:5, pages 649-656.
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J. W. McAVOY, C. G. CHAMBERLAIN, R. U. De IONGH,N. A. RICHARDSON & F. J. LOVICU. (1991) The Role of Fibroblast Growth Factor in Eye Lens Development. Annals of the New York Academy of Sciences 638:1 The Fibroblas, pages 256-274.
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Brenda J. Tripathi, Ramesh C. Tripathi, Amit M. Livingston & NavaneetS. C. Borisuth. (2005) The role of growth factors in the embryogenesis and differentiation of the eye. American Journal of Anatomy 192:4, pages 442-471.
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R.M. Clayton, C.E. Patek, M.W. Head & J. Cuthbert. (1991) Ageing in the chick lens: in vitro studies. Mutation Research/DNAging 256:2-6, pages 203-220.
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Ramesh C. Tripathi, Sharon Fekrat, Brenda J. Tripathi & Navaneet S. C. Borisuth. (2008) Role of growth factors in the uveal tract of the eye as targeted to the development of new drugs. Drug Development Research 23:1, pages 1-25.
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J M Sparrow, A J Bron, N A Brown & H A Neil. (1990) Biometry of the crystalline lens in early-onset diabetes.. British Journal of Ophthalmology 74:11, pages 654-660.
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Barbara Brewitt & John I. Clark. (1990) A new method for study of normal lens developmentin vitro using pulsatile delivery of PDGF or EGF in HL-1 serum-free medium. In Vitro Cellular & Developmental Biology 26:3, pages 305-314.
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N.A. Richardson & J.W. McAvoy. (1990) Age-related changes in fibre differentiation of rat lens epithelial explants exposed to fibroblast growth factor. Experimental Eye Research 50:2, pages 203-211.
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N.A. Richardson & J.W. McAvoy. (1989) An enzyme-linked immunosorbent assay for the quantitation of DNA. Journal of Immunological Methods 125:1-2, pages 287-289.
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J. W. McAvoy & C. G. Chamberlain. (1989) Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107:2, pages 221-228.
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F.J. Lovicu & J.W. McAvoy. (1989) Structural analysis of lens epithelial explants induced to differentiate into fibres by fibroblast growth factor (FGF). Experimental Eye Research 49:3, pages 479-494.
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J.W. McAvoy. (1988) Cell lineage analysis of lens epithelial cells induced to differentiate into fibres. Experimental Eye Research 47:6, pages 869-883.
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Barbara BrewittJohn I. Clark. (1988) Growth and Transparency in the Lens, an Epithelial Tissue, Stimulated by Pulses of PDGF. Science 242:4879, pages 777-779.
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T J C Jacob, R C Humphry, E G Davies & G M Thompson. (1988) Human retinal extract stimulates the proliferation of human lens epithelial cells. Eye 2:3, pages 304-308.
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N.A. Richardson & J.W. McAvoy. (1988) Age-related changes in fibre differentiation of rat lens epithelial cells in vitro. Experimental Eye Research 46:2, pages 259-267.
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Jonathan J. Henry & Robert M. Grainger. (1987) Inductive interactions in the spatial and temporal restriction of lens-forming potential in embryonic ectoderm of Xenopus laevis. Developmental Biology 124:1, pages 200-214.
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T. J. Jacob, R. C. Humphry, E. G. Davies & G. M. Thompson. (1987) Cytological factors relating to posterior capsule opacification following cataract surgery.. British Journal of Ophthalmology 71:9, pages 659-663.
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N.A. Richardson & J.W. McAvoy. (1986) Analysis of an inductive interaction between lens and neural retina in rats of different ages. Experimental Eye Research 43:6, pages 1031-1042.
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Mary T. Campbell & John W. McAvoy. (1986) A lens fibre differentiation factor from calf neural retina. Experimental Cell Research 163:2, pages 453-466.
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J. W. McAVOY, J. WALTON & M. T. CAMPBELL. (2009) INFLUENCE OF NEURAL RETINA ON LENS FIBRE DIFFERENTIATION IN RATS. Australian and New Zealand Journal of Ophthalmology 13:2, pages 103-111.
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Judie Walton & John McAvoy. (1984) Sequential structural response of lens epithelium to retina-conditioned medium. Experimental Eye Research 39:2, pages 217-229.
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Mary T. Campbell & John W. McAvoy. (1984) Onset of fibre differentiation in cultured rat lens epithelium under the influence of neural retina-conditioned medium. Experimental Eye Research 39:1, pages 83-94.
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