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Current Eye Research Volume 11, 1992 - Issue 7
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Original Article

Influence of vehicle and anterior chamber protein concentration on cyclosporine penetration through the isolated rabbit cornea

Lisa Cheeks Department of Ophthalmology, Medical College of Georgia, Augusta, GA, USA
,
Renee L. Kaswan Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
&
Keith Green Department of Ophthalmology, Medical College of Georgia, Augusta, GA, USA; Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, USA; Department of Physiology and Endocrinology, Medical College of Georgia, Augusta, GA, USA
Pages 641-649 | Received 13 Dec 1991, Accepted 16 Jun 1992, Published online: 02 Jul 2009

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Hongzhuo Liu, Yongjun Wang & Sanming Li. (2007) Advanced delivery of Ciclosporin A: present state and perspective. Expert Opinion on Drug Delivery 4:4, pages 349-358.
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T. Loftsson & E. Stefánsson. (1997) Effect of Cyclodextrins on Topical Drug Delivery to the Eye. Drug Development and Industrial Pharmacy 23:5, pages 473-481.
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Articles from other publishers (30)

Garima Rawat, Shital Kolhe, Dhwani Rana, Sagar Salave & Derajram Benival. (2023) Exploring the Therapeutic Potential of Cyclosporine for Ophthalmic Indications by Novel Carrier Systems. Critical Reviews™ in Therapeutic Drug Carrier Systems 40:5, pages 1-45.
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Yulia Kaluzhny, Miriam W. Kinuthia, Thoa Truong, Allison M. Lapointe, Patrick Hayden & Mitchell Klausner. (2018) New Human Organotypic Corneal Tissue Model for Ophthalmic Drug Delivery Studies. Investigative Opthalmology & Visual Science 59:7, pages 2880.
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Joseph Pak, Z.J. Chen, Kay Sun, Andrzej Przekwas, Ross Walenga & Jianghong Fan. (2018) Computational modeling of drug transport across the in vitro cornea. Computers in Biology and Medicine 92, pages 139-146.
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Thorsteinn Loftsson & Einar Stefánsson. (2017) Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye. International Journal of Pharmaceutics 531:2, pages 413-423.
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Priyanka Agarwal & Ilva D. Rupenthal. (2016) In vitro and ex vivo corneal penetration and absorption models. Drug Delivery and Translational Research 6:6, pages 634-647.
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Priyanka Agarwal & Ilva D. Rupenthal. (2016) Modern approaches to the ocular delivery of cyclosporine A. Drug Discovery Today 21:6, pages 977-988.
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Marta Rodriguez-Aller, Davy Guillarme, Jean-Luc Veuthey & Robert Gurny. (2015) Strategies for formulating and delivering poorly water-soluble drugs. Journal of Drug Delivery Science and Technology 30, pages 342-351.
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Christoph Luschmann, Joerg Tessmar, Simon Schoeberl, Olaf Strauss, Carsten Framme, Karl Luschmann & Achim Goepferich. (2013) Developing an in situ nanosuspension: A novel approach towards the efficient administration of poorly soluble drugs at the anterior eye. European Journal of Pharmaceutical Sciences 50:3-4, pages 385-392.
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Marta Rodriguez-Aller, Davy Guillarme, Mohamed El Sanharawi, Francine Behar-Cohen, Jean-Luc Veuthey & Robert Gurny. (2013) In vivo distribution and ex vivo permeation of cyclosporine A prodrug aqueous formulations for ocular application. Journal of Controlled Release 170:1, pages 153-159.
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Chhavi Gupta, Anuj Chauhan & Sangly P. Srinivas. (2012) Penetration of Fluorescein Across the Rabbit Cornea from the Endothelial Surface. Pharmaceutical Research 29:12, pages 3325-3334.
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Burçin Yavuz, Sibel Bozdağ Pehlivan & Nurşen Ünlü. (2012) An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery. The Scientific World Journal 2012, pages 1-11.
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Thorsteinn Loftsson & Marcus E Brewster. (2011) Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes. Journal of Pharmacy and Pharmacology 63:9, pages 1119-1135.
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Alison Clode, Jennifer Davis, Gigi Davidson, Jacklyn Salmon, Heath Lafevers & Brian Gilger. (2011) Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes. Veterinary Ophthalmology 14:1, pages 41-47.
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Ali R. Djalilian, Arpita Kadakia Bhasin & Edward J. Holland. 2011. Cornea. Cornea 1745 1753 .
Uday B Kompella, Rajendra S Kadam & Vincent HL Lee. (2010) Recent advances in ophthalmic drug delivery. Therapeutic Delivery 1:3, pages 435-456.
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T. Loftsson & E. Stefánsson. (2007) Cyclodextrins in ocular drug delivery: theoretical basis with dexamethasone as a sample drug. Journal of Drug Delivery Science and Technology 17:1, pages 3-9.
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Frank A LattanzioJr.Jr., Earl R CrouchJr.Jr., Peter V Mitrev, Patricia B Williams & Robert C Allen. (2005) Cyclosporin as an Adjunct to Glaucoma Filtration Surgery. Journal of Glaucoma 14:6, pages 441-447.
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Earl R Crouch, Frank A Lattanzio, Patricia B Williams, Peter V Mitrev, Todd Theobald & Robert C Allen. (2004) Cyclosporin-Augmented Laser Peripheral Iridoplasty. Ophthalmic Surgery, Lasers and Imaging Retina 35:6, pages 475-481.
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F Lallemand, O Felt-Baeyens, K Besseghir, F Behar-Cohen & R Gurny. (2003) Cyclosporine A delivery to the eye: A pharmaceutical challenge. European Journal of Pharmaceutics and Biopharmaceutics 56:3, pages 307-318.
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Pieter van der Bijl, AH Engelbrecht, Armorél D. van Eyk & David Meyer. (2002) Comparative Permeability of Human and Rabbit Corneas to Cyclosporin and Tritiated Water. Journal of Ocular Pharmacology and Therapeutics 18:5, pages 419-427.
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Thorsteinn Loftsson & Einar Stefánsson. (2003) Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye. Acta Ophthalmologica Scandinavica 80:2, pages 144-150.
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Lixin Xie, Weiyun Shi, Zhiyu Wang, Jianzhong Bei & Shenguo Wang. (2001) Prolongation of Corneal Allograft Survival Using Cyclosporine in a Polylactide-co-glycolide Polymer. Cornea 20:7, pages 748-752.
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Thorsteinn Loftsson & Mar Masson. (2001) Cyclodextrins in topical drug formulations: theory and practice. International Journal of Pharmaceutics 225:1-2, pages 15-30.
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Pieter van der Bijl, Armorél D. van Eyk & David Meyer. (2001) Effects of Three Penetration Enhancers on Transcorneal Permeation of Cyclosporine. Cornea 20:5, pages 505-508.
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Chrystèle Le Bourlais, Liliane Acar, Hosein Zia, Pierre A. Sado, Thomas Needham & Roger Leverge. (1998) Ophthalmic drug delivery systems—Recent advances. Progress in Retinal and Eye Research 17:1, pages 33-58.
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Roger A. Rajewski & Valentino J. Stella. (1996) Pharmaceutical Applications of Cyclodextrins. 2. In Vivo Drug Delivery. Journal of Pharmaceutical Sciences 85:11, pages 1142-1169.
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Scott A. GruberAli R. Djalilian & Edward J. Holland. 1996. Local Immunosuppression of Organ Transplants. Local Immunosuppression of Organ Transplants 153 159 .
ANN T. GRATZEK, RENEE L. KASWAN, C. L. MARTIN, E. S. CHAMPAGNE & SUSAN L. WHITE. (2010) Ophthalmic cyclosporine in equine keratitis and keratouveitis: 11 cases. Equine Veterinary Journal 27:5, pages 327-333.
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Kristiina Järvinen, Tomi Järvinen & Arto Urtti. (1995) Ocular absorption following topical delivery. Advanced Drug Delivery Reviews 16:1, pages 3-19.
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Shawn L. Palmer, P. Allen BowenIIII & Keith Green. (1995) Tear Flow in Cyclosporine Recipients. Ophthalmology 102:1, pages 118-121.
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