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Journal of Asthma Volume 49, 2012 - Issue 3
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Mechanisms of Action

Peripheral Blood Gene Expression Changes during Allergen Inhalation Challenge in Atopic Asthmatic Individuals

Sarah H. Y. KamJames Hogg Research Centre, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada;Institute for HEART+LUNG Health, Vancouver, BC, Canada
, B.Mlsc.,
Amrit SinghJames Hogg Research Centre, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada;Institute for HEART+LUNG Health, Vancouver, BC, Canada
, B.Sc.,
Jian-Qing HeJames Hogg Research Centre, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada;Institute for HEART+LUNG Health, Vancouver, BC, Canada
, Ph.D.,
Jian RuanJames Hogg Research Centre, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada;Institute for HEART+LUNG Health, Vancouver, BC, Canada
, Ph.D.,
Gail M. GauvreauDepartment of Medicine, McMaster University, Hamilton, ON, Canada
, Ph.D.,
Paul M. O’ByrneDepartment of Medicine, McMaster University, Hamilton, ON, Canada
, M.D.,
J. Mark FitzgeraldInstitute for HEART+LUNG Health, Vancouver, BC, Canada;Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada;Vancouver Coastal Health Research Institute, Vancouver General Hospital, Vancouver, BC, Canada
, M.D. &
Scott J. TebbuttJames Hogg Research Centre, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada;Institute for HEART+LUNG Health, Vancouver, BC, Canada;Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, CanadaCorrespondence[email protected]
, Ph.D. show all
Pages 219-226 | Published online: 09 Feb 2012

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Defeng Zhang, Yuanbo Wu & Gengyun Sun. (2018) miR-192 suppresses T follicular helper cell differentiation by targeting CXCR5 in childhood asthma. Scandinavian Journal of Clinical and Laboratory Investigation 78:3, pages 236-242.
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Jean-Christophe Bérubé & Yohan Bossé. (2014) Future clinical implications emerging from recent genome-wide expression studies in asthma. Expert Review of Clinical Immunology 10:8, pages 985-1004.
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Jeanette M. Metzger, Mary S. Lopez, Jenna K. Schmidt, Megan E. Murphy, Raghu Vemuganti & Marina E. Emborg. (2020) Effects of Cardiac Sympathetic Neurodegeneration and PPAR γ Activation on Rhesus Macaque Whole Blood miRNA and mRNA Expression Profiles . BioMed Research International 2020, pages 1-13.
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Gema Mondejar-Parreño, María Callejo, Angel Cogolludo & Francisco Pérez-Vizcaíno. 2019. Nucleic Acid Nanotheranostics. Nucleic Acid Nanotheranostics 89 131 .
Karla Cervantes-Gracia & Holger Husi. (2018) Integrative analysis of Multiple Sclerosis using a systems biology approach. Scientific Reports 8:1.
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Núria Planell, M Carme Masamunt, Raquel Franco Leal, Lorena Rodríguez, Miriam Esteller, Juan J Lozano, Anna Ramírez, Maria de Lourdes Setsuko Ayrizono, Claudio Saddy Rodrigues Coy, Ignacio Alfaro, Ingrid Ordás, Sudha Visvanathan, Elena Ricart, Jordi Guardiola, Julián Panés & Azucena Salas. (2017) Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis. Journal of Crohn's and Colitis 11:11, pages 1335-1346.
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John F. Bowyer, Karen M. Tranter, Joseph P. Hanig, Nathaniel M. Crabtree, Robert P. Schleimer & Nysia I. George. (2015) Evaluating the Stability of RNA-Seq Transcriptome Profiles and Drug-Induced Immune-Related Expression Changes in Whole Blood. PLOS ONE 10:7, pages e0133315.
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Darawan Rinchai, Scott Presnell, Marta Vidal, Sheetij Dutta, Virander Chauhan, David Cavanagh, Gemma Moncunill, Carlota Dobaño & Damien Chaussabel. (2017) Blood Interferon Signatures Putatively Link Lack of Protection Conferred by the RTS,S Recombinant Malaria Vaccine to an Antigen-specific IgE Response. F1000Research 4, pages 919.
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Young Woong Kim, Amrit Singh, Casey P Shannon, Gail M Gauvreau & Scott J Tebbutt. (2014) Transcriptional networks in whole blood of asthmatics. Allergy, Asthma & Clinical Immunology 10:S2.
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Amrit Singh, Masatsugu Yamamoto, Jian Ruan, Jung Young Choi, Gail M Gauvreau, Sven Olek, Ulrich Hoffmueller, Christopher Carlsten, J Mark FitzGerald, Louis-Philippe Boulet, Paul M O'Byrne & Scott J Tebbutt. (2014) Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response. Allergy, Asthma & Clinical Immunology 10:1.
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Jeremy A. Hirota, Neil E. Alexis, Mandy Pui, SzeWing Wong, Elkie Fung, Phillip Hansbro, Darryl A. Knight, Don D. Sin & Chris Carlsten. (2014) PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: Application of an in vitro model system exposing dendritic cells to airway epithelial cell-conditioned media . Respirology 19:6, pages 881-890.
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Heesun Shin, Casey P. Shannon, Nick Fishbane, Jian Ruan, Mi Zhou, Robert Balshaw, Janet E. Wilson-McManus, Raymond T. Ng, Bruce M. McManus & Scott J. Tebbutt. (2014) Variation in RNA-Seq Transcriptome Profiles of Peripheral Whole Blood from Healthy Individuals with and without Globin Depletion. PLoS ONE 9:3, pages e91041.
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Amrit Singh, Masatsugu Yamamoto, Sarah H. Y. Kam, Jian Ruan, Gail M. Gauvreau, Paul M. O'Byrne, J. Mark FitzGerald, Robert Schellenberg, Louis-Philippe Boulet, Gabriella Wojewodka, Cynthia Kanagaratham, Juan B. De Sanctis, Danuta Radzioch & Scott J. Tebbutt. (2013) Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses. PLoS ONE 8:7, pages e67907.
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Masatsugu Yamamoto, Amrit Singh, Jian Ruan, Gail M Gauvreau, Paul M O'Byrne, Christopher R Carlsten, J Mark FitzGerald, Louis-Philippe Boulet & Scott J Tebbutt. (2012) Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge. BMC Genomics 13:1.
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Amrit Singh, Gabriela V. Cohen Freue, Jean L. Oosthuizen, Sarah H. Y. Kam, Jian Ruan, Mandeep K. Takhar, Gail M. Gauvreau, Paul M. O'Byrne, J. Mark FitzGerald, Louis‐Philippe Boulet, Christoph H. Borchers & Scott J. Tebbutt. (2012) Plasma proteomics can discriminate isolated early from dual responses in asthmatic individuals undergoing an allergen inhalation challenge. PROTEOMICS – Clinical Applications 6:9-10, pages 476-485.
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