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Journal of Asthma Volume 49, 2012 - Issue 7
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Genetic Determinants

Evaluation of a Common Variant of the Gene Encoding Clara Cell 10 kd Protein (CC10) as a Candidate Determinant for Asthma Severity and Steroid Responsiveness Among Chinese Children

Li-Chen ChenThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
, M.D.,
Hsu-Min TsengDepartment of Healthcare Management, Chang Gung University, Taoyuan, Taiwan
, PH.D.,
Chia-Jen WuDepartment of Microbiology and Immunology, Graduate Institute of Basic Medical Research, Chang Gung University, Taoyuan, Taiwan
, M.S.,
Ming-Ling KuoDepartment of Microbiology and Immunology, Graduate Institute of Basic Medical Research, Chang Gung University, Taoyuan, Taiwan
, PH.D.,
Cheng-Jang WuDepartment of Microbiology and Immunology, Graduate Institute of Basic Medical Research, Chang Gung University, Taoyuan, Taiwan
, M.S.,
Pei-Song GaoJohns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
, M.D., PH.D.,
Kuo-Wei YehThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
, M.D.,
Tsung-Chieh YaoThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
, M.D., PH.D.,
Wen-I LeeThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
, M.D., PH.D.,
Liang-Shiou OuThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan
, M.D.,
Jing-Long HuangThe Division of Allergy, Asthma and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, TaiwanCorrespondence[email protected] [email protected]
, M.D. &
Shau-Ku HuangJohns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA;National Health Research Institutes, Miaoli, TaiwanCorrespondence[email protected] [email protected]
, PH.D. show all
Pages 665-672 | Published online: 13 Jul 2012

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Menolly Lee, Yulia Bogdanova, Mei Chan, Louisa Owens, Sandy Wales, Melinda Gray, Christine Burns, Nancy Briggs, Adam Jaffe & Nusrat Homaira. (2022) Development and validation of a risk score to identify children at risk of life-threatening asthma. Journal of Asthma 59:1, pages 105-114.
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Articles from other publishers (13)

Tereza Martinu, Jamie L. Todd, Andrew E. Gelman, Stefano Guerra & Scott M. Palmer. (2023) Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics. Annual Review of Medicine 74:1, pages 427-441.
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Houman Goudarzi, Hirokazu Kimura, Hiroki Kimura, Hironi Makita, Michiko Takimoto-Sato, Yuki Abe, Akira Oguma, Munehiro Matsumoto, Nozomu Takei, Machiko Matsumoto-Sasaki, Kaoruko Shimizu, Masaru Suzuki, Noriharu Shijubo, Shau-ku Huang, Nobuyuki Hizawa, Masaharu Nishimura & Satoshi Konno. (2023) Association of serum CC16 levels with eosinophilic inflammation and respiratory dysfunction in severe asthma. Respiratory Medicine 206, pages 107089.
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Sarah J.D. Nauwelaerts, Nina Van Goethem, Koen De Cremer, Natalia Bustos Sierra, Jordy Vercauteren, Christophe Stroobants, Alfred Bernard, Tim Nawrot, Nancy H.C. Roosens & Sigrid C.J. De Keersmaecker. (2023) Noninvasive integrative approach applied to children in the context of recent air pollution exposure demonstrates association between fractional exhaled nitric oxide (FeNO) and urinary CC16. Environmental Research 216, pages 114441.
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Houman Goudarzi, Hirokazu Kimura, Hiroki Kimura, Hironi Makita, Munehiro Matsumoto, Nozomu Takei, Kaoruko Shimizu, Masaru Suzuki, Taku Watanabe, Eiki Kikuchi, Hiroshi Ohira, Ichizo Tsujino, Jun Sakakibara-Konishi, Naofumi Shinagawa, Noriharu Shijubo, Hirokazu Sato, Katsunori Shigehara, Kichizo Kaga, Yasuhiro Hida, Soichi Murakami, Yuma Ebihara, Akinobu Nakamura, Hideaki Miyoshi, Satoshi Hirano, Nobuyuki Hizawa, Tatsuya Atsumi, Shau-ku Huang, Yoichi M. Ito, Masaharu Nishimura & Satoshi Konno. (2022) Effects of obesity on CC16 and their potential role in overweight/obese asthma. Respiratory Research 23:1.
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Sarah J.D. Nauwelaerts, Nina Van Goethem, Berta Tenas Ureña, Koen De Cremer, Alfred Bernard, Nelly D. Saenen, Tim S. Nawrot, Nancy H.C. Roosens & Sigrid C.J. De Keersmaecker. (2022) Urinary CC16, a potential indicator of lung integrity and inflammation, increases in children after short-term exposure to PM2.5/PM10 and is driven by the CC16 38GG genotype. Environmental Research 212, pages 113272.
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Sarah J. D. Nauwelaerts, Koen De Cremer, Natalia Bustos Sierra, Mathieu Gand, Dirk Van Geel, Maud Delvoye, Els Vandermassen, Jordy Vercauteren, Christophe Stroobants, Alfred Bernard, Nelly D. Saenen, Tim S. Nawrot, Nancy H. C. Roosens & Sigrid C. J. De Keersmaecker. (2022) Assessment of the Feasibility of a Future Integrated Larger-Scale Epidemiological Study to Evaluate Health Risks of Air Pollution Episodes in Children. International Journal of Environmental Research and Public Health 19:14, pages 8531.
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Martine Mootz, Constanze A. Jakwerth, Carsten B. Schmidt‐Weber & Ulrich M. Zissler. (2021) Secretoglobins in the big picture of immunoregulation in airway diseases. Allergy 77:3, pages 767-777.
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Klaus Bønnelykke, Gerard H. Koppelman, Elise M. A. Slob, Susanne J. H. Vijverberg & Anke H. Maitland-van der Zee. 2020. Severe Asthma in Children and Adolescents. Severe Asthma in Children and Adolescents 313 341 .
Esther Herrera-Luis, Natalia Hernandez-Pacheco, Susanne J. Vijverberg, Carlos Flores & Maria Pino-Yanes. (2019) Role of genomics in asthma exacerbations. Current Opinion in Pulmonary Medicine 25:1, pages 101-112.
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J.A. Castro-Rodriguez, I. Atton, G. Villarroel & C.A. Serrano. (2018) Relation between serum CC16 levels and asthma predictive index in pre-schoolers with recurrent wheezing. Allergologia et Immunopathologia 46:5, pages 460-466.
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Lin-Shien Fu & Ming-Chin Tsai. (2014) Asthma Exacerbation in Children: A Practical Review. Pediatrics & Neonatology 55:2, pages 83-91.
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Hyeon-Jong YangBong-Seong KimWoo Kyung KimJakyoung KimJin Tack KimDong In SuhYoung Yull KohYoun Ho ShinSo-Yeon LeeDae Hyun LimJi Tae ChoungHyo-Bin Kim. (2014) Phenotype and endotype in pediatric asthma. Allergy, Asthma & Respiratory Disease 2:2, pages 85.
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Wei Nie, Cheng Xue, Jiquan Chen & Qingyu Xiu. (2013) Secretoglobin 1A member 1 (SCGB1A1) +38A/G polymorphism is associated with asthma risk: A meta-analysis. Gene 528:2, pages 304-308.
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