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Journal of Asthma Volume 25, 1988 - Issue 3
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Original Article

Thromboxane A2 Production in Allergen-Induced Immediate and Late Asthmatic Responses: Its Possible Role in Inducing the Late Response

I. Iwamoto Second Department of Internal Medicine Chiba, University School of Medicine, 1–8-1 Inohana Chiba City, Chiba, 280, Japan
,
C. Ra Second Department of Internal Medicine Chiba, University School of Medicine, 1–8-1 Inohana Chiba City, Chiba, 280, Japan
,
T. Sato Second Department of Internal Medicine Chiba, University School of Medicine, 1–8-1 Inohana Chiba City, Chiba, 280, Japan
,
H. Tomioka Second Department of Internal Medicine Chiba, University School of Medicine, 1–8-1 Inohana Chiba City, Chiba, 280, Japan
&
S. Yoshida Second Department of Internal Medicine Chiba, University School of Medicine, 1–8-1 Inohana Chiba City, Chiba, 280, Japan
Pages 117-124 | Published online: 02 Jul 2009

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Bernard Masereel, Jean-Michel Dogné, Jacques Delarge & Xavier de Leval. (2001) Recent developments of thromboxane modulators. Expert Opinion on Therapeutic Patents 11:11, pages 1663-1675.
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Articles from other publishers (30)

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Noemí Vila, Pedro Besada, Tamara Costas, Mª Carmen Costas-Lago & Carmen Terán. (2015) Phthalazin-1(2H)-one as a remarkable scaffold in drug discovery. European Journal of Medicinal Chemistry 97, pages 462-482.
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Ying Lei, Yongxiao Cao, Yaping Zhang, Lars Edvinsson & Cang-Bao Xu. (2011) Enhanced airway smooth muscle cell thromboxane receptor signaling via activation of JNK MAPK and extracellular calcium influx. European Journal of Pharmacology 650:2-3, pages 629-638.
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Cang‐Bao Xu, Ying Lei, Qingwen Chen, Christina Pehrson, Lennart Larsson & Lars Edvinsson. (2010) Cigarette Smoke Extracts Promote Vascular Smooth Muscle Cell Proliferation and Enhances Contractile Responses in the Vasculature and Airway. Basic & Clinical Pharmacology & Toxicology 107:6, pages 940-948.
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Alicja Kasperska-Zajac & Barbara Rogala. (2007) Platelet Activation During Allergic Inflammation. Inflammation 30:5, pages 161-166.
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Hiroshi Marusawa, Hiroyuki Setoi, Akihiko Sawada, Akio Kuroda, Jiro Seki, Yukio Motoyama & Hirokazu Tanaka. (2002) Synthesis and Biological Activity of 1-Phenylsulfonyl-4-Phenylsulfonylaminopyrrolidine Derivatives as Thromboxane A 2 Receptor Antagonists. Bioorganic & Medicinal Chemistry 10:5, pages 1399-1415.
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Akinori Mochizuki, Norihiko Tamura, Yoriko Yatabe, Sadayoshi Onodera, Toru Hiruma, Niro Inaba, Jun Kusunoki & Hisao Tomioka. (2001) Suppressive effects of F-1322 on the antigen-induced late asthmatic response and pulmonary eosinophilia in guinea pigs. European Journal of Pharmacology 430:1, pages 123-133.
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MASAKI FUJIMURA, MIKI ABO, YUMIE KAMIO, SHIGEHARU MYOU, YOSHIHISA ISHIURA, TAKUMA HASHIMOTO & TAMOTSU MATSUDA. (1999) Effect of Leukotriene and Thromboxane Antagonist on Propranolol-induced Bronchoconstriction. American Journal of Respiratory and Critical Care Medicine 160:6, pages 2100-2103.
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R.M. Hegde & L.I.G. Worthley. (1999) Acute Asthma and the Life Threatening Episode. Critical Care and Resuscitation 1:4, pages 371-387.
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Mitsutaka Takami & Wataru Tsukada. (1999) Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents. European Journal of Pharmacology 366:2-3, pages 253-259.
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M. Takami & W. Tsukada. (1998) Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs. Prostaglandins, Leukotrienes and Essential Fatty Acids 59:6, pages 407-414.
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Chizu Fukushima, Terufumi Shimoda, Hiroto Matsuse, Nobuko Matsuo, Atsuko Takao, Yasusi Obase, Shigeru Kohno & Sadahiro Asai. (1998) Effect of Synthetase Inhibitors and Receptor Antagonists in Antigen-Induced Contraction of Human Lung Parenchyma. Annals of Allergy, Asthma & Immunology 80:3, pages 245-250.
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Hiroshi Takeda, Akifumi Kogame, Hiroyuki Tanaka & Hiroichi Nagai. (1997) Time Course Study for Airway Inflammation and Responsiveness by Repeated Provocation of Aeroantigen in Guinea Pigs. Prostaglandins 54:5, pages 805-820.
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Toshiaki Ishizuka. (2007) DP‐1904: A Novel Specific TXA 2 Synthetase Inhibitor . Cardiovascular Drug Reviews 15:1, pages 27-43.
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Chizu Fukushima, Terufumi Shimoda, Hiroto Matsuse, Atsuko Takao, Hiroyuki Sakai, Shigeru Kohno, Kohei Hara & Sadahiro Asai. (1996) Inhibitory Effect of Thromboxane A2 Synthetase Inhibitor, DP-1904, on Antigen-Induced Contraction of Human Lung Parenchyma. Annals of Allergy, Asthma & Immunology 77:6, pages 483-487.
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Takeshi Ohtsuka, Shinichi Matsumaru, Keiji Uchida, Makoto Onobori, Tsutomu Matsumoto, Keiko Kuwahata & Masahiko Arita. (1996) Pathogenic Role of Thromboxane A2 in Immediate Food Hypersensitivity Reactions in Children. Annals of Allergy, Asthma & Immunology 77:1, pages 55-59.
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H. Nagai, H. Kawasaki, H. Takeda, Y. Takaoka & N. Inagaki. (1995) The effect of a TXA2 receptor antagonist ON-579 on experimental allergic reactions. Prostaglandins, Leukotrienes and Essential Fatty Acids 53:2, pages 123-133.
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Hiroichi Nagai, Hiroshi Takeda, Shuuji Yamaguchi, Hiroyuki Tanaka, Akihiko Matsuo & Naoki Inagaki. (1995) The effect of a thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions. Prostaglandins 50:2, pages 75-87.
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Motoyasu Saito, Masaki Fujimura, Haruhiko Ogawa & Tamotsu Matsuda. (1995) Role of thromboxane A2 and platelet-activating factor in allergic bronchoconstriction in guinea pig airway in vivo. Journal of Lipid Mediators and Cell Signalling 11:1, pages 1-12.
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Phillip J. Gardiner. 1995. Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction. Airways Smooth Muscle: Neurotransmitters, Amines, Lipid Mediators and Signal Transduction 181 198 .
M. Saito, M. Fujimura, K. Mizuhashi, H. Shintani & T. Matsuda. (1994) Effects of aerosol administration of a thromboxane receptor antagonist (S-1452) on experimental asthma in guinea pigs. Allergy 49:8, pages 680-684.
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T. Obata, N. Yamashita & T. Nakagawa. (1994) Leukotriene and thromboxane antagonists. Clinical Reviews in Allergy 12:1, pages 79-93.
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D.W.P. Hay & D.E. Griswold. 1994. Lipid Mediators. Lipid Mediators 117 179 .
Paul A. J. Henricks, Betty Van Esch, Ferdi Engels & Frans P. Nijkamp. (1993) Effects of parainfluenza type 3 virus on guinea pig pulmonary alveolar macrophage functions in vitro. Inflammation 17:6, pages 663-675.
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Kazuhiro Itoh, Yumiko Satoh, Marie Hisamoto, Naotoshi Yamamura, Osamu Mukaiyama, Takeshi Yamaguchi, Toshihiko Ikeda & Keiichi Matsuda. (1993) Alteration of eicosanoid production in the sensitized guinea pig lung by CS-518. European Journal of Pharmacology 237:2-3, pages 215-221.
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Takeshi Yamaguchi, Osamu Mukaiyama, Kazuhiro Itoh, Yumiko Satoh, Atsusuke Terada & Yoshio Iizuka. (1993) Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response. European Journal of Pharmacology 236:1, pages 43-50.
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V A Alabaster & B A Moore. (1993) New perspectives on basic mechanisms in lung disease. 3. Drug intervention in asthma: present and future.. Thorax 48:2, pages 176-182.
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Hitoshi Arita, Atsushi Kurosawa, Takayoshi Oguma, Tadahisa Kitamura, Akio Ebihara & Masayuki Narisada. (2007) S‐1452—A Novel TXA 2 Receptor Antagonist . Cardiovascular Drug Reviews 10:3, pages 280-295.
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G. Lueddeckens, K. Becker, R. Rappold & W. Förster. (1991) Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2107 and BN 52021 on Endothelin-1 induced vaso- and bronchoconstriction. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 44:3, pages 155-158.
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M. TAKAMI, Y. TAKATA, K. MATSUMOTO, S. ONO & W. TSUKADA. (1991) Effect of DP-1904, a New Thromboxane A 2 Synthetase Inhibitor, on Guinea Pig Experimental Asthma . Annals of the New York Academy of Sciences 629:1 Advances in t, pages 407-409.
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