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Research Article

Incidence, epidemiology and treatment results of osteosarcoma in Finland – a nationwide population-based study

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Pages 1206-1214 | Received 20 Jun 2011, Accepted 12 Aug 2011, Published online: 24 Oct 2011

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Kjetil Berner, Olga Zaikova, Tom Børge Johannesen, Kirsten Sundby Hall & Øyvind S. Bruland. (2018) Validity and completeness of the Scandinavian Sarcoma Group Central Register by comparison with a nationwide cohort of patients with osteosarcoma in Norway. Journal of Surgical Oncology 118:1, pages 246-247.
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James Coventon. (2017) A review of the mechanism of action and clinical applications of sorafenib in advanced osteosarcoma. Journal of Bone Oncology 8, pages 4-7.
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Chuanzhen Hu, Xu Chen, Junxiang Wen, Liangzhi Gong, Zhuochao Liu, Jun Wang, Jing Liang, Fangqiong Hu, Qi Zhou, Li Wei, Yuhui Shen & Weibin Zhang. (2017) Antitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivo . Cancer Science 108:7, pages 1347-1356.
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Crossref
Yong Wang, Tao Yang, Zhen Zhang, Ming Lu, Wei Zhao, Xiandong Zeng & Weiguo Zhang. (2017) Long non‐coding RNA TUG 1 promotes migration and invasion by acting as a ce RNA of miR‐335‐5p in osteosarcoma cells . Cancer Science 108:5, pages 859-867.
Crossref
Xiaolong Yu, Qiang Wang, Xin Zhou, Changlin Fu, Ming Cheng, Runsheng Guo, Hucheng Liu, Bin Zhang & Min Dai. (2016) Celastrol negatively regulates cell invasion and migration ability of human osteosarcoma via downregulation of the PI3K/Akt/NF-κB signaling pathway in vitro. Oncology Letters 12:5, pages 3423-3428.
Crossref
Quan Zhou, Fengli Chen, Zhongting Fei, Jiali Zhao, Yong Liang, Wei Pan, Xingxiang Liu & Donghui Zheng. (2016) Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma. Oncotarget 7:15, pages 19928-19934.
Crossref
Olga Zaikova, Kirsten Sundby Hall, Emelie Styring, Mikael Eriksson, Clement S. Trovik, Peter Bergh, Bodil Bjerkehagen, Mikael Skorpil, Harald Weedon-Fekjaer & Henrik C.F. Bauer. (2015) Referral patterns, treatment and outcome of high-grade malignant bone sarcoma in Scandinavia-SSG Central Register 25 years' experience. Journal of Surgical Oncology 112:8, pages 853-860.
Crossref
Ke Ren, Xiao Lu, Nan Yao, Yong Chen, Aizhen Yang, Hui Chen, Jian Zhang, Sujia Wu, Xin Shi, Chen Wang & Xiaoliang Sun. (2015) Focal adhesion kinase overexpression and its impact on human osteosarcoma. Oncotarget 6:31, pages 31085-31103.
Crossref
Joni Serlo, Maija Tarkkanen, Mika Sampo, Kim Vettenranta, Pekka Riikonen & Ilkka Helenius. (2015) Incidence, treatment and survival of paediatric patients with bone sarcomas in Finland from 1991 to 2005. Acta Paediatrica 104:7, pages 738-745.
Crossref
Kjetil Berner, Tom Børge Johannesen & Øyvind S. Bruland. (2015) Clinical Epidemiology of Low-Grade and Dedifferentiated Osteosarcoma in Norway during 1975 and 2009. Sarcoma 2015, pages 1-9.
Crossref
Kjetil Berner, Kirsten Sundby Hall, Odd R. Monge, Harald Weedon-Fekjær, Olga Zaikova & Øyvind S. Bruland. (2015) Prognostic Factors and Treatment Results of High-Grade Osteosarcoma in Norway: A Scope Beyond the “Classical” Patient. Sarcoma 2015, pages 1-14.
Crossref
I. Kushnir, Y. Kolander, J. Bickels, Y. Gortzak, G. Flusser, J. Issakov & O. Merimsky. (2014) Is it important to maintain high-dose intensity chemotherapy in the treatment of adults with osteosarcoma?. Medical Oncology 31:5.
Crossref
N.O. Basta, P.W. James, B. Gomez-Pozo, A.W. Craft, P. Norman & R.J.Q. McNally. (2014) Survival from teenage and young adult cancer in Northern England, 1968-2008. Pediatric Blood & Cancer 61:5, pages 901-906.
Crossref
Mehmet Metin Seker, Ayse Seker, Sercan Aksoy, Nuriye Ozdemir, Dogan Uncu & Nurullah Zengin. (2014) Clinicopathologic Features and Prognosis of Osteosarcoma in Turkish Adults. Asian Pacific Journal of Cancer Prevention 15:8, pages 3537-3540.
Crossref
Patrick W. O’Donnell, Anthony M. Griffin, William C. Eward, Amir Sternheim, Jay S. Wunder & Peter C. Ferguson. (2013) Early follow-up of a custom non-fluted diaphyseal press-fit tumour prosthesis. International Orthopaedics 38:1, pages 123-127.
Crossref
Rozalia Dimitriou, George I Mataliotakis, Giorgio Maria Calori & Peter V Giannoudis. (2012) The role of barrier membranes for guided bone regeneration and restoration of large bone defects: current experimental and clinical evidence. BMC Medicine 10:1.
Crossref

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