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Acta Oncologica Volume 53, 2014 - Issue 10
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Renal cell cancer

Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib

Benoit BeuselinckDepartment of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium;Inserm U674 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, FranceCorrespondence[email protected]
,
Diether LambrechtsLaboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium;Vesalius Research Center, VIB, Leuven, Belgium
,
Thomas Van BrusselLaboratory for Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium;Vesalius Research Center, VIB, Leuven, Belgium
,
Pascal WolterDepartment of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium
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Nina CardinaelsDepartment of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium
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Steven JoniauDepartment of Urology, University Hospitals Leuven, KU Leuven, Leuven, Belgium
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Evelyne LerutDepartment of Pathology, University Hospitals Leuven, KU Leuven, Leuven, Belgium
,
Alexandra KaradimouInserm U674 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, France
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Gabrielle CouchyInserm U674 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, France
,
Philippe SebeDepartment of Urology, Hôpital des Diaconesses, Paris, France
,
Alain RavaudDepartment of Medical Oncology, University Hospital of Bordeaux and University Victor Segalen, Talence, Bordeaux, France
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Marc ZerbibDepartment of Urology, Hôpital Cochin, Paris, France
,
Armelle CatyDepartment of Medical Oncology, Centre Oscar Lambret, Lille, France
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Robert ParidaensDepartment of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium
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Patrick SchöffskiDepartment of General Medical Oncology and Laboratory for Experimental Oncology, University Hospitals Leuven, Leuven Cancer Institute, KU Leuven, Leuven, Belgium
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Virginie VerkarreDepartment of Pathology, Hôpital Necker Enfants Malades, Université Paris-5 René Descartes, Paris, France
,
Julien BergerDepartment of Urology, Hôpital Dupuytren, Limoges, France
,
Jean-Jacques PatardDepartment of Urology, Hôpital Bicêtre, Le Kremlin Bicêtre, France
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Jessica Zucman-RossiInserm U674 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, France;Department of Medical Oncology, Georges Pompidou European Hospital, Université Paris-5 René Descartes, Paris, France
&
Stéphane OudardInserm U674 Génomique Fonctionnelle des Tumeurs Solides, Université Paris-5 René Descartes, Paris, France;Department of Medical Oncology, Georges Pompidou European Hospital, Université Paris-5 René Descartes, Paris, France
 show all
Pages 1413-1422 | Received 04 Jul 2013, Accepted 04 Apr 2014, Published online: 30 May 2014

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Da-Qing Tan. (2020) Influence of ABCB1 (1236C > T, 2677G > T and 3435C > T) polymorphisms on the transport ability of P-gp-mediated sunitinib in Caco-2 cell line. Xenobiotica 50:3, pages 346-353.
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Meta H. M. Diekstra, Jesse J. Swen, Hans Gelderblom & Henk-Jan Guchelaar. (2016) A decade of pharmacogenomics research on tyrosine kinase inhibitors in metastatic renal cell cancer: a systematic review. Expert Review of Molecular Diagnostics 16:5, pages 605-618.
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