Citations (47)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Aditya Kiran Gatta, Raghu Chandrashekhar Hariharapura, Nayanabhirama Udupa, Meka Sreenivasa Reddy & Venkata Rao Josyula. (2018) Strategies for improving the specificity of siRNAs for enhanced therapeutic potential. Expert Opinion on Drug Discovery 13:8, pages 709-725.
Read now
Read now
Bo Yang, Chen Dai, Rumeng Tan, Bo Zhang, Xiao Meng, Jing Ye, Xinqiang Wang, Lai Wei, Fan He & Zhishui Chen. (2016) Lrig1 is a positive prognostic marker in hepatocellular carcinoma. OncoTargets and Therapy 9, pages 7071-7079.
Read now
Read now
Malin Lando, Christina S Fjeldbo, Saskia M Wilting, Barbara C Snoek, Eva-Katrine Aarnes, Malin F Forsberg, Gunnar B Kristensen, Renske DM Steenbergen & Heidi Lyng. (2015) Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer. Epigenetics 10:10, pages 970-980.
Read now
Read now
Samuel Kvarnbrink, Terese Karlsson, Karolina Edlund, Johan Botling, David Lindquist, Karin Jirström, Patrick Micke, Roger Henriksson, Mikael Johansson & Håkan Hedman. (2015) LRIG1 is a prognostic biomarker in non-small cell lung cancer. Acta Oncologica 54:8, pages 1113-1119.
Read now
Read now
Articles from other publishers (43)
Brittany D. Jenkins, Emily Rossi, Catherine Pichardo, William Wooten, Margaret Pichardo, Wei Tang, Tiffany H. Dorsey, Anuoluwapo Ajao, Ruby Hutchison, Leah Moubadder, Lauren E. McCullough, Maeve Bailey-Whyte & Stefan Ambs. (2023) Neighborhood Deprivation and DNA Methylation and Expression of Cancer Genes in Breast Tumors. JAMA Network Open 6:11, pages e2341651.
Crossref
Crossref
Yingchen Qian, Xiaoxue Li, Jin Qiu & Runjie Zhang. (2022) Insulin-induced gene 2 expression is associated with cervical adenocarcinoma malignant behavior. Molecular Biology Reports 50:2, pages 1553-1563.
Crossref
Crossref
Chen Xue, Ganglei Li, Qiuxian Zheng, Xinyu Gu, Zhengyi Bao, Juan Lu & Lanjuan Li. (2022) The functional roles of the circRNA/Wnt axis in cancer. Molecular Cancer 21:1.
Crossref
Crossref
Kirsty M. Ferguson, Carla Blin, Neza Alfazema, Ester Gangoso, Steven M. Pollard & Maria Angeles Marques-Torrejon. (2022) Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Maxine Umeh-Garcia, Henriette O’Geen, Catalina Simion, Melanie Hayden Gephart, David J. Segal & Colleen A. Sweeney. (2022) Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer. British Journal of Cancer 127:3, pages 436-448.
Crossref
Crossref
Qiudan Zhang, Chenming Zhong, Jinze Shen, Sang Chen, Yunhua Jia & Shiwei Duan. (2022) Emerging role of LINC00461 in cancer. Biomedicine & Pharmacotherapy 152, pages 113239.
Crossref
Crossref
Laura Succony, Sandra Gómez-López, Adam Pennycuick, Ahmed S.N. Alhendi, Derek Davies, Sarah E. Clarke, Kate H.C. Gowers, Nicholas A. Wright, Kim B. Jensen & Sam M. Janes. (2022)
Lrig1
expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth
. European Respiratory Journal 59:3, pages 2000816.
Crossref
Crossref
Yulica Santos-Ortega & Nabil Killiny. (2021) The Chorion Proteome of Diaphorina citri, the Vector of Huanglongbing Disease in Citrus. Insects 12:11, pages 959.
Crossref
Crossref
Christine Hoesl, Thomas Fröhlich, Christian Posch, Hermann Kneitz, Matthias Goebeler, Marlon R. Schneider & Maik Dahlhoff. (2021) The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis. Molecular Oncology 15:8, pages 2140-2155.
Crossref
Crossref
Jing Guo, Xuxian Zhong, Qinglin Tan, Shengnan Yang, Jiaqi Liao, Jinke Zhuge, Ziyang Hong, Qiong Deng & Qiang Zuo. (2021) miR-301a-3p induced by endoplasmic reticulum stress mediates the occurrence and transmission of trastuzumab resistance in HER2-positive gastric cancer. Cell Death & Disease 12:7.
Crossref
Crossref
Ola Billing, Ylva Holmgren, Daniel Nosek, Håkan Hedman & Oskar Hemmingsson. (2021) LRIG1 is a conserved EGFR regulator involved in melanoma development, survival and treatment resistance. Oncogene 40:21, pages 3707-3718.
Crossref
Crossref
Chenghao Peng, Hanmin Chen, Youwei Li, Hang Yang, Peizhong Qin, Baojun Ma, Qiuhong Duan, Baofeng Wang, Feng Mao & Dongsheng Guo. (2021) LRIG3 Suppresses Angiogenesis by Regulating the PI3K/AKT/VEGFA Signaling Pathway in Glioma. Frontiers in Oncology 11.
Crossref
Crossref
Carl Herdenberg, Pascal M. Mutie, Ola Billing, Ahmad Abdullah, Rona J. Strawbridge, Ingrid Dahlman, Simon Tuck, Camilla Holmlund, Peter Arner, Roger Henriksson, Paul W. Franks & Håkan Hedman. (2021) LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes. Communications Biology 4:1.
Crossref
Crossref
Mahmood Faraz, Andreas Tellström, Christina Edwinsdotter Ardnor, Kjell Grankvist, Lukasz Huminiecki, Björn Tavelin, Roger Henriksson, Håkan Hedman & Ingrid Ljuslinder. (2020) LRIG1 gene copy number analysis by ddPCR and correlations to clinical factors in breast cancer. BMC Cancer 20:1.
Crossref
Crossref
Kiran Busayavalasa, Mario Ruiz, Ranjan Devkota, Marcus Ståhlman, Rakesh Bodhicharla, Emma Svensk, Nils-Olov Hermansson, Jan Borén & Marc Pilon. (2020) Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins. PLOS Genetics 16:8, pages e1008975.
Crossref
Crossref
Kaixuan Zeng, Xiaoxiang Chen, Mu Xu, Xiangxiang Liu, Chenmeng Li, Xueni Xu, Bei Pan, Jian Qin, Bangshun He, Yuqin Pan, Sun Huiling, Tao Xu & Shukui Wang. (2020) LRIG3 represses cell motility by inhibiting slug via inactivating ERK signaling in human colorectal cancer. IUBMB Life 72:7, pages 1393-1403.
Crossref
Crossref
Shirin Salehizadeh, Mandana Hasanzad, Azade Amini Kadijani & Abolfazl Akbari. (2019) The Expression Analysis of Intestinal Cancer Stem Cell Marker Lgr5 in Colorectal Cancer Patients and the Correlation with Histopathological Markers. Journal of Gastrointestinal Cancer 51:2, pages 591-599.
Crossref
Crossref
Satoshi Iino, Kazuhide Horiguchi & Satomi Horiguchi. (2020) Investigation of Novel c-Kit-expressing Smooth Muscle Cells in Murine Cecum. ACTA HISTOCHEMICA ET CYTOCHEMICA 53:2, pages 11-19.
Crossref
Crossref
Tao Tao, Simin Yuan, Jinjian Liu, Da Shi, Mian Peng, Chong Li & Song Wu. (2020) Cancer stem cell-specific expression profiles reveal emerging bladder cancer biomarkers and identify circRNA_103809 as an important regulator in bladder cancer. Aging 12:4, pages 3354-3370.
Crossref
Crossref
Neil A. Roberts & Adrian S. Woolf. 2020. Heparanase. Heparanase
807
819
.
Qiuhui Li, Bigang Liu, Hsueh-Ping Chao, Yibing Ji, Yue Lu, Rashid Mehmood, Collene Jeter, Taiping Chen, John R. Moore, Wenqian Li, Can Liu, Kiera Rycaj, Amanda Tracz, Jason Kirk, Tammy Calhoun-Davis, Jie Xiong, Qu Deng, Jiaoti Huang, Barbara A. Foster, Abhiram Gokhale, Xin Chen & Dean G. Tang. (2019) LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer. Nature Communications 10:1.
Crossref
Crossref
Christine Hoesl, Thomas Fröhlich, Jennifer E. Hundt, Hermann Kneitz, Matthias Goebeler, Ronald Wolf, Marlon R. Schneider & Maik Dahlhoff. (2019) The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis. Molecular Oncology 13:11, pages 2476-2492.
Crossref
Crossref
Zhong‐zheng Xiang, Fang Liu, Ruo‐nan Yan, Yuan‐yuan Zeng, Tao He, Zhen Zeng, Zhi‐hui Zhu, Long Bai, Jia‐chun Ma & Lei Liu. (2019) The prognostic value of volumetric reduction of the target lesions after induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma. Head & Neck 41:6, pages 1863-1872.
Crossref
Crossref
Virginie Neirinckx, Ann-Christin Hau, Anne Schuster, Sabrina Fritah, Katja Tiemann, Eliane Klein, Petr V Nazarov, André Matagne, Martyna Szpakowska, Max Meyrath, Andy Chevigné, Mirko H H Schmidt & Simone P Niclou. (2019) The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein–protein interaction in glioblastoma. Neuro-Oncology Advances 1:1.
Crossref
Crossref
Neil A. Roberts, Emma N. Hilton, Filipa M. Lopes, Subir Singh, Michael J. Randles, Natalie J. Gardiner, Karl Chopra, Riccardo Coletta, Zunera Bajwa, Robert J. Hall, Wyatt W. Yue, Franz Schaefer, Stefanie Weber, Roger Henriksson, Helen M. Stuart, Håkan Hedman, William G. Newman & Adrian S. Woolf. (2019) Lrig2 and Hpse2, mutated in urofacial syndrome, pattern nerves in the urinary bladder. Kidney International 95:5, pages 1138-1152.
Crossref
Crossref
Jie Li, Yingjie Li, Bin Wang, Yongfu Ma & Ping Chen. (2018) LncRNA‐PCAT‐1 promotes non–small cell lung cancer progression by regulating miR‐149‐5p/LRIG2 axis. Journal of Cellular Biochemistry 120:5, pages 7725-7733.
Crossref
Crossref
Ying Chen, Qing Wang, Mi Wang & Ming Li. (2019) Overexpressed LRIG3 gene ameliorates prostate cancer through suppression of cell invasion and migration. International Journal of Biological Macromolecules 124, pages 1-9.
Crossref
Crossref
Terese Karlsson, Samuel Kvarnbrink, Camilla Holmlund, Johan Botling, Patrick Micke, Roger Henriksson, Mikael Johansson & Håkan Hedman. (2018) LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease. Lung Cancer 125, pages 174-184.
Crossref
Crossref
Michela Zamboni & Donato Civitareale. (2018) TTF-1/Nkx2.1 functional connection with mutated EGFR relies on LRIG1 and β-catenin pathways in lung cancer cells. Biochemical and Biophysical Research Communications 505:4, pages 1027-1031.
Crossref
Crossref
Pawel J. Schweiger, Ditte L. Clement, Mahalia E. Page, Troels Schepeler, Xiangang Zou, Gabor Sirokmány, Fiona M. Watt & Kim B. Jensen. (2018) Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro. Scientific Reports 8:1.
Crossref
Crossref
Eunyoung Choi, Tyler L Lantz, Gregory Vlacich, Theresa M Keeley, Linda C Samuelson, Robert J Coffey, James R Goldenring & Anne E Powell. (2018) Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach. Gut 67:9, pages 1595-1605.
Crossref
Crossref
Jinting Zhou, Lin Li, Liling Wang, Xiaofang Li, Hui Xing & Li Cheng. (2018) Establishment of a SVM classifier to predict recurrence of ovarian cancer. Molecular Medicine Reports.
Crossref
Crossref
Ruichao Chai, Kenan Zhang, Kuanyu Wang, Guanzhang Li, Ruoyu Huang, Zheng Zhao, Yanwei Liu & Jing Chen. (2018) A novel gene signature based on five glioblastoma stem-like cell relevant genes predicts the survival of primary glioblastoma. Journal of Cancer Research and Clinical Oncology 144:3, pages 439-447.
Crossref
Crossref
David Lindquist, Fernando Alsina, Carl Herdenberg, Catharina Larsson, Jo H�ppener, Na Wang, Gustavo Paratcha, Mikl�s Tarj�n, Tibor Tot, Roger Henriksson & H�kan Hedman. (2018) LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer. International Journal of Oncology.
Crossref
Crossref
Feng Mao, Camilla Holmlund, Mahmood Faraz, Wanzhong Wang, Tommy Bergenheim, Samuel Kvarnbrink, Mikael Johansson, Roger Henriksson & Håkan Hedman. (2018) Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma. Oncogenesis 7:2.
Crossref
Crossref
Jie Shen, Yuanqing Ye, David W. Chang, Maosheng Huang, John V. Heymach, Jack A. Roth, Xifeng Wu & Hua Zhao. (2017) Circulating metabolite profiles to predict overall survival in advanced non-small cell lung cancer patients receiving first-line chemotherapy. Lung Cancer 114, pages 70-78.
Crossref
Crossref
Cecilia Ranhem, Gabriella Lillsunde Larsson, Håkan Hedman, David Lindquist, Mats G. Karlsson, Ann-Cathrin Hellström, Ellinor Östensson, Bengt Sorbe, Kristina Hellman & Sonia Andersson. (2017) Expression of LRIG proteins as possible prognostic factors in primary vaginal carcinoma. PLOS ONE 12:8, pages e0183816.
Crossref
Crossref
Virginie Neirinckx, Hakan Hedman & Simone P. Niclou. (2017) Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1868:1, pages 109-116.
Crossref
Crossref
Hua YangJun YaoJiangpin YinXuan Wei. (2016) Decreased LRIG1 in Human Ovarian Cancer Cell SKOV3 Upregulates MRP-1 and Contributes to the Chemoresistance of VP16. Cancer Biotherapy and Radiopharmaceuticals 31:4, pages 125-132.
Crossref
Crossref
Susan van Erp, Dianne M.A. van den Heuvel, Yuki Fujita, Ross A. Robinson, Anita J.C.G.M. Hellemons, Youri Adolfs, Eljo Y. Van Battum, Anna M. Blokhuis, Marijn Kuijpers, Jeroen A.A. Demmers, Håkan Hedman, Casper C. Hoogenraad, Christian Siebold, Toshihide Yamashita & R. Jeroen Pasterkamp. (2015) Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Developmental Cell 35:5, pages 537-552.
Crossref
Crossref
Yang Wang, Chanjuan Shi, Yuanyuan Lu, Emily J. Poulin, Jeffery L. Franklin & Robert J. Coffey. (2015) Loss of Lrig1 Leads to Expansion of Brunner Glands Followed by Duodenal Adenomas with Gastric Metaplasia. The American Journal of Pathology 185:4, pages 1123-1134.
Crossref
Crossref
Dongsheng Guo, Hongkuan Yang, Yang Guo, Qungen Xiao, Feng Mao, Yihu Tan, Xueyan Wan, Baofeng Wang & Ting Lei. (2015) LRIG3 modulates proliferation, apoptosis and invasion of glioblastoma cells as a potent tumor suppressor. Journal of the Neurological Sciences 350:1-2, pages 61-68.
Crossref
Crossref
Eigil Kjeldsen. (2015) A novel acquired inv(2)(p23.3q24.3) with concurrent submicroscopic deletions at 2p23.3, 2p22.1, 2q24.3 and 1p13.2 in a patient with chronic thrombocytopenia and anemia. Molecular Cytogenetics 8:1, pages 7.
Crossref
Crossref