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Research Article

Age-Related Changes in the Cellular, Mechanical, and Contractile Properties of Rat Tail Tendons

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Pages 70-75 | Received 20 Aug 2012, Accepted 25 Oct 2012, Published online: 03 Dec 2012

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Read on this site (3)

Alexandru Fofiu, Robert G Tripon, Tiberiu Băţagă & Traian V Chirilă. (2023) Exogenous Crosslinking of Tendons as a Strategy for Mechanical Augmentation and Repair: A Narrative Review. Orthopedic Research and Reviews 15, pages 165-173.
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Monideepa Chatterjee, Patrick M Muljadi & Nelly Andarawis-Puri. (2022) The role of the tendon ECM in mechanotransduction: disruption and repair following overuse. Connective Tissue Research 63:1, pages 28-42.
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Cheng Zhang, Rene B. Svensson, Christian Couppé, Peter Schjerling, Dorthe Skovgaard, Michael Kjaer & S. Peter Magnusson. (2020) Regional differences in turnover, composition, and mechanics of the porcine flexor tendon. Connective Tissue Research 61:5, pages 475-484.
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Articles from other publishers (28)

Kazuki Asai, Junsuke Nakase, Toru Kuzumaki, Tatsuya Ishikawa, Noriyuki Ozaki & Hiroyuki Tsuchiya. (2023) Differences in the microstructural and mechanical qualities of semitendinosus tendon grafts between skeletally immature and mature patients in anterior cruciate ligament reconstruction. Journal of Orthopaedic Science.
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Yann Tinguely, Vivian Shi, Franka Klatte‐Schulz, Georg N. Duda, Benjamin R. Freedman & David J. Mooney. (2023) Aging and injury affect nuclear shape heterogeneity in tendon. Journal of Orthopaedic Research.
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Takuto Akazawa, Naokazu Miyamoto, Hirofumi Nishio, Eri Miyamoto-Mikami, Mayuko Kinoshita, Yohei Kobayashi, Masashi Nagao & Yuji Takazawa. (2022) Age-related changes in mechanical properties of semitendinosus tendon used for anterior cruciate ligament reconstruction. Journal of Orthopaedic Surgery and Research 17:1.
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Duc Minh Vu, Van-Tinh Nguyen, Thu Huyen Nguyen, Phuong Thi Xuan Do, Huy Hoang Dao, Do Xuan Hai, Nhi Thi Le, Xuan-Hung Nguyen & Uyen Thi Trang Than. (2022) Effects of Extracellular Vesicles Secreted by TGFβ-Stimulated Umbilical Cord Mesenchymal Stem Cells on Skin Fibroblasts by Promoting Fibroblast Migration and ECM Protein Production. Biomedicines 10:8, pages 1810.
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Benjamin R Freedman, Raphael S Knecht, Yann Tinguely, G. Ege Eskibozkurt, Cathy S. Wang & David J Mooney. (2022) Aging and matrix viscoelasticity affect multiscale tendon properties and tendon derived cell behavior. Acta Biomaterialia 143, pages 63-71.
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Kazuki Asai, Junsuke Nakase, Tatsuya Ishikawa, Rikuto Yoshimizu, Mitsuhiro Kimura, Noriyuki Ozaki & Hiroyuki Tsuchiya. (2022) Differences in cellular and microstructural properties of the semitendinosus muscle tendon between young and adult patients. Journal of Orthopaedic Science 27:2, pages 478-485.
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Marc van Vijven, Bart van Groningen, Joyce N. Kimenai, Maria C. van der Steen, Marina van Doeselaar, Rob P. A. Janssen, Keita Ito & Jasper Foolen. (2020) Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome – a diagnostic in vitro tissue remodeling platform. Journal of Experimental Orthopaedics 7:1.
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Jared R. Muench, Darryl G. Thelen & Corinne R. Henak. (2019) Interfibrillar shear behavior is altered in aging tendon fascicles. Biomechanics and Modeling in Mechanobiology 19:3, pages 841-849.
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Leila Jafari, Martin Savard, Fernand Gobeil & Eve Langelier. (2019) Characterization of moderate tendinopathy in ex vivo stress-deprived rat tail tendons. BioMedical Engineering OnLine 18:1.
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Stefania L. Wunderli, Jonas Widmer, Niklaus Amrein, Jasper Foolen, Unai Silvan, Olivier Leupin & Jess G. Snedeker. (2017) Minimal mechanical load and tissue culture conditions preserve native cell phenotype and morphology in tendon—a novel ex vivo mouse explant model. Journal of Orthopaedic Research 36:5, pages 1383-1390.
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Nicoletta Gagliano, Alessandra Menon, Federico Cabitza, Riccardo Compagnoni & Pietro Randelli. (2017) Morphological and molecular characterization of human hamstrings shows that tendon features are not influenced by donor age. Knee Surgery, Sports Traumatology, Arthroscopy 26:1, pages 343-352.
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Jessica E. Ackerman, Ibrahima Bah, Jennifer H. Jonason, Mark R. Buckley & Alayna E. Loiselle. (2017) Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing. Journal of Orthopaedic Research 35:12, pages 2716-2724.
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Daniel Huseby BordvikSturla HaslerudIngvill Fjell NaterstadRodrigo Alvaro Brandão Lopes-MartinsErnesto Cesar Pinto Leal JuniorJan Magnus BjordalJon Joensen. (2017) Penetration Time Profiles for Two Class 3B Lasers in In Situ Human Achilles at Rest and Stretched . Photomedicine and Laser Surgery 35:10, pages 546-554.
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Thiago André Carniel & Eduardo Alberto Fancello. (2017) A transversely isotropic coupled hyperelastic model for the mechanical behavior of tendons. Journal of Biomechanics 54, pages 49-57.
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Michael Lavagnino, Andrew E. Brooks, Anna N. Oslapas, Keri L. Gardner & Steven P. Arnoczky. (2017) Crimp length decreases in lax tendons due to cytoskeletal tension, but is restored with tensional homeostasis. Journal of Orthopaedic Research 35:3, pages 573-579.
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Christian Couppé, René B. Svensson, Katja M. Heinemeier, Emilie Wøjdemann Thomsen, Monika Lucia Bayer, Lise Christensen, Michael Kjær, S. Peter Magnusson & Peter Schjerling. (2016) Quantification of cell density in rat Achilles tendon: development and application of a new method. Histochemistry and Cell Biology 147:1, pages 97-102.
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Rene B. SvenssonKatja Maria Heinemeier, Christian Couppé, Michael Kjaer & S. Peter Magnusson. (2016) Effect of aging and exercise on the tendon. Journal of Applied Physiology 121:6, pages 1353-1362.
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Thijs Maria Anne Ackermans, Gaspar Epro, Christopher McCrum, Kai Daniel Oberländer, Frank Suhr, Maarten Robert Drost, Kenneth Meijer & Kiros Karamanidis. (2016) Aging and the effects of a half marathon on Achilles tendon force–elongation relationship. European Journal of Applied Physiology 116:11-12, pages 2281-2292.
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Stuart R. Young, Bruce Gardiner, Arash Mehdizadeh, Jonas Rubenson, Brian Umberger & David W. Smith. (2016) Adaptive Remodeling of Achilles Tendon: A Multi-scale Computational Model. PLOS Computational Biology 12:9, pages e1005106.
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C. T. Thorpe, B. T. McDermott, A. E. Goodship, P. D. Clegg & H. L. Birch. (2016) Ageing does not result in a decline in cell synthetic activity in an injury prone tendon. Scandinavian Journal of Medicine & Science in Sports 26:6, pages 684-693.
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Diego Pulzatto Cury, Fernando José Dias, Maria Angélica Miglino & Ii-sei Watanabe. (2016) Structural and Ultrastructural Characteristics of Bone-Tendon Junction of the Calcaneal Tendon of Adult and Elderly Wistar Rats. PLOS ONE 11:4, pages e0153568.
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Rene B. Svensson, Christian Couppé & S. Peter Magnusson. 2015. Mechanical Properties of Aging Soft Tissues. Mechanical Properties of Aging Soft Tissues 135 165 .
Kirsten Legerlotz, Jonas Dorn, Jens Richter, Martin Rausch & Olivier Leupin. (2014) Age-dependent regulation of tendon crimp structure, cell length and gap width with strain. Acta Biomaterialia 10:10, pages 4447-4455.
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Michael Lavagnino, Asheesh Bedi, Christopher P. Walsh, Elizabeth R. Sibilsky Enselman, Shahin Sheibani-Rad & Steven P. Arnoczky. (2014) Tendon Contraction After Cyclic Elongation Is an Age-Dependent Phenomenon. The American Journal of Sports Medicine 42:6, pages 1471-1477.
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B. Zhou, Y. Zhou & Kanglai Tang. (2014) An overview of structure, mechanical properties, and treatment for age-related tendinopathy. The journal of nutrition, health & aging 18:4, pages 441-448.
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Jaspreet K Kular, Shouvik Basu & Ram I Sharma. (2014) The extracellular matrix: Structure, composition, age-related differences, tools for analysis and applications for tissue engineering. Journal of Tissue Engineering 5, pages 204173141455711.
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Rie Harboe Nielsen, Lars Holm, Nikolaj Mølkjær Malmgaard-Clausen, Søren Reitelseder, Katja Maria Heinemeier & Michael Kjaer. (2014) Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men. Journal of Applied Physiology 116:1, pages 42-46.
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Natacha A. Agabalyan, Darrell J. R. Evans & Rachael L. Stanley. (2013) Investigating tendon mineralisation in the avian hindlimb: a model for tendon ageing, injury and disease. Journal of Anatomy 223:3, pages 262-277.
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