Hypertrophy of the ligament flavum in degenerative lumbar stenosis associated with the increased expression of fractalkine (CX3CL1)/CX3CR1 chemokine

In-Soo OhDepartment of Orthopaedic Surgery, Incheon St. Mary's Hospital College of Medicine, The Catholic University of KoreaSeoul, Korea

Dong-Whan SuhDepartment of Orthopaedic Surgery, Incheon St. Mary's Hospital College of Medicine, The Catholic University of KoreaSeoul, Korea

Kee-Yong HaDepartment of Orthopaedic Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea SeoulKoreaCorrespondence[email protected]

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Thomas Bitterli, David Schmid, Ladina Ettinger, Olga Krupkova, Frances C. Bach, Marianna A. Tryfonidou, Björn P. Meij, Antonio Pozzi, Frank Steffen, Karin Wuertz‐Kozak & Lucas A. Smolders. (2023) Targeted screening of inflammatory mediators in spontaneous degenerative disc disease in dogs reveals an upregulation of the tumor necrosis superfamily. JOR SPINE.
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Xiao-Wen Gao, Han-Lin Hu, Ming-Hua Xie, Cai-Xia Tang, Jun Ou & Zheng-Hao Lu. (2023) CX3CL1/CX3CR1 axis alleviates inflammation and apoptosis in human nucleus pulpous cells via M2 macrophage polarization. Experimental and Therapeutic Medicine 26:1.
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Ghanshyam Kakadiya, Kalpesh Saindane, Yogesh Soni, Kushal Gohil, Akash Shakya & Mohhamad Umair Attar. (2022) Diabetes Mellitus and the Development of Lumbar Canal Stenosis: Is There Any Relevance?. Asian Spine Journal 16:3, pages 326-333.
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Chao Sun, Han Zhang, Xiang Wang & Xinhui Liu. (2020) Ligamentum flavum fibrosis and hypertrophy: Molecular pathways, cellular mechanisms, and future directions. The FASEB Journal 34:8, pages 9854-9868.
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Eliezer Sidon, Shai S. Shemesh, Lisa Mor‐Yossef Moldovan, Yarden Wiesenfeld, Nissim Ohana & Dafna Benayahu. (2019) Molecular profile of ultrastructure changes of the ligamentum flavum related to lumbar spinal canal stenosis. Journal of Cellular Biochemistry 120:7, pages 11716-11725.
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Shai Shemesh, Eliezer Sidon, Efrat Kaisler, Dimitry Sheinis, Steven Velkes, Nissim Ohana & Dafna Benayahu. (2017) Diabetes mellitus is associated with increased elastin fiber loss in ligamentum flavum of patients with lumbar spinal canal stenosis: results of a pilot histological study. European Spine Journal 27:7, pages 1614-1622.
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Yutaka Yabe, Yoshihiro Hagiwara, Akira Ando, Masahiro Tsuchiya, Takashi Minowa, Taro Takemura, Masahito Honda, Kouki Hatori, Kazuaki Sonofuchi, Kenji Kanazawa, Masashi Koide, Takuya Sekiguchi & Eiji Itoi. (2015) Chondrogenic and Fibrotic Process in the Ligamentum Flavum of Patients With Lumbar Spinal Canal Stenosis. Spine 40:7, pages 429-435.
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Hypertrophy of the ligament flavum in degenerative lumbar stenosis associated with the increased expression of fractalkine (CX3CL1)/CX3CR1 chemokine

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Hypertrophy of the ligament flavum in degenerative lumbar stenosis associated with the increased expression of fractalkine (CX3CL1)/CX3CR1 chemokine

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