Citations (17)
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H. E. Gruber, E. Marrero, M. Cox & Edward Hanley$suffix/text()$suffix/text(). (2019) Interleukin-23 is constitutively expressed in the human annulus in vivo and in vitro, and is up-regulated in vitro by TNF-α. Biotechnic & Histochemistry 94:7, pages 540-545.
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HE Gruber & EN Hanley Jr. (2018) Expression of serglycin in human disc is increased in degenerated discs and up-regulated in vitro by exposure to IL-1ß or TNF-α. Biotechnic & Histochemistry 93:2, pages 109-117.
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HE Gruber, E Marrero, JA Ingram, GL Hoelscher & EN Hanley$suffix/text()$suffix/text(). (2017) Constitutive expression of IL-22 in the human intervertebral disc and its reduction by exposure to pro-inflammatory cytokines in vitro. Biotechnic & Histochemistry 92:3, pages 222-229.
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HE Gruber, E Marrero, JA Ingram, GL Hoelscher & EN Hanley$suffix/text()$suffix/text(). (2017) The chemokine, CXCL16, and its receptor, CXCR6, are constitutively expressed in human annulus fibrosus and expression of CXCL16 is up-regulated by exposure to IL-1ß in vitro. Biotechnic & Histochemistry 92:1, pages 7-14.
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Articles from other publishers (13)
Hui Lin, Shuo Tian, Yizhong Peng, Ling Wu, Yan Xiao, Xiangcheng Qing & Zengwu Shao. (2022) IGF Signaling in Intervertebral Disc Health and Disease. Frontiers in Cell and Developmental Biology 9.
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Antti Pemmari, Lauri Tuure, Mari Hämäläinen, Tiina Leppänen, Teemu Moilanen & Eeva Moilanen. (2021) Effects of ibuprofen on gene expression in chondrocytes from patients with osteoarthritis as determined by RNA-Seq. RMD Open 7:3, pages e001657.
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Rikke Hjortebjerg, Karen L. Thomsen, Jørgen Agnholt & Jan Frystyk. (2019) The IGF system in patients with inflammatory bowel disease treated with prednisolone or infliximab: potential role of the stanniocalcin-2 / PAPP-A / IGFBP-4 axis. BMC Gastroenterology 19:1.
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Helen E. Gruber, Jane A. Ingram, Gretchen L. Hoelscher, Emilio Marrero & Edward N. HanleyJrJr. (2017) Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α. BMC Musculoskeletal Disorders 18:1.
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Helen E. Gruber, Brittany Jones, Emilio Marrero & Edward N. Hanley. (2017) Proinflammatory Cytokines IL-1β and TNF-α Influence Human Annulus Cell Signaling Cues for Neurite Growth. Spine 42:20, pages 1529-1537.
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Sun FuWang LeiDai LanlanYuan Qi-lingLiu LiangZhou HanlinZhang JianguoZhang Yin-gang. (2017)
Whole Exome Sequencing Identified a Novel
IGFBP6
Variant in a Disc Degeneration Pedigree
. Genetic Testing and Molecular Biomarkers 21:10, pages 580-585.
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Cheryl A. Conover & Claus Oxvig. (2017) PAPP-A: a promising therapeutic target for healthy longevity. Aging Cell 16:2, pages 205-209.
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Helen E. Gruber, Gretchen L. Hoelscher, Jane A. Ingram, Synthia Bethea & Edward N. HanleyJrJr. (2015) Autophagy in the Degenerating Human Intervertebral Disc. Spine 40:11, pages 773-782.
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Helen E. Gruber, Gretchen L. Hoelscher, Synthia Bethea, Jane Ingram, Michael Cox & Edward N. HanleyJr.Jr.. (2015) High-mobility group box-1 gene, a potent proinflammatory mediators, is upregulated in more degenerated human discs in vivo and its receptor upregulated by TNF-α exposure in vitro. Experimental and Molecular Pathology 98:3, pages 427-430.
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Helen E. Gruber, Gretchen L. Hoelscher, Jane A. Ingram, Synthia Bethea, Michael Cox & Edward N. HanleyJr.Jr.. (2015) Proinflammatory cytokines modulate the chemokine CCL2 (MCP-1) in human annulus cells in vitro: CCL2 expression and production. Experimental and Molecular Pathology 98:1, pages 102-105.
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Helen E. Gruber, Gretchen L. Hoelscher, Synthia F. Bethea, Evan A. Menscher, Jane A. Ingram, Megan A. Templin & Edward N. HanleyJr.Jr.. (2014) Cortistatin is endogenous to the human intervertebral disc and exerts in vitro mitogenic effects on annulus cells and a downregulatory effect on TNF-α expression. The Spine Journal 14:12, pages 2995-3001.
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Dae-Ho Jang, Youngbo Choi, Yong-Soo Choi, Sun-Mi Kim, Hojung Kwak, Se-Hyun Shin & Surin Hong. (2014) Sensitive and selective analysis of a wide concentration range of IGFBP7 using a surface plasmon resonance biosensor. Colloids and Surfaces B: Biointerfaces 123, pages 887-891.
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Helen E. Gruber, Gretchen L. Hoelscher, Jane A. Ingram, Synthia Bethea & Edward N. HanleyJr.Jr.. (2014) Growth and differentiation factor-5 (GDF-5) in the human intervertebral annulus cells and its modulation by IL-1ß and TNF-α in vitro. Experimental and Molecular Pathology 96:2, pages 225-229.
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