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Connective Tissue Research Volume 29, 1993 - Issue 2
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Original Article

Is the Antioxidant, Anti-Inflammatory Utative New Vitamin, PQQ, Involved with Nitric Oxide in Bone Metabolism?

Paul M. Gallop Laboratory of Human Biochemistry, Children's Hospital, 300 Longwood Avenue, Boston, MA, 02155, USA; Department of Oral Biology, Harvard School of Dental Medicine, Boston, MA, USA; Department of Biological Chemistry, Harvard Medical School, Boston, MA, USA
,
Mercedes A. Paz Laboratory of Human Biochemistry, Children's Hospital, 300 Longwood Avenue, Boston, MA, 02155, USA; Department of Oral Biology, Harvard School of Dental Medicine, Boston, MA, USA
,
Rudolf Fluckiger Laboratory of Human Biochemistry, Children's Hospital, 300 Longwood Avenue, Boston, MA, 02155, USA; Department of Oral Biology, Harvard School of Dental Medicine, Boston, MA, USA
&
Edward Henson Laboratory of Human Biochemistry, Children's Hospital, 300 Longwood Avenue, Boston, MA, 02155, USA
Pages 153-161 | Received 19 Nov 1991, Accepted 09 Jan 1992, Published online: 07 Jul 2009

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Takeshi ISHII, Mitsugu AKAGAWA, Yuji NAITO, Osamu HANDA, Tomohisa TAKAGI, Taiki MORI, Shigenori KUMAZAWA, Toshikazu YOSHIKAWA & Tsutomu NAKAYAMA. (2010) Pro-Oxidant Action of Pyrroloquinoline Quinone: Characterization of Protein Oxidative Modifications. Bioscience, Biotechnology, and Biochemistry 74:3, pages 663-666.
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Articles from other publishers (14)

Hirohide Toyama. 2016. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants 367 388 .
Zhongbing Liu, Chi Sun, Ran Tao, Xinbao Xu, Libin Xu, Hongbing Cheng, Youhua Wang & Dongmei Zhang. (2015) Pyrroloquinoline Quinone Decelerates Rheumatoid Arthritis Progression by Inhibiting Inflammatory Responses and Joint Destruction via Modulating NF-κB and MAPK Pathways. Inflammation 39:1, pages 248-256.
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Chongfei Yang, Lifeng Yu, Lingbo Kong, Rui Ma, Juliang Zhang, Qingsheng Zhu, Jinyu Zhu & Dingjun Hao. (2014) Pyrroloquinoline Quinone (PQQ) Inhibits Lipopolysaccharide Induced Inflammation in Part via Downregulated NF-κB and p38/JNK Activation in Microglial and Attenuates Microglia Activation in Lipopolysaccharide Treatment Mice. PLoS ONE 9:10, pages e109502.
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Lingbo Kong, Chongfei Yang, Lifeng Yu, Wanli Smith, Shu Zhu, Jinyu Zhu & Qingsheng Zhu. (2013) Pyrroloquinoline Quinine Inhibits RANKL-Mediated Expression of NFATc1 in Part via Suppression of c-Fos in Mouse Bone Marrow Cells and Inhibits Wear Particle-Induced Osteolysis in Mice. PLoS ONE 8:4, pages e61013.
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Lili ZhangJie LiuChun ChengYing YuanBiyun YuAiguo ShenMeijuan Yan. (2012) The Neuroprotective Effect of Pyrroloquinoline Quinone on Traumatic Brain Injury. Journal of Neurotrauma 29:5, pages 851-864.
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Erdenezaya Odkhuu, Naoki Koide, Abedul Haque, Bilegtsaikhan Tsolmongyn, Yoshikazu Naiki, Shoji Hashimoto, Takayuki Komatsu, Tomoaki Yoshida & Takashi Yokochi. (2012) Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ). Immunology Letters 142:1-2, pages 34-40.
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Aya Ouchi, Masahiko Nakano, Shin-ichi Nagaoka & Kazuo Mukai. (2008) Kinetic Study of the Antioxidant Activity of Pyrroloquinolinequinol (PQQH 2 , a Reduced Form of Pyrroloquinolinequinone) in Micellar Solution . Journal of Agricultural and Food Chemistry 57:2, pages 450-456.
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Yonghua Zhang, Paul J. Feustel & Harold K. Kimelberg. (2006) Neuroprotection by pyrroloquinoline quinone (PQQ) in reversible middle cerebral artery occlusion in the adult rat. Brain Research 1094:1, pages 200-206.
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Bo-qing Zhu, Hui-zhong Zhou, John R Teerlink & Joel S Karliner. (2004) Pyrroloquinoline Quinone (PQQ) Decreases Myocardial Infarct Size and Improves Cardiac Function in Rat Models of Ischemia and Ischemia/Reperfusion. Cardiovascular Drugs and Therapy 18:6, pages 421-431.
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Victor L Davidson. 2001. Novel Cofactors. Novel Cofactors 95 140 .
Amy Bishop, Paul M. Gallop & Manfred L. Karnovsky. (2009) Pyrroloquinoline Quinone: A Novel Vitamin?. Nutrition Reviews 56:10, pages 287-293.
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Joelle M Scanlon, Elias Aizenman & Ian J Reynolds. (1997) Effects of pyrroloquinoline quinone on glutamate-induced production of reactive oxygen species in neurons. European Journal of Pharmacology 326:1, pages 67-74.
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M.A Glinn, C.P Lee & L Ernster. (1997) Pro- and anti-oxidant activities of the mitochondrial respiratory chain: factors influencing NAD(P)H-induced lipid peroxidation. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1318:1-2, pages 246-254.
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H. Xu, B. A. Watkins & M. F. Seifert. (1995) Vitamin E stimulates trabecular bone formation and alters epiphyseal cartilage morphometry. Calcified Tissue International 57:4, pages 293-300.
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