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Case Report

Treatment of Schnitzler's syndrome with anakinra: report of three cases and review of the literature

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Pages 74-79 | Accepted 13 May 2010, Published online: 11 Oct 2010

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Kyle Tegtmeyer, Giancarlo Atassi, Jeffrey Zhao, Nolan J. Maloney & Peter A. Lio. (2022) Off-Label studies on anakinra in dermatology: a review. Journal of Dermatological Treatment 33:1, pages 73-86.
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Astrid Sönnichsen, Ieva Saulite, Johanna Mangana, Katrin Kerl, Tarun Mehra, Ignatova Desislava, Yun-Tsan Chang, Ulf Petrausch, Peter Schmid-Grendelmeier, Wolfram Hoetzenecker, Antonio Cozzio & Emmanuella Guenova. (2016) Interleukin-1 receptor antagonist (anakinra) for Schnitzler syndrome. Journal of Dermatological Treatment 27:5, pages 436-438.
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Dan Lipsker & Cédric Lenormand. (2014) Management of Schnitzler’s syndrome. Expert Opinion on Orphan Drugs 2:9, pages 947-955.
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Articles from other publishers (21)

Elle Levit, Janice LeonMatthew R. Lincoln. (2023) Pearls & Oy-sters: Homozygous Complement Factor I Deficiency Presenting as Fulminant Relapsing Complement-Mediated CNS Vasculitis. Neurology 101:2.
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Dennis D. Arnold, Ayla Yalamanoglu & Onur Boyman. (2022) Systematic Review of Safety and Efficacy of IL-1-Targeted Biologics in Treating Immune-Mediated Disorders. Frontiers in Immunology 13.
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E. L. Nasonov & M. Yu. Samsonov. (2022) The role of interleukin 1 in the development of human diseases: focus on Anakinra (IL-1 receptor antagonist). Rheumatology Science and Practice 60:3, pages 280-298.
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Fawad Aslam, Julia E. Wiedmeier & David J. DiCaudo. (2021) A Man With Recurrent Fever, Episodic Rash, and Pain. Arthritis Care & Research 73:8, pages 1106-1113.
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Silvia Stefania, Ripalta Colia, Rotondo Cinzia, Addolorata Corrado & Francesco Paolo Cantatore. (2021) Off-label use of anti-IL-1 drugs in rheumatic diseases. International Journal of Immunopathology and Pharmacology 35, pages 205873842110065.
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S O Salugina, V R Gorodetsky, E S Fedorov, N E Lopatina & M D Evsikova. (2017) Schnitzler syndrome: A review of literature, the authors’ observation, and experience with the interleukin-1 inhibitor canakinumab. Terapevticheskii arkhiv 89:11, pages 111-115.
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Linda Rossi-Semerano, Bruno Fautrel, Daniel Wendling, Eric Hachulla, Caroline Galeotti, Luca Semerano, Isabelle Touitou & Isabelle Koné-Paut. (2015) Tolerance and efficacy of off-label anti-interleukin-1 treatments in France: a nationwide survey. Orphanet Journal of Rare Diseases 10:1, pages 19.
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Achille Aouba, Claire Pressiat, Maria Pricopi, Sophie Georgin-Lavialle, François Boue, Maria-Angela Lievre-Castilla, Anne Marfaing-Koka, Sophie Prevot & Audrey Decottignies. (2015) Complete Remission of Schnitzler Syndrome and Waldenström Macroglobulinemia under Rituximab-Cyclophosphamide-Dexamethasone. Dermatology 230:1, pages 18-22.
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Y. Jamilloux, P. Sève & T. Henry. (2014) Les inflammasomes et les maladies humaines. La Revue de Médecine Interne 35:11, pages 730-741.
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Antoine Néel, Benoit Henry, Sebastien Barbarot, Agathe Masseau, François Perrin, Claire Bernier, Xavier Kyndt, Xavier Puechal, Pierre-Jean Weiller, Olivier Decaux, Jacques Ninet, Arnaud Hot, Achille Aouba, Leonardo Astudillo, Jean-Marie Berthelot, Fabrice Bonnet, Jean-Marie Brisseau, Bérangère Cador, Fabienne Closs-Prophette, Thomas Dejoie, Jean-Dominique de Korwin, Robin Dhote, Renato Fior, Bernard Grosbois, Eric Hachulla, Pierre-Yves Hatron, Henry Jardel, David Launay, Adrien Lorleac'h, Pierre Pottier, Guillaume Moulis, Jacques Serratrice, Amar Smail & Mohamed Hamidou. (2014) Long-term effectiveness and safety of interleukin-1 receptor antagonist (anakinra) in Schnitzler's syndrome: A french multicenter study. Autoimmunity Reviews 13:10, pages 1035-1041.
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Ingo Hartig, Johann Oltmann Schroeder & Ulrich Mrowietz. (2014) Neutrophilic Urticarial Dermatosis (NUD) in Probable Adult-Onset Still Disease Responding to Anakinra. JCR Journal of Clinical Rheumatology 20:2, pages 96-98.
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François Perrin, Antoine Néel, Julie Graveleau, Anne-Lise Ruellan, Agathe Masseau & Mohamed Hamidou. (2014) Two cases of anakinra-induced neutropenia during auto-inflammatory diseases: Drug reintroduction can be successful. La Presse Médicale 43:3, pages 319-321.
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Torsten Zuberbier & Marcus Maurer. (2014) Urticarial Vasculitis and Schnitzler Syndrome. Immunology and Allergy Clinics of North America 34:1, pages 141-147.
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Charles Anthony Dinarello. (2014) An Expanding Role for Interleukin-1 Blockade from Gout to Cancer. Molecular Medicine 20:S1, pages S43-S58.
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Heleen D Koning. (2014) Schnitzler's syndrome: lessons from 281 cases. Clinical and Translational Allergy 4:1, pages 41.
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Giuseppe TridenteGiuseppe Tridente. 2014. Adverse Events with Biomedicines. Adverse Events with Biomedicines 539 550 .
Charles A. Dinarello & Jos W.M. van der Meer. (2013) Treating inflammation by blocking interleukin-1 in humans. Seminars in Immunology 25:6, pages 469-484.
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Heleen D de Koning, Joost Schalkwijk, Johanna van der Ven-Jongekrijg, Monique Stoffels, Jos W M van der Meer & Anna Simon. (2013) Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler's syndrome. Annals of the Rheumatic Diseases 72:10, pages 1634-1638.
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B. Henry, A. Néel, S. Barbarot, A. Masseau & M. Hamidou. (2013) Le syndrome de Schnitzler. La Revue de Médecine Interne 34:4, pages 224-229.
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Sinisa Savic, Laura J. Dickie, Miriam Wittmann & Michael F. McDermott. (2012) Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives. Best Practice & Research Clinical Rheumatology 26:4, pages 505-533.
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K. Krause, K. Weller, R. Stefaniak, H. Wittkowski, S. Altrichter, F. Siebenhaar, T. Zuberbier & M. Maurer. (2012) Efficacy and safety of the interleukin‐1 antagonist rilonacept in S chnitzler syndrome: an open‐label study . Allergy 67:7, pages 943-950.
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