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Research Article

Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin–Beck disease)

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Pages 71-79 | Accepted 25 May 2012, Published online: 17 Nov 2012

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M Garcia-Montojo, J Varade, E Villafuertes, B de La Hera, J Hoyas-Fernandez, MI Domínguez-Mozo, L Rodriguez-Rodriguez, P Tornero-Esteban, A Arias-Leal, L León, JR Lamas, R Alvarez-Lafuente, E Urcelay & B Fernandez-Gutierrez. (2013) Expression of human endogenous retrovirus HERV-K18 is associated with clinical severity in osteoarthritis patients. Scandinavian Journal of Rheumatology 42:6, pages 498-504.
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Ying He, Lihong Fan, Nicole Aaron, Yiping Feng, Qian Fang, Ying Zhang, Dan Zhang, Hui Wang, Tianyou Ma, Jian Sun & Jinghong Chen. (2022) Reduction of Smad2 caused by oxidative stress leads to necrotic death of hypertrophic chondrocytes associated with an endemic osteoarthritis. Rheumatology 61:1, pages 440-451.
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Bin Xiao, Guozhu Wang, Hongliang Huo & Weiwei Li. (2021) Identification of HIF‑1α/VEGFA signaling pathway and transcription factors in Kashin‑Beck disease by integrated bioinformatics analysis. Experimental and Therapeutic Medicine 22:4.
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Ying He, Ying Zhang, Dan Zhang, Meng Zhang, Mengying Wang, Zhuocheng Jiang, Miguel Otero & Jinghong Chen. (2018) 3-morpholinosydnonimine (SIN-1)-induced oxidative stress leads to necrosis in hypertrophic chondrocytes in vitro. Biomedicine & Pharmacotherapy 106, pages 1696-1704.
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Mikko Lammi & Chengjuan Qu. (2018) Selenium-Related Transcriptional Regulation of Gene Expression. International Journal of Molecular Sciences 19:9, pages 2665.
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Ying He, Wen Yao, Meng Zhang, Ying Zhang, Dan Zhang, Zhuocheng Jiang, Tianyou Ma, Jian Sun, Mingming Shao & Jinghong Chen. (2018) Changes in osteogenic gene expression in hypertrophic chondrocytes induced by SIN‑1. Experimental and Therapeutic Medicine.
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Changxing Wang, Weidong Wang, Xiaping Jin, Jianguo Shen, Weifeng Hu & Tao Jiang. (2016) Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling. Molecular Medicine Reports 14:2, pages 1365-1370.
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Jing Han, Weizhuo Wang, Chengjuan Qu, Ruiyu Liu, Wenrong Li, Zongqiang Gao & Xiong Guo. (2015) Role of inflammation in the process of clinical Kashin-Beck disease: latest findings and interpretations. Inflammation Research 64:11, pages 853-860.
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X. Guo, W.-J. Ma, F. Zhang, F.-L. Ren, C.-J. Qu & M.J. Lammi. (2014) Recent advances in the research of an endemic osteochondropathy in China: Kashin-Beck disease. Osteoarthritis and Cartilage 22:11, pages 1774-1783.
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Yini Ma, Rongheng Li, Yudi Zhang, Lingyun Zhou & Yehong Dai. (2014) Knockdown of peroxiredoxin 5 inhibits the growth of osteoarthritic chondrocytes via upregulating Wnt/β-catenin signaling. Free Radical Biology and Medicine 76, pages 251-260.
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Shi-Xun Wu, Wei-Zhuo Wang, Feng Zhang, Cui-Yan Wu, Bannel.S. Dennis, Cheng-Juan Qu, Yi-Dong Bai & Xiong Guo. (2014) Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin–Beck osteoarthritis. Gene 535:2, pages 124-130.
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