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Drug Metabolism Reviews Volume 5, 1976 - Issue 2
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Research Article

Methods for Obtaining Drug Time Course Data from Individual Small laboratory Animals: Serial Microblood Sampling and Assay

Bruce H. Migdalof Department of Biochemical Research, McNeil Laboratories, Inc., Fort Washington, Pennsylvania, 19034
Pages 295-310 | Published online: 22 Sep 2008

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F. C. P. Law, Y. Y. Song & S. Chakrabarti. (1983) Disposition and metabolism of diphenyl ether in rats. Xenobiotica 13:10, pages 627-633.
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Articles from other publishers (33)

David J. Wagner, Aixiang Xue, Guangnong Zhang, Eric Gosselin, Nakpangi Johnson & Eric T. Gangl. (2021) Generation of High-Quality Pharmacokinetic Data From Parallel Tail Vein Dosing And Bleeding in Non-cannulated Rats. Journal of Pharmaceutical Sciences 110:10, pages 3491-3499.
Crossref
Annie Y. Park, Paul M. Plotsky, Truyen D. Pham, Karel Pacak, Brandi M. Wynne, Susan M. Wall & Yoskaly Lazo-Fernandez. (2018) Blood collection in unstressed, conscious, and freely moving mice through implantation of catheters in the jugular vein: a new simplified protocol. Physiological Reports 6:21, pages e13904.
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Ioannis Christakis, Panagiotis Georgiou, James Minnion, Vasilis Constantinides, Joyceline Cuenco, Rebecca Scott, Tricia Tan, Fausto Palazzo, Kevin Murphy & Stephen Bloom. (2015) Learning curve of vessel cannulation in rats using cumulative sum analysis. Journal of Surgical Research 193:1, pages 69-76.
Crossref
Barry Levine. 2014. Handbook of Toxicology, Third Edition. Handbook of Toxicology, Third Edition.
Arthur L. M. SwislockiZarlasht Fakiri. (2008) Smokeless Nicotine Exposure Has No Lasting Effect on Fasting or Postglucose Circulation Leptin in Young Rats. Metabolic Syndrome and Related Disorders 6:4, pages 257-262.
Crossref
A.L.M. Swislocki. (2003) Smokeless nicotine administration does not result in hypertension or a deterioration in glucose tolerance or insulin sensitivity in juvenile rats. Metabolism 52:1, pages 67-72.
Crossref
Barry Levine. 2001. Handbook of Toxicology, Second Edition. Handbook of Toxicology, Second Edition.
A.L.M. Swislocki, A. Tsuzuki, M. Tait, D. Khuu & K. Fann. (1997) Smokeless nicotine administration is associated with hypertension but not with a deterioration in glucose tolerance in rats. Metabolism 46:9, pages 1008-1012.
Crossref
Ene I. Ette, Andrew W. Kelman, Catherine A. Howie & Brian Whiting. (1995) Analysis of animal pharmacokinetic data: Performance of the one point per animal design. Journal of Pharmacokinetics and Biopharmaceutics 23:6, pages 551-566.
Crossref
Arthur Swislocki & Akiko Tsuzuki. (1993) Insulin Resistance and Hypertension: Glucose Intolerance, Hyperinsulinemia, and Elevated Free Fatty Acids in the Lean Spontaneously Hypertensive Rat. The American Journal of the Medical Sciences 306:5, pages 282-286.
Crossref
Patricia Frank, Grant L. Schoenhard & Earl Burton. (1991) A method for rapid and frequent blood collection from the rat tail vein. Journal of Pharmacological Methods 26:3, pages 233-238.
Crossref
T D Gootz. (1990) Discovery and development of new antimicrobial agents.. Clinical Microbiology Reviews 3:1, pages 13-31.
Crossref
Yun-Cheung Chui, Grace Poon & Francis Law. (2017) Toxicokinetics and Bioavailability of Paraquat in Rats following Different Routes of Administration. Toxicology and Industrial Health 4:2, pages 203-219.
Crossref
Russell A. Van Dyke, Kimberly L. Kooistra, C.Jill Moses & Garth Powis. (1987) Effect of inhalation anesthetics on antipyrine pharmacokinetics of mice. Biochemical Pharmacology 36:7, pages 1023-1027.
Crossref
Johnny A. Mitchell & Marvin C. Wilson. (1987) The behavioral and toxicological effects of testosterone pellet implantation. Physiology & Behavior 41:5, pages 427-432.
Crossref
M.D. Green, B.G. Talbot & C.R. Clark. (1986) Pharmacokinetics of pralidoxime chloride in the rat. Life Sciences 39:23, pages 2263-2269.
Crossref
David J. Moore & Garth Powis. (1986) Disposition and metabolism of the antitumor glycoside phyllanthoside in mouse and beagle dog. Cancer Chemotherapy and Pharmacology 16:3, pages 218-222.
Crossref
Cecil F. Brownie & Arthur L. Aronson. (1984) Comparative effects of Ca-ethylenediaminetetraacetic acid (EDTA), ZnEDTA, and ZnCaEDTA in mobilizing lead. Toxicology and Applied Pharmacology 75:2, pages 167-172.
Crossref
S. Chakrabarti & F. C. P. Law. (1983) The dispositional kinetics of phencyclidine and itsN-ethylamine analogue in rats. European Journal of Drug Metabolism and Pharmacokinetics 8:4, pages 383-388.
Crossref
Shamsul K. Bakar & Sarfaraz Niazi. (1983) Simple Reliable Method for Chronic Cannulation of the Jugular Vein for Pharmacokinetic Studies in Rats. Journal of Pharmaceutical Sciences 72:9, pages 1027-1029.
Crossref
David M. Cocchetto & Thorir D. Bjornsson. (1983) Methods for Vascular Access and Collection of Body Fluids from the Laboratory Rat. Journal of Pharmaceutical Sciences 72:5, pages 465-492.
Crossref
James H. HarrisonJr.Jr. & David J. Jollow. (1983) Rapid and sensitive method for the microassay of nitrosobenzene plus phenylhydroxylamine in blood. Journal of Chromatography B: Biomedical Sciences and Applications 277, pages 173-182.
Crossref
Wenche M. Johannessen, Ingvald M. Tyssebotn & Jarle Aarbakke. (1982) Antipyrine and Acetaminophen Kinetics in the Rat: Comparison of Data Based on Blood Samples from the Cut Tail and a Cannulated Femoral Artery. Journal of Pharmaceutical Sciences 71:12, pages 1352-1356.
Crossref
Anne Reid, Francis W. Smith & James M. S. Hutchison. (1982) Nuclear magnetic resonance imaging and its safety implications: follow-up of 181 patients. The British Journal of Radiology 55:658, pages 784-786.
Crossref
M. V. Williams & J. Denekamp. (1982) Blood samples from mice: the influence of sampling site. The British Journal of Radiology 55:658, pages 782-784.
Crossref
Robert V. Smith, Allen E. Klein, Richard E. Wilcox & William H. Riffee. (1981) Apomorphine: Bioavailability and Effect on Stereotyped Cage Climbing in Mice. Journal of Pharmaceutical Sciences 70:10, pages 1144-1147.
Crossref
Johnny BazareJr.Jr., Mary Lee Leamons & John F. Young. (1981) Sampling methods for pharmacokinetic studies in the mouse. Journal of Pharmacological Methods 5:2, pages 99-120.
Crossref
P.W. MULLEN. 1981. Advances in Immunopharmacology. Advances in Immunopharmacology 3 9 .
David M. Cocchetto, William A. Wargin & James W. Crow. (1980) Pitfalls and valid approaches to pharmacokinetic analysis of mean concentration data following intravenous administration. Journal of Pharmacokinetics and Biopharmaceutics 8:6, pages 539-552.
Crossref
. (2012) Proceedings of the British Pharmacological Society. British Journal of Pharmacology 67:3.
Crossref
Thomas M. Lehman, Padma Pyati & George R. Peterson. (1979) Inhibition of drug metabolism by chronically administered naltrexone. Life Sciences 25:18, pages 1591-1600.
Crossref
J. F. M. Smits & H. A. J. Struyker-Boudier. (1979) Propranolol in conscious spontaneously hypertensive rats. Naunyn-Schmiedeberg's Archives of Pharmacology 309:1, pages 19-24.
Crossref
Bruce H. Migdalof. 1978. 196 205 .

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