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Research Article

History of Drug Metabolism: The First Half of the 20th Century

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Pages 185-253 | Published online: 22 Sep 2008

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Read on this site (8)

Alan Wayne Jones. (2015) Profiles in drug metabolism and toxicology: Richard Tecwyn Williams (1909–1979). Drug Metabolism Reviews 47:4, pages 401-405.
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Stephen C. Mitchell, Rosemary H. Waring & Robert L. Smith. (2014) Curiosities in drug metabolism. Xenobiotica 44:7, pages 666-676.
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Debra Luffer-Atlas. (2012) The early estimation of circulating drug metabolites in humans. Expert Opinion on Drug Metabolism & Toxicology 8:8, pages 985-997.
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F. Peter Guengerich. (2004) Cytochrome P450: What Have We Learned and What Are the Future Issues?. Drug Metabolism Reviews 36:2, pages 159-197.
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Dennis V. Parke. (1997) A History of Drug Metabolism in the United Kingdom. Drug Metabolism Reviews 29:3, pages 801-851.
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Jordan L. Holtzman. (1995) The Role of Covalent Binding to Microsomal Proteins in the Hepatotoxicity of Acetaminophen. Drug Metabolism Reviews 27:1-2, pages 277-297.
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Ed Nelson. (1992) Determination of Mercapturic Acid Excretions in Exposure Control to Toxicants. Critical Reviews in Toxicology 22:5-6, pages 371-389.
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Frederick J. Di Carlo, James D. Adams & Nadine Adams. (1992) Carl Paxson Sherwin, American Pioneer in Drug Metabolism. Drug Metabolism Reviews 24:4, pages 493-530.
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Articles from other publishers (22)

Alan Wayne Jones. (2023) Brief history of the alcohol biomarkers CDT, EtG, EtS, 5‐HTOL, and PEth. Drug Testing and Analysis.
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Emre M. Isin. (2023) Unusual Biotransformation Reactions of Drugs and Drug Candidates. Drug Metabolism and Disposition 51:4, pages 413-426.
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ROBERTA S. KING. 2022. Drug Metabolism Handbook. Drug Metabolism Handbook 1 12 .
F. Peter Guengerich. (2020) A history of the roles of cytochrome P450 enzymes in the toxicity of drugs. Toxicological Research 37:1, pages 1-23.
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Vivian Delcourt, Agnès Barnabé, Benoit Loup, Patrice Garcia, François André, Benjamin Chabot, Stéphane Trévisiol, Yves Moulard, Marie-Agnès Popot & Ludovic Bailly-Chouriberry. (2020) MetIDfyR: An Open-Source R Package to Decipher Small-Molecule Drug Metabolism through High-Resolution Mass Spectrometry. Analytical Chemistry 92:19, pages 13155-13162.
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J.Y. Cui & C.Y. Li. 2018. Comprehensive Toxicology. Comprehensive Toxicology 168 214 .
Gerald T. Miwa & Arthur K. Cho. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 25 .
Olujide Tokunbo Akinbo. 2013. Teaching Bioanalytical Chemistry. Teaching Bioanalytical Chemistry 23 56 .
Hana Raoof, Przemyslaw Mielczarek, Katarzyna A. Michalow, Mieczyslaw Rekas & Jerzy Silberring. (2013) Synthesis of metabolites of paracetamol and cocaine via photooxidation on TiO2 catalyzed by UV light. Journal of Photochemistry and Photobiology B: Biology 118, pages 49-57.
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Ulrich M. Zanger. 2012. Metabolism of Drugs and Other Xenobiotics. Metabolism of Drugs and Other Xenobiotics 285 300 .
Alexander V. LyubimovShelby Anderson, Debra Luffer‐Atlas & Mary Pat Knadler. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 27 .
A. Wayne Jones. 2012. Handbook of Drug Interactions. Handbook of Drug Interactions 499 586 .
Roberta S. King. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 12 .
R.I. Sanchez & F.C. Kauffman. 2010. Comprehensive Toxicology. Comprehensive Toxicology 109 128 .
J. S. Forbey & W. J. Foley. (2009) PharmEcology: A pharmacological approach to understanding plant-herbivore interactions: an introduction to the symposium. Integrative and Comparative Biology 49:3, pages 267-273.
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Roberta S. King. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook 1 12 .
Kenneth Bachmann. 2009. Pharmacology. Pharmacology 131 173 .
Patrick J. Murphy. (2008) The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 1, 1909–1958. Drug Metabolism and Disposition 36:1, pages 1-5.
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Alan Wayne Jones & Anders Helander. 2007. Forensic Issues in Alcohol Testing. Forensic Issues in Alcohol Testing 91 118 .
Rubin Gulaboski, M. Natalia D.S. Cordeiro, Nuno Milhazes, Jorge Garrido, Fernanda Borges, Miguel Jorge, Carlos M. Pereira, Ivan Bogeski, Aluska Helguera Morales, Blaze Naumoski & A. Fernando Silva. (2007) Evaluation of the lipophilic properties of opioids, amphetamine-like drugs, and metabolites through electrochemical studies at the interface between two immiscible solutions. Analytical Biochemistry 361:2, pages 236-243.
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Alan Wayne Jones. 2006. Drug Abuse Handbook, Second Edition. Drug Abuse Handbook, Second Edition 313 427 .
A. W. Jones. 1991. Forensic Science Progress 5. Forensic Science Progress 5 31 89 .

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