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Drug Metabolism Reviews Volume 27, 1995 - Issue 1-2
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Research Article

In Vivo Characterization and Modulation of the Glutathione/Glutathione S-Transferase System in Cancer Patients

Titia M. T. Mulders Leiden/Amsterdam Center for Drug Research, Divisions of Toxicology and Pharmacology, Leiden University, Leiden, The Netherlands
,
Jan Keizer University Hospital Leiden, Division of Clinical Oncology, Leiden, The Netherlands
,
Douwe D. Breimer Leiden/Amsterdam Center for Drug Research, Divisions of Toxicology and Pharmacology, Leiden University, Leiden, The Netherlands
&
Gerard J. Mulder Leiden/Amsterdam Center for Drug Research, Divisions of Toxicology and Pharmacology, Leiden University, Leiden, The Netherlands
Pages 191-229 | Published online: 22 Sep 2008

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Dennis V. Parke. (1997) A History of Drug Metabolism in the United Kingdom. Drug Metabolism Reviews 29:3, pages 801-851.
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Jessica R. Vargas, Erika Geihe Stanzl, Nelson N. H. Teng & Paul A. Wender. (2014) Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance. Molecular Pharmaceutics 11:8, pages 2553-2565.
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A. Hernández, N. Xamena, J. Surrallés, P. Galofré, A. Velázquez, A. Creus & R. Marcos. (2014) Role of GST and NAT2 polymorphisms in thyroid cancer. Journal of Endocrinological Investigation 31:11, pages 1025-1031.
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Nestor R. Rigual, Garth R. Anderson, Thom R. Loree, Sam Wiseman, Sadir Alrawi & Daniel L. Stoler. (2005) Molecular Prognosticators and Genomic Instability in Papillary Thyroid Cancer. The Laryngoscope 115:8, pages 1479-1485.
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Alba Hernández, Walkiria Céspedes, Noel Xamena, Jordi Surrallés, Amadeu Creus, Pere Galofré & Ricardo Marcos. (2003) Glutathione S-transferase polymorphisms in thyroid cancer patients. Cancer Letters 190:1, pages 37-44.
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Stanley Mukanganyama, Mikael Widersten, Yogeshkumar S. Naik, Bengt Mannervik & Julia A. Hasler. (2001) Inhibition of glutathione S‐transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance. International Journal of Cancer 97:5, pages 700-705.
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Alexander L Vahrmeijer, Rob W.M Hoetelmans, Gerard J Mulder, Jan Schutrups, Ronald L.P van Vlierberghe, Cornelis J.H van de Velde & Jan Hein van Dierendonck. (2000) Development of resistance to glutathione depletion-induced cell death in CC531 colon carcinoma cells: association with increased expression of Bcl-2. Biochemical Pharmacology 59:12, pages 1557-1562.
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Thomas Kunze & Stefan Heps. (2000) Phosphono analogs of glutathione: inhibition of glutathione transferases, metabolic stability, and uptake by cancer cells. Biochemical Pharmacology 59:8, pages 973-981.
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Fang-Yang Wu, Fuu-Jen Tsai, Hsien-Wen Kuo, Chang-Hai Tsai, Wu-Yui Wu, Ruey-Yun Wang & Jim-Shoung Lai. (2000) Cytogenetic study of workers exposed to chromium compounds. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 464:2, pages 289-296.
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Lesley I. McLellan & C.Roland Wolf. (1999) Glutathione and glutathione-dependent enzymes in cancer drug resistance. Drug Resistance Updates 2:3, pages 153-164.
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Sanjay K. Srivastava, Sharad S. Singhal, Xun Hu, Yogesh C. Awasthi, Piotr Zimniak & Shivendra V. Singh. (1999) Differential Catalytic Efficiency of Allelic Variants of Human GlutathioneS-Transferase Pi in Catalyzing the Glutathione Conjugation of Thiotepa. Archives of Biochemistry and Biophysics 366:1, pages 89-94.
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Maudy CMJ Stroombergen & Rosemary H Waring. (2016) Determination of glutathione S-transferase μ and τ polymorphisms in neurological disease. Human & Experimental Toxicology 18:3, pages 141-145.
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Hung-Yi Chiou, Yu-Mei Hsueh, Ling-Ling Hsieh, Ling-I Hsu, Yi-Hsiang Hsu, Fang-I Hsieh, Min-Li Wei, Hsiang-Chih Chen, Hui-Ting Yang, Lan-Chin Leu, Tzu-Hsien Chu, Chuan Chen-Wu, Mo-Hsiung Yang & Chien-Jen Chen. (1997) Arsenic methylation capacity, body retention, and null genotypes of glutathione S-transferase M1 and T1 among current arsenic-exposed residents in Taiwan. Mutation Research/Reviews in Mutation Research 386:3, pages 197-207.
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Thomas Kunze. (1997) Purification and Characterization of Class Alpha and Mu Glutathione S-Transferases From Porcine Liver. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 116:4, pages 397-406.
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Thomas Kunze. (2006) Phosphono Analogues of Glutathione as New Inhibitors of Glutathione S‐Transferases. Archiv der Pharmazie 329:11, pages 503-509.
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